Yazar "Sert, Ibrahim Unal" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Fuzzy expert system design for operating room air-condition control systems
    (PERGAMON-ELSEVIER SCIENCE LTD, 2009) Etik, Nazmi; Allahverdi, Novruz; Sert, Ibrahim Unal; Saritas, Ismail
    In this study, a controlled fuzzy expert system (FES) was designed to provide the conditions necessary for operating rooms. For this purpose, existing operating rooms have been Studied to see if there are more useful, reliable and comfortable ones. How an operating room can be controlled with FES and its advantages and disadvantages have also been researched. For a theoretically visible FES to show system's advantage a prototype operating room was built and a suitable configuration was designed. In this system, heat, humidity, oxygen and particles were used as input parameters, and a fresh air entrance and fail circulation were chosen as output parameters. With the help of all expert, appropriate linguistic expressions and the membership function of these expressions were defined. The sensors were classified and sensor information was transferred to computer by means of an interface designed. In order to transfer the data to the system simultaneously, an interface was written in C#. Whether it provides the most suitable control for the system prototype was determined by simulating the operation with varying numbers of patients and operation personnel. In these trials, input, output and other necessary parameters were collected in the computer. In the study, we obtained excellent results in prototype operating room control with FES. The analyses of the results carried out indicated that the controls performed with FES provide more economical, comfortable, reliable and consistent controls and that they are feasible in a real operating room. (C) 2009 Elsevier Ltd. All rights reserved.
  • Küçük Resim Yok
    Öğe
    Preliminary feasibility study of a new method of hypothermia in an experimental canine model
    (AVES, 2017) Sert, Ibrahim Unal; Akand, Murat; Kilic, Ozcan; Yavru, Nuri; Bulut, Ersan
    Objective: To build up a new microcontroller thermoelectric system to achieve renal hypothermia. Material and methods: Renal hypothermia system was tested under in vivo conditions in the kidneys of ten Mongrel dogs. Ambient temperature was evaluated using two different microcontrollers. In order to ensure hypothermia in the renal parenchyma, selection can be made among 4 modules and sensors which detect the temperature of the area. The temperature range of the system was adjusted between -50 degrees C and + 50 degrees C. Results: When single and double poles of the kidney were cooled, initial mean intraperitoneal temperature values were found 37.7 degrees C for rectum and 36.5 degrees C for renal cortex and medulla. After the temperature of the cooling module was set to 12 degrees C, the module was placed on the poles of the kidney. After fifteen minutes, temperature was 15.4 degrees C in the lower pole of the kidney, 28.1 degrees C in the cortex of the other side and 29.2 degrees C in the intramedullary region. The temperature was found to be 15 degrees C in the vicinity and 26.1 degrees C in the cortex across the module. After the system was stabilized, a very slight change was observed in the temperature. Conclusion: Hypothermia system developed ensured desired cooling of the targeted part of the kidney; however, it did not cause a change in the temperature of other parts of the kidney or general body temperature. Thus, it was possible to create a long-term study area for renal parenchymal surgery.
  • Küçük Resim Yok
    Öğe
    The role of vitamin E in the prevention of zoledronic acid-induced nephrotoxicity in rats: a light and electron microscopy study
    (TERMEDIA PUBLISHING HOUSE LTD, 2018) Sert, Ibrahim Unal; Kilic, Ozcan; Akand, Murat; Saglik, Lutfi; Avunduk, Mustafa Cihat; Erdemli, Esra
    Introduction: Bisphosphonates are widely used in metastatic cancer such as prostate and breast cancer, and their nephrotoxic effects have been established previously. In this study we aimed to evaluate both the nephrotoxic effects of zoledronic acid (ZA) and the protective effects of vitamin E (Vit-E) on this process under light and electron microscopy. Material and methods: A total of 30 male Sprague-Dawley rats were divided into 3 groups. The first group constituted the control group. The second group was given i.v. ZA of 3 mg/kg once every 3 weeks for 12 weeks from the tail vein. The third group received the same dosage of ZA with an additional i.m. injection of 15 mg Vit-E every week for 12 weeks. Tissues were taken 4 days after the last dose of ZA for histopathological and ultrastructural evaluation. Paller score, tubular epithelial thickness and basal membrane thickness were calculated for each group. Results: For group 2, the p-values are all < 0.001 for Paller score, epitelial thickness, and basal membrane thickness. For group 3 (ZA + Vit. E), the p-values are < 0.001 for Paller score, 0.996 for epitelial thickness, and < 0.001 basal membrane thickness. Significant differences were also observed in ultrastructural changes for group 2. However, adding Vit-E to ZA administration reversed all the histopathological changes to some degree, with statistical significance. Conclusions: Administration of ZA had nephrotoxic effects on rat kidney observed under both light and electron microscopy. Concomitant administration of Vit-E significantly reduces toxic histopathological effects of ZA.