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Öğe Acute myocardial infarction provoked by smoking and xylometazoline use in a patient with normal coronary arteries [Koroner arterleri normal olan bir hastada sigara ve ksilometazolin kullaniminin tetikledi?i akut miyokard infarktüsü](2006) Kayrak M.; Ülgen M.S.; Koç F.; Soylu A.Coronary vasospasm is a cause of acute coronary syndrome. Many factors, in particular smoking may induce vasospasm. Xylometazoline is a commonly used sympathomimetic to provide decongestive action with topical effect. A 50-year-old male patient was admitted with typical angina pectoris that developed after heavy smoking. Coronary angiography showed normal coronary anatomy. One month later, he presented with myocardial infarction of ST elevation following high dose of xylometazoline application. There was no other cause to provoke coronary vasospasm. This case underlines the need for a thorough investigation into drug use in young and relatively low-risk patients presenting with chest pain.Öğe Antidiabetic treatment in diabetic patients with coronary artery disease(2007) Soylu A.; Ülgen M.S.; Düzenli M.A.The prevalence of diabetes mellitus (DM) that is about 150 million today is estimated to exceed 300 million by the year 2025 (1). When considered that about half of the patients remain undiagnosed, it can be seen how serious the dimensions of the disease are (2). In the patients with DM more than 90% of whom are consisted by non-insulin dependent diabetes mellitus (NIDDM, Type 2 DM), the disease is a significant risk factor for the development of coronary artery disease (CAD) responsible for 75% of all deaths (3,4). In this group of the patients who generally require antidiabetic treatment inevitably, it is highly important to decide on an appropriate treatment due to the various cardiovascular (CV) effects of the anti-diabetics medications and drugs. In order to help establish this decision, in this review it was tried to investigate antidiabetic drugs after a general approach to CAD pathophysology in diabetic patients, especially in terms of their cardiovascular effects.Öğe Giant left ventricular pseudoaneurysm detected three years after myocardial infarction(2006) Soylu A.; Gök H.; Narin C.; Kayrak M.A 70-year-old male patient presented with symptoms of heart failure three years after having myocardial infarction. Transthoracic echocardiography revealed severely compromised left ventricular systolic function (ejection fraction 20%) and a large left ventricular pseudoaneurysm. The diagnosis was confirmed by computed tomography. The size of the pseudoaneurysm sac was 11 x9 cm. At surgery, the pseudoaneurysmal sac was resected and a defect of 3.5x4 cm was detected in the anterolateral wall of the left ventricle. The defect was repaired by the remodeling ventriculoplasty method of Dor. The patient whose general condition improved through intensive medical treatment was discharged with medications for heart failure and coronary artery disease on the 15th postoperative day.Öğe A lethal but treatable complication: Free wall rupture after acute myocardial infarction(2006) Ülgen M.S.; Öztürk Ö.; Kayrak M.; Soylu A.; Düzenli M.A.; Koç F.A 43-year-old male patient was admitted to coronary intensive care unit with the diagnosis of acute inferolateral myocardial infarction and with a picture of cardiogenic shock. In physical examination, systolic blood pressure was 50 mmHg and diastolic blood pressure could not be taken. The patient was diagnosed with cardiogenic shock and was started on saline, dopamine and dobutamine infusion. His blood pressure did not increase although the dosage of positive inotropic agents was increased. A cardiac tamponade revealed with urgent echocardiographic evaluation and pericardiocentesis was carried out. Blood pressure returned to normal range within hours after pericardiosentesis. Echocardiographic examination performed on the second day of AMI on the asymptomatic patient revealed thrombosed myocardial rupture. The patient was referred to emergency surgery with the diagnosis of three-vessel disease and myocardial rupture according to urgent angiography. In the operation, the ruptured region in the ventricle free wall was primarily repaired. By-pass surgery was performed with saphenous vein graft to the LAD and CV-OM1 coronary arteries.Öğe The oxidative stability of flavoured virgin olive oil: the effect of the water activity of rosemary(Springer Verlag, 2018) Kasimoglu Z.; Tontul I.; Soylu A.; Gulen K.; Topuz A.Flavoured olive oil gained has importance in terms of its sensorial properties and oxidative stability in recent years. However, the water activity level of the flavouring agent can be important for oxidative stability. Therefore, the aim of this study was to determine the effect of the water activity of rosemary, which was used as a flavouring agent, on the oxidative stability of olive oil. For this purpose, rosemary samples were adjusted to different levels of water activity (0.17, 0.24 and 0.44) and used for the aromatization of virgin olive oils. At the end of the aromatization, the olive oil samples were exposed to an accelerated oxidation test at 60 °C for 28 days. The peroxide, p-anisidine, TOTOX (total oxidation index), free fatty acid, chlorophyll, carotenoid and specific extinction values of the samples were determined. According to the results, the oxidation of olive oils is limited by decreased water activity values in the rosemary samples. Moreover, unflavoured oils were identified as being more sensitive to oxidation when compared to flavoured oils. Additionally, storage time had important effect on all of the analysed parameters. The present research showed that the water activity of rosemary, when used as condiment, affected the oxidative stability and carotenoid content of virgin olive oil. Using rosemary with a low water activity value to flavour olive oil was more effective in terms of oxidative stability. These findings implied that the oxidation of flavoured olive oil could be decreased by decreasing the water content of the condiment used. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.Öğe Removal of fractured balloon catheter using another balloon inflation in coronary artery: Case report(2006) Soylu A.; Ozdemir K.; Duzenli M.A.In this report, a novel management to the problem of a fractured balloon catheter which is a very rarely seen complication and has not yet been reported in the nature as in our case during percutaneous transluminal coronary interventions is presented. We inserted a second balloon catheter to the space between the previous fractured balloon and the wall of right coronary artery, and then by inflating the second balloon catheter at low pressure, the guide-wire of fractured balloon catheter and the second sound balloon catheter gently and cautiously removed together into the guiding catheter. Subsequently, the whole system was taken out of the body without complication. © 2006 Elsevier Ireland Ltd. All rights reserved.
