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    Assessing eco-toxicological effects of industrial 2,4-D acid iso-octylester herbicide on rat pancreas and liver
    (INFORMA HEALTHCARE, 2013) Kalipci, E.; Ozdemir, C.; Oztas, H.
    We studied the eco-toxic and carcinogenic effects of a commonly used 2,4-D acid iso-octylester herbicide on rat liver and pancreas. The rats in Group 1 were fed a standard feed and the rats in Group 2 were fed with standard feed to which was added 200 mg/kg/day 2,4-D acid iso-octylester for 16 weeks. Azaserine, 30 mg/kg/body weight, was injected into rats of Groups 3 and 4 to investigate the effects of 2,4-D acid iso-octylester on the development of neoplasms. After feeding the rats with neoplasms in Group 4 with food including 200 mg/kg/day 2,4-D acid iso-octylester for 16 weeks, an autopsy was carried out on all animals. We found that 2,4-D acid iso-octylester caused the formation of atypical cell foci (ACF) in the pancreata and livers of rats. ACF that were formed experimentally by exposure to azaserine had increased diameter, volume and number of atypical cell foci/mm 2 and mm 3 after exposure to 2,4-D acid iso-octylester. Our observations indicated that this herbicide potentially is a cancer initiator.
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    Clinical and genetic heterogeneity of hyper IgE syndrome in a Turkish cohort
    (WILEY-BLACKWELL PUBLISHING, INC, 2008) Keles, S.; Karakoc-Aydiner, E.; Ozdemir, C.; Reisli, I; Camcioglu, Y.; Somer, A.; Kutukculer, N.
    [Abstract not Available]
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    Removal of trichloroethylene (TCE) in up flow anaerobic sludge blanket reactors (UASB)
    (DIAGNOSIS PRESS LTD, 2007) Ozdemir, C.; Dursun, S.; Karatas, M.; Sen, N.; Sahinkaya, S.
    Low concentrations of chlorinated aliphatic compounds may be found in wastewater and contaminated soils from different industrial sources and in the air arising from these sources. Low levels of Volatile Organic Compounds (VOC) can be removed by adsorption, incineration and biofiltration methods. These methods have some disadvantages, such as low removal efficiency or high operation costs. Chlorine has been removed from the chlorinated aliphatic compounds by anaerobic conditions. The aim of this research was the investigation of biological treatment of VOC,v in high flow speed reactors. The resistance capacity of micro-organisms was investigated in an upflow anaerobic sludge blanket reactor (UASB) with automated control system, by feeding with co-substrate additions, by loading by different ratios of organic matter varying hydraulic retention time (HRT), maintaining stable concentrations of COD and Volatile Fatty Acids (VFA), pH,alkalinity, temperature (35 degrees C) etc. during the anaerobic treatment. Glucose, sodium sulphate, calcium chloride, ammonium bicarbonate, potassium phosphate and methanol were used as the co-substrates. In these studies the removal rates of TCE were opproximately 86.4-90. 0 %. The decomposition ratios were calculated for TCE as 0,231 mg g(-1)VSS d(-1). The highest methane ratio in the obtained biogas was 67.8 %,for TCE. Also, inhibition concentrations (IC) in 24 hours were determined as IC50,(.)31. 1 and IC25,(.) 9.9.