Yazar "Ozbeyaz, Ceyhan" seçeneğine göre listele

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    Genetic diversity of two Holstein cattle herds in Turkey
    (INDIAN VETERINARY JOURNAL, 2006) Tozluca, Abdurrahman; Yildiz, Mehmet Ali; Ozbeyaz, Ceyhan
    The objectives of this study were to determine population structure and to assess the level of genetic differentiation between subpopulations of some Holstein breeds through the use of blood protein and enzyme polymorphism.
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    Genetic variability among native dog breeds in Turkey
    (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2013) Erdogan, Metin; Tepeli, Cafer; Brenig, Bertram; Akbulut, Mine Dosay; Uguz, Cevdet; Savolainen, Peter; Ozbeyaz, Ceyhan
    In this study, the genetic structures and relationships of native Turkish dog breeds were investigated using 20 polymorphic loci (17 microsatellites and 3 proteins). For this aim, a total of 141 blood samples were taken from Turkish shepherd dogs and Turkish Greyhounds located in several geographical regions of Turkey. Multilocus F-ST values indicated that around 1.92% of the total genetic variation could be explained by breed differences and the remaining 98.08% by differences among individuals. The gene flow between populations within each generation varied between 8.4 (Akbash-White Kars Shepherd dog pairs) and 62.3 (Black-Grey Kars Shepherd dog pairs). Four different groups appeared in the 3-dimensional factorial correspondence analysis, and among these, dogs from the Akbash, Kangal, Kars Shepherd, and Turkish Greyhound breeds grouped in clearly separated clusters in distant parts of the 3-dimensional graph. These results clearly show that Akbash and Kangal Shepherd dogs are different populations with different genetic structures. Therefore, the generalised grouping of Turkish shepherd dogs into a single breed called Anatolian or Turkish shepherd dogs is incorrect.
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    Identification of factor XI deficiency in Holstein cattle in Turkey
    (BIOMED CENTRAL LTD, 2009) Meydan, Hasan; Yildiz, Mehmet A.; Ozdil, Fulya; Gedik, Yasemin; Ozbeyaz, Ceyhan
    Background: Factor XI (FXI) is a plasma protein that participates in the formation of blood clots. Factor XI deficiency is autosomal recessive hereditary disorder that may be associated with excess bleeding in Holstein cattle. Methods: In this study, 225 Holstein cows reared in Turkey were screened in order to identify FXI genotypes. DNA extractions were obtained from the fresh blood of the cows. Amplicons of FXI exon 12 were obtained by Polymerase Chain Reaction (PCR), and analyzed by 2% agarose gel electrophoresis stained with ethidium bromide. Additionally, all cows were confirmed by DNA sequencing to determine whether or not there was a mutant allele. Results: Carriers of the FXI deficiency have two DNA fragments of 320 bp and 244 bp in size. The results of our study demonstrated that only four out of the 225 Holstein cows tested in Turkey carried the FXI deficiency. The frequency of the mutant FXI allele and the prevalence of heterozygous cows were found as 0.9% and 1.8%, respectively. Conclusion: The DNA-based test determines all genotypes, regardless of phenotype or FXI activity. The mutation responsible for the FXI deficiency had not been detected in Holstein cattle in Turkey before prior to this study. The frequency of the mutant FXI allele needs to be confirmed by carrying out further analyses on cattle in Turkey and the selection programs should be developed to eliminate this genetic disorder.