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    Effects of fasting and preoperative feeding in children
    (W J G PRESS, 2009) Yurtcu, Muslim; Gunel, Engin; Sahin, Tahir Kemal; Sivrikaya, Abdullah
    AIM: To investigate whether children should undergo surgery without a long period of fasting after feeding. METHODS: Eighty children with inguinoscrotal disorders (aged 1-10 years) were studied prospectively. They were divided into eight groups that each contained 10 children who were fed normal liquid food (NLF) and a high-calorie diet (HCD) 2, 3, 4 and 5 h before surgery, in two doses at 6-h intervals. NLF was given to four groups and HCD to the other four. In all groups, glucose, prealbumin and cortisol levels in the blood were measured twice: just after oral feeding and just before the operation. After the establishment of adequate anesthesia, gastric residue liquid was measured with a syringe. RESULTS: Blood glucose levels in all patients fed NLF and HCD were high, except in patients in, the HCD-4 group. There was no significant difference in the blood prealbumin levels. There was a significant increase in the blood cortisol levels in the NLF-2 (14.4 +/- 5.7), HCD-2 (13.2 +/- 6.0), NLF-3 (10.9 +/- 6.4), and HCD-5 (6.8 +/- 5.7) groups (P < 0.05). CONCLUSION: The stress of surgery may be tolerated by children when they are fed up to 2 h before elective surgery. (C) 2009 The WJG Press and Baishideng. All rights reserved.
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    Left ventricular diastolic function evaluated with tissue Doppler imaging in children with familial Mediterranean fever
    (SPRINGER LONDON LTD, 2009) Baysal, Tamer; Peru, Harun; Oran, Bulent; Sahin, Tahir Kemal; Koksal, Yavuz; Karaaslan, Sevim
    The aim of this study was to assess the left ventricular diastolic function using conventional echocardiography and tissue Doppler imaging in children with familial Mediterranean fever. This study included 29 (13 males and 16 females) patients and 30 healthy subjects as controls. Body mass index was calculated and arterial blood pressure was monitored. After an overnight fast, venous blood samples were taken and serum amyloid A protein, C-reactive protein, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol levels were measured. A complete 2-dimensional, M-mode, pulse wave Doppler, and pulse wave tissue Doppler echocardiographic examination was performed. There were no significant differences between the groups regarding age, body mass index values, systolic and diastolic blood pressures, heart rates, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol. Serum levels of inflammatory markers were higher in patients' group (C-reactive protein and serum amyloid A protein levels were 10.84 mg/dl, 22.32 mg/l in patients' group, respectively, and 4.11 mg/dl, 3.65 mg/l, respectively, in the healthy controls.) Peak mitral A wave, E and A wave ratio differed significantly in both groups. There were statistically significant differences regarding parameters observed by tissue Doppler imaging such as E'm, A'm, E'm, and A'm ratio between patients' group and controls. Tissue Doppler imaging provided additional information on left ventricular diastolic function. While systolic functions were in normal range, some of the diastolic function parameters were impaired in patients with familial Mediterranean fever during childhood.
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    Serum and Cerebrospinal Fluid Magnesium Levels, Glasgow Coma Scores, and In-Hospital Mortality in Patients with Acute Stroke
    (HUMANA PRESS INC, 2009) Bayir, Ayseguel; Ak, Ahmet; Kara, Hasan; Sahin, Tahir Kemal
    The aim of this study was to determine the relationship between serum and cerebrospinal fluid (CSF) magnesium (Mg(+2)) levels, Glasgow Coma Scores (GCS), and 7-day mortality in acute stroke patients. Patients with acute ischemic or hemorrhagic stroke arriving within the first 3 h of symptoms were included in the study. The control group consisted of healthy volunteers. GCS was determined, and blood and CSF samples were taken in order to establish serum and CSF glucose, Mg(+2), sodium, potassium, calcium, and chlorine levels. Mortality was recorded at 7 days after admission. CSF Mg(+2) in the ischemic infarct group was significantly lower than in the control group (p = 0.006). CSF Mg(+2) in the ischemic infarct patients with a GCS a parts per thousand currency signaEuro parts per thousand 8 were significantly lower (p = 0.002) than controls and in ischemic infarct patients with a GCS a parts per thousand yen9. In the ischemic stroke patients, CSF Mg(+2) and GCS were significantly correlated (r = 55, p = 0.031). CSF Mg(+2) levels in ischemic stroke patients who died within 7 days were significantly lower than controls, ischemic stroke patients who survived, and hemorrhagic stroke patients who died (p = 0.002, p = 0.042, and p = 0.005, respectively). Low CSF Mg(+2) levels in patients with acute ischemic stoke at admission predicted a higher 1-week mortality.