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Öğe The association between coronary artery disease and nonalcoholic fatty liver disease and noninvasive imaging methods(MODESTUM LTD, 2019) Koplay, Mustafa; Gok, Mustafa; Sivri, MesutCoronary artery disease (CAD) is the number one cause of death globally and imaging plays a pivotal role in the diagnosis and management of CAD. With the improvements in technology, noninvasive imaging methods become more widely used in the management of CAD. Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome which affects a substantial proportion of general population and is a component of the metabolic syndrome (MetS). Histopathologic analysis is the reference standard to detect and quantify fat in the liver, but results are vulnerable to sampling error. Imaging can be repeated regularly and allows assessment of the entire liver, thus avoiding sampling error so imaging is in key role in the management of NAFLD as in CAD. As NAFLD is a component of MetS, it is associated with increased risk for CAD. Recent studies suggest a more complex picture of the interrelation between NAFLD, MetS and CAD, and raised the possibility that NAFLD might not only be a marker but also an early mediator for CAD. So early detection of NAFLD and its management with noninvasive imaging methods can be very crucial in the control of CAD which is the number one cause of death globally.Öğe An atypical isolated CNS blast crisis in chronic myeloid leukaemia(MA HEALTHCARE LTD, 2018) Sivri, Mesut; Paksoy, Yahya; Dagli, Mehmet; Kelesoglu, Kazim Serhan; Koplay, Mustafa[Abstract not Available]Öğe Bilgisayarlı tomografi eşliğinde transtorasik akciğer biyopsisi yapılan hastaların sonuçlarının değerlendirilmesi ve komplikasyonlara eşlik eden risk faktörlerinin belirlenmesi(Selçuk Üniversitesi Tıp Fakültesi, 2016) Sivri, Mesut; Nayman, AlaaddinBu retrospektif çalışmadaki amacımız kliniğimizde BT eşliğinde yapılan transtorasik biyopsilerin tanıdaki doğruluk oranlarını, güvenilirliğini, komplikasyon oranlarını değerlendirmek ve komplikasyonların gelişimine etki eden faktörleri saptamaktır. GEREÇ YÖNTEM: 191 hastanın 194 BT görüntüsü incelenmiştir. Yatış pozisyonu, lezyon yerleşimi, boyutu ve özellikleri, komplikasyon gelişip gelişmediği, komplikasyon tipi, deri/plevra ve plevra/lezyon mesafesi, füssürün geçilip geçilmediği, amfizem varlığı, iğnenin plevraya giriş açısı, ko-aksiyel kullanılıp kullanılmadığı değerlendirilmiştir. Hastaların demografik bilgileri, kullanılan iğne türü ve boyutu, patoloji sonuçları ve takipleri Hastane Bilgi Yönetim Sisteminden (HBYS) bakılmıştır. BULGULAR: İİAB'nin tanısal doğruluk oranı benign lezyonlarda %81, malign lezyonlarda %91 ve tüm lezyonlar açısından bakıldığında %84 bulunmuştur. Tru-cut biyopsi ile benign lezyonlarda tanısal doğruluk oranı %84, malign leyonlarda %95 ve tüm lezyonlarda %91 bulunmuştur. Hemoraji en sık görülen komplikasyon olup 31oranında görülmüştür. İkinci sıklıkla %29 ile pnomotoraks mevcuttur. Lezyon çapı, yerleşimi, plevra/lezyon mesafesi ile hemoraji arasında istatiksel olarak anlamlı fark bulunmuştur. Deri/plevra mesafesi ve hemoraji ile arasındaki ilişkiye bakıldığında Deri/plevra mesafesi ile tip 1 hemoraji gelişimi açısından anlamlı fark bulunmuştur. Deri/plevra mesafesi azaldıkça tip 1 hemorajinin daha az olduğu görülmüştür. Pnomotoraks ile olan ilişkiye bakıldığında amfizem, lezyon boyutu, fissürün geçilmesi, plevra/lezyon mesafesi istatiksel olarak anlamlı fark bulunan parametrelerdir. SONUÇ: BT eşliğinde yapılan perkutan biyopsi işlemleri uygulanabilirliği kolay, düşük maliyetli, tanısal doğruluk oranları yüksek, ciddi komplikasyon oranları düşük güvenilir bir yöntemdir. Tanısı konulmamış akciğer lezyonlarının tanısında öncelikle tercih edilmesi gerekmektedir.Öğe Cervical giant pseudomeningocele presented with neck pain: conventional MRI and MR myelography findings(ELSEVIER SCIENCE INC, 2016) Cebeci, Hakan; Koplay, Mustafa; Sivri, Mesut; Paksoy, Yahya[Abstract not Available]Öğe Comparison Between Prospectively Electrocardiogram-Gated High-Pitch Mode and Retrospectively Electrocardiogram- Gated Mode for Dual-Source CT Coronary Angiography(INT SCIENTIFIC INFORMATION INC, 2015) Koplay, Mustafa; Celik, Mahmut; Avci, Ahmet; Erdogana, Hasan; Demir, Kenan; Sivri, Mesut; Nayman, AlaaddinBackground: We aimed to report the image quality, relationship between heart rate and image quality, amount of contrast agent given to the patients and radiation doses in coronary CT angiography (CTA) obtained by using high-pitch prospectively ECG-gated "Flash Spiral" technique (method A) or retrospectively ECG-gated technique (method B) using 128x2-slice dual-source CT. Material/Methods: A total of 110 patients who were evaluated with method A and method B technique with a 128x2-detector dual-source CT device were included in the study. Patients were divided into three groups based on their heart rates during the procedure, and a relationship between heart rate and image quality were evaluated. The relationship between heart rate, gender and radiation dose received by the patients was compared. Results: A total of 1760 segments were evaluated in terms of image quality. Comparison of the relationship between heart rate and image quality revealed a significant difference between heart rate <60 beats/min group and >75 beats/min group whereas <60 beats/min and 60-75 beats/min groups did not differ significantly. The average effective dose for coronary CTA was calculated as 1.11 mSv (0.47-2.01 mSv) for method A and 8.22 mSv (2.19-12.88 mSv) for method B. Conclusions: Method A provided high quality images with doses as low as <1 mSv in selected patients who have low heart rates with a high negative predictive value to rule out coronary artery disease. Although method B increases the amount of effective dose, it provides high diagnostic quality images for patients who have a high heart rate and arrhythmia which makes it is difficult to obtain images.Öğe Diagnostic accuracy and effective radiation dose of high pitch dual source multidetector computed tomography in evaluation of coronary artery bypass graft patency(SPRINGER WIEN, 2016) Koplay, Mustafa; Guneyli, Serkan; Akbayrak, Hakan; Demir, Kenan; Sivri, Mesut; Avci, Ahmet; Erdogan, HasanThe aim of the study was to evaluate the diagnostic accuracy and effective radiation dose (ERD) of high pitch dual source multidetector computed tomography (MDCT) for coronary artery bypass graft (CABG) patency. Fourty-five patients who underwent 128 x 2aEuroslice MDCT angiography with a prospective electrocardiogram-triggering, low-dose, high pitch, dual source, flash spiral acquisition mode after CABG surgery were included in the study. The interobserver agreement of the image quality was evaluated with Cohen kappa value. The image quality was compared to the heart rates (HRs) using Mann-Whitney U test and to the graft segments using chi(2) test. The findings for the CABG patency on MDCT were compared to those determined on catheter coronary angiography. Dose-length product (DLP) and ERD were compared to the gender, HRs, and body mass index (BMI) of the patients using Kruskall Wallis and Mann-Whitney U tests. A total of 110 grafts and 330 vessel segments were evaluated with a good interobserver agreement (kappa = 0.80). The image quality was better in proximal and middle graft segments (p < 0.05), as well as in the patients with low HRs (p < 0.05). High pitch MDCT had the following sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy for evaluation of graft patency: 92.8, 99.3, 92.8, 99.3 and 98.8 %, respectively. ERD was correlated to the HRs and BMI. High pitch 128 x 2aEuroslice dual source CT angiography is a noninvasive imaging modality, and it can be safely and effectively used in evaluation of CABG patency with lower radiation dose.Öğe Diagnostic efficacy of diffusion-weighted MRI for pre-operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma(WILEY-BLACKWELL, 2014) Koplay, Mustafa; Dogan, Nasuh Utku; Erdogan, Hasan; Sivri, Mesut; Erol, Cengiz; Nayman, Alaaddin; Karabagli, PinarIntroduction: To determine the diagnostic accuracy of diffusion-weighted magnetic resonance imaging (DW-MRI) for the pre-operative assessment of patients with endometrial carcinoma and to assess myometrial and cervical invasion as well as pelvic lymph node metastasis. Methods: Fifty-eight women who underwent surgery for histopathologically confirmed endometrial carcinoma were included in the current study. Prior to surgery, patients were evaluated using pelvic DW-MRI and gadolinium-enhanced T1-weighted imaging (Gd-T1WI). Gd-T1WI was evaluated together with T2-weighted images. DW-MR images were obtained in the axial plane using echo-planar spin-echo pulse sequences with different b factors. Endometrial carcinomas were observed as areas of increased intensity on DW-MRI images, and their intensity was compared with the surrounding hypo-intense myometrium. Pre-operative DW-MRI and Gd-T1WI results were compared with post-operative histopathological findings that served as reference standards. Results: The sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and diagnostic accuracy of DW-MRI for differentiation between superficial myometrial invasion and deep myometrial invasion were 85%, 89%, 81%, 92% and 88%, respectively. The sensitivity, specificity and diagnostic accuracy rates were 82%, 91% and 89.6% for cervical invasion and 100%, 96% and 96.5% for pelvic lymph node metastasis, respectively. The sensitivity, specificity, PPV and NPV, and diagnostic accuracy of Gd-T1WI for differentiation between superficial myometrial invasion and deep myometrial invasion were 85%, 81.5%, 71%, 91% and 83%, respectively. The sensitivity, specificity and diagnostic accuracy were 73%, 89% and 86% for cervical invasion, respectively. Conclusions: These findings suggest that DW-MRI may be a good diagnostic tool with high sensitivity and specificity for assessing myometrial invasion and detecting tumour extension. We suggest that DW-MRI should be considered as a routine part of the pre-operative pelvic MRI in all patients with endometrial carcinoma.Öğe Ectopic Pregnancy in a Cesarean Section Scar: Successful Management Using Vacuum Aspiration under Laparoscopic Supervision-Mini Review of Current Literature(HINDAWI LTD, 2016) Koplay, Mustafa; Dogan, Nasuh Utku; Sivri, Mesut; Erdogan, Hasan; Dogan, Selen; Celik, CetinA cesarean scar ectopic pregnancy (CSEP) is a fairly uncommon presentation wherein the conceptus is implanted deep in the myometrium and at the exact scar site of the previous cesarean section. There are various CSEP management options that range from medical treatment to surgical interventions such as dilatation and curettage, laparoscopic excision, resection by laparotomy, or, sometimes, a combination of these modalities. Establishing a diagnosis of CSEP can be challenging. Given the relatively rare incidence of CSEP, its management is controversial and current standards of therapy have been derived from data obtained from a limited number of patients. Herein, we present transvaginal ultrasonography (TVUS) imaging findings and management strategies used in a case of CSEP along with the short review of current literature.Öğe Gallbladder paraganglioma: computed tomography and magnetic resonance imaging findings(2014) Koplay, Mustafa; Sivri, Mesut; Alptekin, Hüsnü; Erdoğan, Hasan; Nayman, AlaaddinParagangliomas are benign tumors that can be association with sympathetic and parasympathetic nerves. More rarely, they can be located in the gallbladder. In this paper, we describe the appearance of an unusual case of paraganglioma in the gallbladder.Öğe Holospinal epidural abscess in a child patient: magnetic resonance imaging findings(ELSEVIER SCIENCE INC, 2015) Koplay, Mustafa; Sivri, Mesut; Emiroglu, Melike Keser; Guler, Ibrahim; Karabagli, Hakan; Paksoy, Yahya[Abstract not Available]Öğe Importance of imaging and recent developments in diagnosis of nonalcoholic fatty liver disease(BAISHIDENG PUBLISHING GROUP INC, 2015) Koplay, Mustafa; Sivri, Mesut; Erdogan, Hasan; Nayman, AlaaddinNonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease and is a major public health problem worldwide. It is a spectrum that includes simple steatosis, nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis. Recently, NAFLD prevalence in children and adolescents has increased too. The increasing prevalence has resulted in NASH-related chronic liver disease. Therefore, early diagnosis and treatment is quite important. Although liver biopsy is still the gold standard for diagnosis and staging of NAFLD, particularly for the diagnosis of NASH, imaging methods such as ultrasonography, computed tomography, magnetic resonance imaging with chemical shift imaging and especially magnetic resonance spectroscopy and elastography have been increasingly approved as noninvasive alternative methods. The aim of this review is to analyze the diagnostic accuracy and limitations of the imaging methods and recent developments in the diagnosis of NAFLD.Öğe Interesting X-ray and computed tomography images of a cervical trauma patient(TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2016) Kalkan, Havva; Emlik, Ganime Dilek; Sivri, MesutPatients admitted to emergency departments with loss of consciousness following trauma often have cervical vertebrae fractures and spinal cord injuries with a ratio of 5-10%. Computed tomography (CT) and radiography are important for diagnosis. The aim of this study was to describe the interesting CT and radiography findings of a patient who had C3-4 dislocation anddistraction that was called shearing injury. C3 and C4 were seperated, but there was no fracture or major vascular injuries. Images were interesting. NEXUS and Canadian Rules were also referred to for clinical evaluation. Imaging modalities, espacially reformatted CT images, make it easier to diagnose where and what the problem is.Öğe Intradural extramedullary spinal hydatid cyst causing bone destruction(ELSEVIER SCIENCE INC, 2015) Koplay, Mustafa; Sivri, Mesut; Erdogan, Hasan; Nayman, Alaaddin[Abstract not Available]Öğe İntrakranial lipomlar: Yerleşim yerleri ile birlikte bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulguları(2015) Keleşoğlu, Kazım Serhan; Sivri, Mesut; Erdoğan, Hasan; Koplay, Mustafa; Güneyli, SerkanAmaç: Bu çalışmanın amacı, nadir doğumsal malformasyonlardan olan intrakranial lipomların bilgisayarlı tomografi (BT) ve manyetik rezonans görüntüleme (MRG) bulgularını incelemek, klinik bulgularını ve birliktelik gösterdikleri malformasyonları tespit etmek ve lezyon yerleri ile hem semptomlar hem de kalfikasyon varlığı arasındaki ilişkiyi tespit etmektir. Gereç ve yöntem: Mart 2010-Mart 2015 tarihleri arasında tanı alan intrakranial lipoma sahip 57 hastanın (22 erkek ve 35 kadın, ortalama yaş 50, 2-89 arası yaş) BT ve MRG bulgularını geriye dönük değerlendirdik. 25 hastanın BT, 32 hastanın MRG incelemesi mevcuttu. Lezyonların BT dansiteleri ölçüldü, görüntüleme bulguları, lezyon hacimleri, semptomlar ve birliktelik gösterdikleri lezyonlar tespit edildi. Lezyon yerleri ile hem semptomlar hem de kalsifikasyon varlığı arasındaki ilişki kikare testi kullanılarak araştırıldı. Bulgular: Lezyonların yerleşim yerleri şu şekilde izlendi; interhemisferik fissür (n22), sol kuadrigeminal sistern (n10), korpus kallozum (n10), interserebellar fissür (n4), sağ kuadrigeminal sistern (n3), interpedinküler sistern (n3), silvian fissür (n2), koroid pleksus (n2), sol akustik kanal (n1). Ortalama lipom hacmi 43,047 mm3 idi. En sık semptom 9 hastada görülen baş ağrısı idi. Lezyon yerleri, ne semptomlar (p0,394) ile ne de kalsifikasyon varlığı (p0,552) ile anlamlı ilişki göstermedi. Sonuç: BT ve MRG tipik özellikleriyle intrakranial lipomlara tanı koyabilmektedir ve de bu lezyonların birliktelik gösterdikleri diğer malformasyonları da ortaya koyabilmektedir. BT ve MRG özelliklerinin bilinmesi ayırıcı tanıyı kolaylaştırmaktadır.Öğe Öğe Maksiller fibröz displazinin egzofitik varyantı; Fibröz displazi protuberans(2014) Erdoğan, Hasan; Paksoy, Yahya; Sivri, Mesut; Erol, Cengiz; Uysal, Emine; Koplay, MustafaFibröz displazi, normal kemik dokunun yerini fibröz doku içeren mineralize bir dokunun aldığı, gelişimsel, neoplastik olmayan bir kemik hastalığıdır. Direkt radyografi, bilgisayarlı tomografi ve manyetik rezonans görüntüleme, fibröz displazi tanısında kullanılan radyolojik görüntüleme yöntemleridir. Bu yazıda maksiller fibröz displazinin oldukça nadir görülen egzofitik varyantının klinik özel- likleri, radyolojik görüntüleme bulguları ve ayırıcı tanısı sunulmuşturÖğe Measuring the Effect of Filters on Segmentation of Developmental Dysplasia of the Hip(KOWSAR PUBL, 2016) Kocer, Hasan Erdinc; Cevik, Kerim Kursat; Sivri, Mesut; Koplay, MustafaBackground: Developmental dysplasia of the hip(DDH) can be detected with ultrasonography (USG) images. However, the accuracy of this method is dependent on the skill of the radiologist. Radiologists measure the hip joint angles without computer-based diagnostic systems. This causes mistakes in the diagnosis of DDH. Objectives: In this study, we aimed to automate segmentation of DDH ultrasound images in order to make it convenient for radiologic diagnosis by this recommended system. Materials and Methods: This experiment consisted of several steps, in which pure DDH and various noise-added images were formed. Then, seven different filters (mean, median, Gaussian, Wiener, Perona and Malik, Lee, and Frost) were applied to the images, and the output images were evaluated. The study initially evaluated the filter implementations on the pure DDH images. Then, three different noise functions, speckle, salt and pepper, and Gaussian, were applied to the images and the noisy images were filtered. In the last part, the peak signal to noise ratio (PSNR) and mean square error (MSE) values of the filtered images were evaluated. PSNR and MSE distortion measurements were applied to determine the image qualities of the original image and the output image. As a result, the differences in the results of different noise removal filters were observed. Results: The best results of PSNR values obtained in filtering were: Wiener (43.49), Perona and Malik (27.68), median (40.60) and Lee (35.35) for the noise functions of raw images, Gaussian noise added, salt and pepper noise added and speckle noise added images, respectively. After the segmentation process, it was seen that applying filtering to DDH USG images had low influence. We correctly segmented the ilium zone with the active contour model. Conclusion: Various filters are needed to improve the image quality. In this study, seven different filters were implemented and investigated on both noisy and noise-free images.Öğe Meckel Gruber syndrome: A case report with review of literature(MODESTUM LTD, 2017) Uygun, Saime Sundus; Sivri, Mesut; Topsakal, Ahmet; Dikener, Ahmet Hakan; Soylu, Hanifi; Annagur, AliMeckel-Gruber syndrome, which is firstly described by Friedrich Meckel and Georg B. Gruber, is an autosomal recessive disorder that is characterized triad of occipital encephalocele, bilateral renal dysplasia and polydactyly. Because of the genetic heterogeneity, multiple organs can be affected. The worldwide incidence varies from 1 in 13,250 to 1 in 140,000 live births. We have reported a male baby born at 37-week gestation, who has occipital encephalocele, polydactyly and cystic dysplasia of both kidneys. As a result of these clinical findings, Meckel-Gruber Syndrome is suspected for his baby. This study is presented to draw attention to the Meckel Gruber Syndrome which has high risk of recurrence and early diagnosis by ultrasonographic screening can be confident.Öğe Microcystic meningioma: difficulties in diagnosis and magnetic resonance imaging findings(SPRINGER HEIDELBERG, 2017) Danisman, Mehmet Cagri; Kelesoglu, Kazim Serhan; Sivri, Mesut; Koplay, Mustafa; Paksoy, Yahya[Abstract not Available]Öğe Miyozitis ossifikans: Radyolojik görüntüleme bulguları(2013) Erdoğan, Hasan; Koplay, Mustafa; Sivri, MesutMiyozitis ossifikans (MO), yumuşak dokuda sıklıkla travmaya sekonder olarak oluşan ve ossifikasyon ile giden bir hastalıktır. Klinik ve histolojik olarak malign yumuşak doku tümörleri ile karışabilir. Direkt radyografi, ultrasonografi, bilgisayarlı tomografi ve manye- tik rezonans görüntüleme MO tanısında kullanılan radyolojik görüntüleme yöntemleridir. Bu çalışmada iki olguda MO'ın radyolojik görüntüleme bulgularını sunmayı amaçladık