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Öğe The effects of nitroglycerin in the zone of stasis in a rat burn model [Sıçanlarda deneysel yanık modelinde oluşan staz zonunda nitrogliserinin etkisi](Turkish Association of Trauma and Emergency Surgery, 2020) Gündüz M.; Sekmenli T.; Uğurluoğlu C.; Çiftçi İ.BACKGROUND: Studies evaluating the recovery of the zone of stasis is an important issue in burn research. In this study, we aimed to evaluate and compare the efficiency of an anti-ischemic and vasodilatory agent, a topical agent containing 2% nitroglycerin with 1% silver sulfadiazine, and bacitracin-neomycin sulfate in the zone of stasis histomorphologically and immunohistochemically. METHODS: We conducted an experimental study using 30 Wistar-Albino rats, each weighing 250–300 grams. The rats were divided randomly into five groups (six rats in each group). In this study, the “comb model,” which was deemed to be the most appropriate experimental model to produce an injury with predictable zones and was first described by Regas and Erhlich, was used. The following were applied to the zone of stasis after creating a burn model in 0, 24, and 48 hours: topical 2% nitroglycerin, 1% silver sulfadiazine, bacitracin-neomycin sulfate, and Vaseline-lanolin (sham). After 72 hours, biopsies were performed from the zone of stasis and evaluated by histomorphological and immunohistochemical CD 34 (expressed in human endothelial and hematopoietic cells) and D 2–40 (expressed in the endothelium of lymphatic capillaries) methods. The results were evaluated using the chi-square test. RESULTS: Compared with the other groups, a statistically significant difference was found in edema, inflammation, and vascular proliferation in the nitroglycerin group. Significantly more intense staining for CD 34 was found in the nitroglycerin group compared with the other groups. Immunohistochemical staining for D 2-40 was also found statistically significant in the nitroglycerin group (p<0.05). CONCLUSION: A topical containing 2% nitroglycerin increases vascular proliferation in the zone of stasis affects the recovery and may be used as a new agent in burn injury treatment. © 2020 Turkish Association of Trauma and Emergency Surgery.Öğe How safe is anastomosis near the ileocecal valve in distal ileal pathologies? [Distal ileum patolojilerinde ileoçekal valve yakın anastomoz ne kadar güvenli?](Logos Medical Publishing, 2016) Sekmenli T.; Gündüz M.; Çiftci I.Aim: We aimed to evaluate the operative findings, and follow-up of a patient who had partial ileal necrosis due to brid ileus,who had ileo-ileal anastamoses 5 cm proximal to ceacum. Case report: A 1.5 year old boy was admitted to the pediatric emergency department of our hospital with abdominal pain and vomiting. The image of flat soft tissue mass at abdominal midline on standing direct radiograms was observed. During the abdominal examination, a palpable painful mass sense was present. In exploration, an adhesion band involving approximately 60 cm of the terminal ileum and squeezing the mesentery vessels was seen, and excised. As the lukewarm water compress for 5-10 minutes did not reverse the ischemia, we decided to resect, and remove gangrenous ileal segments. Considering the current toxic condition, a temporary double-barrel ileostomy was made using the distal loop at a 5 cm proximal to terminal ileum and proximal viable ileal segment. The preoperative body weight of the case decreased for 14 kg due to the intensive loss of fluid from the stoma, despite medical support from the pediatric gastroenterology department, after 14 days to 11.5 kg. Then closure of the stoma was decided on the 16th postoperative day In order to preserve ileocecal valve end- to-end anastomosis was performed, 5 cm proximal to terminal ileum. Stool frequency decreased, and its content became denser, and at the 12th postoperative day patient was discharged without any problems. During the control visit in the 1st month following hospital discharge the clinical findings of the case were normal and the patient weighed 14.5 kg. Conclusions: In cases well prepared before the operation and intervened with the most appropriate surgical technique and appropriate surgical materials, we consider that anastomosis close to the terminal ileum will not lead to any problems clinically. We believe that anastomosis preserving ileocecal valve will increase the quality of life especially in children with longer life expectancy. However larger series are necessary to verify the findings of the present study. © Cocuk Cerrahisi Dergisi. All rights reserved.Öğe Letters to the editor [Cartas al editor](Sociedad Argentina de Pediatria, 2018) Sekmenli T.; Gündüz M.; Ciftci I.; Emirolu H.H.; Koplay M.[Abstract not Available]Öğe Our results lymphadenopathy biopsy in children: A review of the literature [Çocuklarda Lenfadenopati Biyopsi Sonuçlarimiz: Literatürün Gözden Geçirilmesi](OrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2016) Sekmenli T.; Çiftci I.; Köksal Y.Objective: Lymphadenopathy, is one of the most common presenting complaints in pediatricians routine. Parental concerns about the removal of the malignancy is a challenge for physicians. In our clinic, we aimed to evaluate retrospectively cases due to biopsy lymphadenopathy. Material and Methods: The medical records of the patients diagnosed with lymphadenopathy and underwent a biopsy between January 2011 and January 2014 in our clinic were examined retrospectively. The files of these patients were studied for the variables of age, gender, location, histopathology results, and symptoms. Results: 23 patients, 16 male and 7 female, had been conducted a diagnostic biopsy due to lymphadenopathy. The average age of the patients was 8.8 (1-17). Out of these 23 biopsies conducted, the histopathological findings in 10 patients suggested lymphadenitis, in 9 benignant lesions, and in 4 malignant lesions. Out of the 10 patients, diagnosed with lymphadenitis, 3 had chronic granulomatous lymphadenitis. Conclusion: Diagnosis can be sufficient most cases to be in detailed history and physical examination. Etiology in most cases is limited and a role in infections and benign structures such as nonspecific reactive hyperplasia. In order to clarify the etiology and and discard malignity in lymphadenopathies, a biopsy made according to the indication clears the path of the clinician. Copyright © 2016 by Tür ki ye Kli nik le ri.Öğe Short-gap Isolated Esophageal Atresia Causing Stridor Due to Compression of the Trachea(2015) Sekmenli T.; Ciftci İ.; Sivri M.; Koplay M.Isolated esophageal atresias are reported always to be associated with long gap in the literature. In this manuscript, we aimed to discuss the imaging and surgical treatment methods of an isolated esophageal atresia case with 'short gap' who had stridor due to compression of the trachea by dilated upper esophageal pouch and had not identified previously in the literature.Öğe Surgical therapy for pilonidal sinus in adolescents: A retrospective study(Medical Association of Zenica-Doboj Canton, 2015) Sekmenli T.; Ciftci I.Aim To investigate optimal surgical management of pilonidal sinus (PS) in pre-adolescent and adolescent periods in which it is less common. Methods A retrospective study based on 25 adolescent patients with PS disease that were treated at the Department of Pediatric Surgery, Selcuk University, Konya, Turkey, between 2010 and 2013 was conducted. Results Among 25 patients with PS disease 17 (68%) were males and eight (32%) females, with a mean age of 16.08 ± 1.2 years. According to the body mass index (BMI), 17 (68%) of the cases were in the normal range, 4 four (16%) of each were overweight, and obese, respectively. Twenty cases (80%) were managed with total excision and primary closure, while five (20%) cases underwent Limberg flap repair. Four patients were managed with the Limberg procedure due to very large sinuses, while a single patient underwent the procedure due to a recurrence following primary repair. Conclusion Factors that predispose patients to developing PS include an above average BMI, significant body hair, and prolonged time in a seated position. Elevated BMI as a risk factor for PS is a growing concern given the rise in obesity. Although there are various treatment modalities, total excision and primary closure has demonstrated successful outcomes. © 2015 Medical Association of Zenica-Doboj Canton. All rights reserved.Öğe Unusual complication of bladder catheterization in child: catheterization of ureter(2015) Sekmenli T.; Ciftci I.Bladder probing is an invasive procedure that is often used by paediatric and other surgeons. We present a case who was ureter catheterized accidentally while placing a probe into the right ureter in an 18 months old female. If different catheter localization is determined during the examination, the process must be terminated immediately and the relevant specialist should be informed right away.
