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Öğe Antiproliferative and apoptotic effects of noscapine on MCF-7 and MDA-MB-231 human breast cancer cell lines(WILEY-BLACKWELL, 2016) Kocak, F. E.; Kocak, C.; Ozturk, B.; Tekin, G.; Vatansev, H.[Abstract not Available]Öğe Bond strengths of two ceramic laminate systems to bleached enamel(MANEY PUBLISHING, 2011) Ozturk, A. Nilgun; Ozturk, B.; Malkoc, M. Arslan; Buyukozer, T.The aim of this study was to evaluate the microtensile bond strengths of ceramic laminate veneers bonded to bleached and non-bleached enamel. Ninety-six extracted maxillary central incisors were divided into two groups of 48 specimens each, bleached group and non-bleached group. After bleaching, teeth were prepared to accommodate veneers of equal thickness. Two ceramic systems, Cerec 3 and IPS Empress 2, were used for restoration. Each of the two ceramic groups was luted with Variolink 2 and RelyX veneer cement. Specimens were then subjected to tensile forces. The bond strength values were analysed with two-way analysis of variance and Tukey honestly significant difference tests. Microtensile bond strength significantly reduced after bleaching procedure (p < 0.05). Variolink 2 resin cement showed higher bonding strength than RelyX veneer cement (p < 0.05). The results of this in vitro study suggest that the bleaching procedure is an important factor on the bonding effectiveness of ceramic laminate veneers.Öğe Brefeldin A exerts differential effects on various phenotypes of breast cancer cell lines(WILEY-BLACKWELL, 2016) Tekin, G.; Ozturk, B.; Ozer, E. K.; Bariskaner, H.; Unlu, A.[Abstract not Available]Öğe Dipeptidyl peptidase-IV and Adenosine deaminase enzyme activity levels in Polycystic Ovary Syndrome(OXFORD UNIV PRESS, 2017) Gurbuz, A. S.; Ozturk, B.[Abstract not Available]Öğe Effect of a re-wetting agent on bond strength of an adhesive to primary and permanent teeth dentin after different etching techniques(MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2015) Yildiz, E.; Karaarslan, E. S.; Simsek, M.; Cebe, F.; Ozsevik, A. S.; Ozturk, B.Objective: This study investigated the effect of a re-wetting agent on the microtensile bond strengths (mTBS) of primary and permanent dentin after acid or laser etching. Materials and Methods: Twelve permanent and 12 primary molar teeth were ground to expose an occlusal dentin surface. Each group teeth were randomly divided into groups; I-II: 37% phosphoric acid etching with/without re-wetting agent, III-IV: Erbium: Yttrium aluminium garnet laser etching with/without re-wetting agent. An etch-and-rinse adhesive was used, and vertical sticks were obtained for the microtensile test. Results: mTBS of permanent teeth was higher than that of primary teeth (P < 0.05). Re-wetting agent groups were similar with control groups in both etching groups in the permanent teeth (P > 0.05). Re-wetting agent group was similar with the control group in acid etch group (P > 0.05) and lower than the control group in laser etch group in primary teeth (P < 0.05). Conclusion: Acid etching in permanent teeth; laser etching in primary teeth was found more successful. The use of re-wetting agent did not provide an advance on bond strength of the adhesive in both primary and permanent teeth after acid-etch or laser-etch.Öğe Effect of Erbium:yttrium aluminum garnet laser on bond strength of a total-etch adhesive system to caries-affected dentin on gingival wall(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2017) Cebe, F.; Bulbul, M.; Simsek, I.; Cebe, M. A.; Ozturk, B.Purpose: To assess the effect of the erbium:yttrium aluminum garnet (Er:YAG) laser on bond strength of a total-etch adhesive system to the caries-affected dentin on the gingival wall. Materials and Methods: Ten human molars with proximal carious lesions were randomly divided into two groups. In the first group, the carious dentin was removed with a bur, whereas in the second group it was removed with the Er:YAG laser. Carious lesions were excavated with one of these two techniques until laser fluorescence values decreased to 15 in the center of the lesions. The teeth were then restored with a total-etch adhesive system (Adper Single Bond 2) and composite resin (Filtek Z250). Five teeth from each group were sectioned to obtain 1 mm(2) stick-shaped microtensile specimens from each tooth. Twenty-five specimens were obtained for each group with using this technique. The data were analyzed in independent-samples t-test (a = 0.05). For each removal technique, one sample was analyzed using scanning electron microscopy. Results: No statistically significant differences were found between the bond strength of the Er:YAG laser and the bur-treated groups (P > 0.05). Conclusion: The Er:YAG laser treatment did not negatively affect the bonding performance of the total-etch adhesive system to caries-affected dentin on the gingival wall.Öğe Effect of static magnetic field with antiproliferative compounds on MDA MB-231 cell line(WILEY, 2017) Tekin, G.; Ozturk, B.[Abstract not Available]Öğe Effects of astragalus, lemon balm, clove, fenugreek and cinnamon on blood glucose level after oral glucose loading in rats(WILEY-BLACKWELL, 2013) Ozturk, B.; Ozturk, H. Serdar; Durak, I.[Abstract not Available]Öğe Evaluation of micro-tensile bond strength of caries-affected human dentine after three different caries removal techniques(ELSEVIER SCI LTD, 2012) Karaarslan, E. Sirin; Yildiz, E.; Cebe, M. A.; Yegin, Z.; Ozturk, B.Objective: This study evaluated the effect that different techniques for removing dental caries had on the strength of the microtensile bond to caries-affected human dentine created by three bonding agents. Materials and methods: Forty-five human molar teeth containing carious lesions were randomly divided into three groups according to the technique that would be used to remove the caries: a conventional bur, an Er:YAG laser or a chemo-mechanical Carisolv (R) gel (n = 15). Next, each of the three removal-technique groups was divided into three subgroups according to the bonding agents that would be used: Clearfil (R) SE Bond, G-Bond (R), or Adper (R) Single Bond 2 (n = 5). Three 1 mm(2) stick-shaped microtensile specimens from each tooth were prepared with a slow-speed diamond saw sectioning machine fitted with a diamond-rim blade (n = 15 specimens). For each removal technique one dentine sample was analysed using scanning electron microscopy. Results: There were statistically significant differences in the resulting tensile strength of the bond among the techniques used to remove the caries and there were also statistically significant differences in the strength of the bond among the adhesive systems used. The etch-and-rinse adhesive system was the most affected by the technique used to remove the caries; of the three techniques tested, the chemo-mechanical removal technique worked best with the two-step self etch adhesive system. Conclusion: The bond strength values of the etch-and-rinse adhesive system were affected by the caries removal techniques used in the present study. However, in the one- and two-step self etch adhesive systems, bond strength values were not affected by the caries removal techniques applied. While a chemo-mechanical caries removal technique, similar to Carisolv (R), may be suggested with self etch adhesive systems, in caries removal techniques with laser, etch-and-rinse systems might be preferred. Clinical significance: Caries removal methods may lead to differences in the characteristics of dentine surface. Dentine ultra structure generally affects the bonding of adhesive materials commonly used in restorative dentistry. Whereas etch-and-rinse system, like the ones used in the present study, are affected by these changes, the self etch systems are not affected. Hence, clinicians may opt for caries removal methods and systems appropriate for each patient and practice. (c) 2012 Elsevier Ltd. All rights reserved.Öğe High cholesterol diet leads to oxidant load and peroxidation in the rabbit kidney tissue(COMENIUS UNIV, 2016) Ozturk, B.; Ozer, O.; Durak, Z. E.; Billur, D.; Kizil, S.; Durak, I; Ozturk, H. S.OBJECTIVES: The aim of this study was to investigate possible effects of high cholesterol diet on oxidant/antioxidant status in rabbit kidney tissues. BACKGROUND:Although a number of experimental animal models have suggested that hyperlipidemia is associated with progressive kidney failure data remain sparse on the role of dietary cholesterol intake on kidney disease. METHODS: Twelve male New Zealand albino rabbits were randomly divided into two groups (control and cholesterol). Both groups were fed on a standard laboratory diet. Animals in the cholesterol group additionally received cholesterol (1 g/kg/day), orally. The study period was 12 weeks. Activities of catalase (CAT), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), nitric oxide synthase (NOS), xanthine oxidase (XO), paraoxonase (PON), adenosine deaminase (ADA) enzymes and levels of malondialdehyde (MDA) and nitric oxide (NO) were measured in kidney tissue samples. Histological examination of the kidney tissue samples was also done. RESULTS: SOD, GSH-Px and XO enzyme activities were found to be decreased and NOS and PON activities increased significantly in cholesterol group compared to controls. As an indication of oxidation, MDA levels were found to be increased in cholesterol group. Histological examination revealed some derangements in the kidney tissue. CONCLUSION: High cholesterol diet creates oxidant load and causes peroxidation, which in turn, leads derangements in the rabbit kidney tissue (Tab. 2, Fig. 2, Ref. 69). Text in PDF www.elis.sk.Öğe Serum oxidant and antioxidant status of patients with chronic tension type headache: possible effects of medical treatment(ELSEVIER SCIENCE BV, 2015) Cokal, B. Gokce; Aytac, B.; Durak, Z. E.; Gunes, H. N.; Ozturk, B.; Guler, S. Keskin; Durak, I.[Abstract not Available]
