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Öğe Brain damage after radiotherapy and treatment [Radyoterapi sonrasi beyin hasari ve tedavi yaklaşimlari](2006) Genç M.; Ergun U.; Selek U.Radiation-induced norotoxicity is a rare but serious complication. Although primary target cells are endothelial and glial cells, radiation-induced norotoxicity is thought to result from complex dynamic interactions between parenchymal and vascular cells within the central nervous system. Despite advances in imaging techniques, diagnosis of radiation necrosis remains as a challenge and definite diagnosis requires histopathological examination. Some cases show improvement after surgical resection. Corticosteroids are used both in prophylaxis and treatment. Currently, there are studies going on investigating the effects of many agents including growth factors and stem cells on prophylaxis and treatment of radiation-induced norotoxicity.
