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    Anxiety and depression in medical students related to desire for and expectations from a medical career.
    (2010) Karaoglu N.; Seker M.
    In this article, we aimed to analyse the anxiety and depression levels of medical student's related to their desire for a career in medicine and expectations from that career. In a cross-sectional design, students from the first two years of medical school filled-out a questionnaire consisting of demographics, Hospital Anxiety and Depression Scales (HADS) and questions about their medical career decision. The mean anxiety score was 7.66 +/- 3.21 and the mean depression score was 5.77 +/- 3.45. According to cut-off levels, 20.3% of medical students had anxiety, 29.3% had depressive symptoms. Males and second year students had significantly high levels of depression (p < 0.05). Students who were pressured to become doctors and who expected to gain much money were both more anxious and more depressed (p < 0.05). External pressures, desire to become a medical doctor and expectations from a medical education have significant effects on anxiety and depression levels of medical students. Guidance for affected students is important and this is the responsibility of medical educators and faculties.
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    Developmental variations and clinical importance of the fetal thyroid gland: A morphometric study
    (2007) Cicekcibasi A.E.; Salbacak A.; Seker M.; Ziylan T.; Tuncer I.; Buyukmumcu M.
    Objetives: To investigate the morphologic structures and developmental anomalies of the thyroid gland in human fetuses. Methods: This study performed in the Department of Anatomy, Meram Faculty of Medicine between February and April in 2002. Fetuses were obtained from the Gynecology Department of the Meram Faculty of Medicine, Selçuk University, and Dr. Faruk Sukan Maternity Hospital (Konya, Turkey), Sixty spontaneously aborted fetuses (30 boys and 30 girls) between the ages of 13.5th and 32.5th weeks, which had no detectable anomalies, were evaluated. The gland was dissected under the microscope. The location of the gland was determined according to the tracheal ring levels and laryngeal cartilage levels. The length, width and thickness of both lobes and isthmus of the gland were measured and then, the developmental anomalies were noted. The obtained data were statistically analyzed by Least Squares in variant analysis. Results: Although there was no significant difference regarding to the gender for all parameters except in width of the right lobe (p<0.05), difference in the length and width of lobes and the length of isthmus between trimesters was significant (p<0.05). All measured parameters were increasing with advancing gestational age. The pyramidal lobe was observed in 18.3% of the cases. Conclusion: Normal dimensions and developmental anomalies of the fetal thyroid, which was shown in this study, may provide useful information for the prenatal diagnosis and in-utero treatment of thyroid dysfunctions.
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    Treatment modalities in primary gastric lymphoma: The effect of rituximab and surgical treatment. A study by the Anatolian Society of Medical Oncology
    (Termedia Publishing House Ltd., 2014) Mehmet K.; Sener C.; Uyeturk U.; Seker M.; Tastekin D.; Tonyali O.; Balakan O.
    Aim of the study: Gastrointestinal lymphoma is the most common type of extranodal lymphoma and commonly involved site is the stomach. We have compared the superiority between treatment modalities for primary gastric lymphoma and we want to investigate efficacy of rituximab in gastric lymphoma. Material and methods: Between April 2002 and December 2011, 146 patients with a histologically confirmed primary gastric lymphoma, initially diagnosed at eight different Cancer Centers within Turkey were evaluated retrospectively. According to the treatment modality, the patients were divided into chemotherapy (CT) alone, chemotherapy and radiotherapy (CRT), surgery and chemotherapy (SCT), surgery along with chemotherapy and radiotherapy (SCRT), and surgery (S) alone groups. Results: Median follow-up period was 25.5 months. The 5-year EFS (event free survival) and OS (overall survival) rates for the patients were 55% and 62.3% respectively. In Log rank analysis of OS and EFS, we have identified levels of albumin and hemoglobine, IPI score, stage at diagnosis as factors influencing survival. In multivariate analysis of OS and EFS, only albumin and stage at diagnosis were factors independently contributing to survival. There was no statistically significant difference in terms of survival between different treatment modalities (p = 0.707 in EFS and p = 0.124 in OS). In analysis of patients treated with chemotherapy alone, there was no a statistically significant difference in terms of EFS and OS between chemotherapy regimens with or without rituximab in localized and advanced stage groups (p = 0.264 and p = 0.639). There was no statistical difference in survival rate (EFS and OS) between surgical or non-surgical treatment modalities for localized/advanced stage gastric lymphoma groups (p = 0.519 / p = 0.165). Conclusions: There are several treatment options due to similar results in different treatment modalities. Also benefit of rituximab treatment in gastric lymphoma is still a controversial subject. Additional prospective trials are definitely required in order to clarify use of rituximab in treatment of extranodal gastric lymphoma.