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Öğe Add-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report(KURE ILETISIM GRUBU A S, 2009) Zeytinci, Esra; Uguz, Faruk; Sahingoz, Mine; Sari, Serap; Kayhan, FatihAdd-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report Despite a wide range of alternative antidepressant drugs, a considerable rate of patients with dysthymic disorder do not response to these treatments. Usually combined pharmacological drugs and augmentation therapies are used to manage this chronic psychiatric disorder. Pramipexole, a new dopamine agonist, is approved for Parkinson's disease and restless leg syndrome but accumulating evidence suggests the usage of the drug as an antidepressant. We present a young man with a history of dysthymic disorder for 15 years who improved after adding low dose pramipexole to the prior treatment.
