Yazar "Sümer Ş." seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim Yok
    Öğe
    Anthrax in upper eyelid [Üst göz kapa?inda şarbon]
    (2013) Köktekir B.E.; Sümer Ş.; Gedik Ş.; Okudan S.
    Anthrax is an acute infection caused by Bacillus anthracis. Although it is a zoonotic disease that mainly affects herbivorous animals, it might also be contagious to humans by infected animals. The most common type is skin anthrax. When eyelid is involved; echymosis, bulla formation and necrosis can be observed. We report a 75 years old woman presenting with bilateral extensive lid echymosis and edema and diagnosed as anthrax. The clinical findings resolved with appropriate systemic and topical antibiotic treatment, and the lesions on the eyelid resulted with scatrizating ectropion. In failure of early diagnosis and treatment, there is a high risk of mortality and sequela with this particular disease which rarely involves eyelids.
  • Küçük Resim Yok
    Öğe
    Atypical HSV encephalitis with initial negative polymerase chain reaction for HSV DNA [Polii?meraz zii?ncii?r reaksii?yonu ii?le başlangiç HSV-DNA'si negatii?f olan atii?pii?k hsv ensefalii?tii?]
    (Nobelmedicus, 2014) Sümer Ş.; Ural O.
    HSV-DNA in cerebrospinal fluid by polymerase chain reaction is considered as the gold standard in the diagnosis of Herpes Simplex Virus (HSV) encephalitis. Sometimes the test may be negative in the initial stage of the disease. HSV-DNA quantitation by polymerase chain reaction should be repeated in 3-7 days if a patient is thought to have HSV encephalitis, as indicated by electroencephalography / magnetic resonance imaging of brain findings even though the initial HSV-DNA quantitation by polymerase chain reaction is negative. We presented two cases with a tentative diagnosis of HSV encephalitis with atypical course, whose polymerase chain reaction results were negative for HSV-DNA initially.
  • Küçük Resim Yok
    Öğe
    The importance of sonication in the diagnosis of prosthetic joint infections [Prostetik eklem enfeksiyonlarinin tanisinda sonikasyonun önemi]
    (Nobelmedicus, 2017) Sümer Ş.; Erkoçak Ö.F.; Arslan U.; Fındık D.; Dağı H.T.; Aydın B.K.; Demir N.A.
    Objective: The objective of this study is to investigate the efficacy of sonication method used to determine the cause in the diagnosis of prosthetic joint infections (PJI). Material and Method: This study included 30 patients who were operated due to prosthesis infection and as a control group 10 patients whose prostheses were removed due to mechanical reasons and who had no sign of infection. Cultures were prepared from these tissue samples through gram staining and conventional methods. The prostheses removed from the patients were put into the sonication device in sterile water with ringer lactate. After sonication, Gram staining, cultures and polymerase chain reaction (PCR) were made. Results: During the Gram staining done prior to the sonication, microorganisms were found in six patients (20%); after the sonication, microorganisms were seen in nine patients (30%), but this difference was not statistically significant (p>0.05). While agents were found in the cultures of 11 patients (36.7%) that were prepared using the conventional method, agents were found in 20 patients (66.7%) with the sonication method. The rate of detecting the agent in the culture prepared after sonication was statistical significantly higher than in the culture prepared with conventional methods (p=0.004). The sensitivity of PCR was found 63.3%. Conclusion: The sonication method of PJI is basically a procedure performed to increase the detectability of microorganisms. We found in the present study that the sonication method was obviously more precise than conventional methods in the microbiological diagnosis of PJI. © 2017, Nobelmedicus. All rights reserved.
  • Küçük Resim Yok
    Öğe
    Plasmodium falciparum and Salmonella Typhi co-infection:A case report [Plasmodium falciparum ye Salmonella Typhi Koenfeksiyonu: Bir Olgu Sunumu]
    (2014) Sümer Ş.; Ural G.; Ural O.
    Malaria and salmonella Infections are endemic especially in developing countries, however malaria and salmonella co-infection is a rare entity with high mortality. The basic mechanism in developing salmonella co-infection is the impaired mobilization of granulocytes through heme and heme oxygenase which are released from haemoglobin due to the breakdown of erythrocytes during malaria infection. Thus, a malaria infected person becomes more susceptible to develop infection with Salmonella spp. In this report a case with Plasmodium falciparum and Salmonella Typhi co-infection was presented. A 23-year-old male patient was admitted to hospital with the complaints of diarrhea, nausea, vomiting, abdominal pain, fatigue and fever. Laboratory findings yielded decreased number of platelets and increased ALT, AST and CRP levels. Since he had a history of working in Pakistan, malaria infection was considered in differential diagnosis, and the diagnosis was confirmed by the detection of P.falciparum trophozoites in the thick and thin blood smears. As he came from a region with chloroquine-resistant Plasmodium, quinine (3 x 650 mg) and doxycycline (2 x 100 mg/day) were started for the treatment. No erythrocytes, parasite eggs or fungal elements were seen at the stool microscopy of the patient who had diarrhoea during admission. No pathogenic microorganism growth was detected in his stool culture. The patient's blood cultures were also taken In febrile periods starting from the time of his hospitalization. A bacterial growth was observed in his blood cultures, and the isolate was identified as S. Typhi. Thus, the patient was diagnosed with P.falciparum and Salmonella Typhi coinfection. Ceftriaxone (1 x 2 g/day, 14 days) was added to the therapy according to the results of antibiotic susceptibility test. With the combined therapy (quinine, doxycycline, ceftriaxone) the fever was taken under control, his general condition improved and laboratory findings turned to normal values. However, on the fifth day of his anti-malaria therapy sudden bilateral hearing loss developed due to quinine use. Thus, the treatment was replaced with an artemisinin-based (arthemeter/lumefantrine) combination therapy. No adverse effects were detected due to artemisinin-based therapy, and the patient completely recovered. In conclusion, if a patient is diagnosed with malaria, he/she should be closely monitored in terms of having co-infections and appropriate diagnostic methods including blood cultures taken in febrile episodes should be performed.