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Öğe The effects of preoperative chemotherapy and beta glucan on bronchial anastomosis in rabbits: a preliminary study(BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2015) Altuntaş, Bayram; Ceran, Sami; Sunam, Güven; Gültekin, Mustafa; Esen, HasanBackground: This study aims to investigate the effects of an immunostimulant, beta glucan, on the bronchial anastomosis in rabbits that received chemotherapy in preoperative period. Methods: Forty-five New Zealand male rabbits were used in this study. The rabbits were divided into three groups as group 1 (control), group 2 (chemotherapy), and group 3 (chemotherapy + beta glucan) with 15 rabbits in each group. The left main bronchus was incised completely and then end-to-end anastomosis was performed in all groups. Cisplatin was administered on the preoperative first day and etoposide was administered on the preoperative first, second, and third days in group 2. In group 3, in addition to the same chemotherapy protocol, 10 mg/kg/day beta glucan was administered via enteral route starting from seven days before operation until one day before sacrifications. The rabbits were sacrificed at postoperative third, fifth, and seventh days by groups of five. The bronchial anastomosis lines were removed and tissue sections were stained with hematoxylin and eosin. Results: In pathological analysis, while there were statistically significant differences between group 1 and group 2 and between group 2 and group 3, there was no difference between group 1 and group 3 in terms of bronchial healing. Conclusion: The use of beta glucan during chemotherapy treatment may improve bronchial healing at postoperative period.Öğe Pulmonary Artery Agenesis and Lung Hypoplasia(2009) Sunam, Güven; Ceran, SamiUnilateral pulmonary artery agenesis with lung hypoplasia is very rare and only a few cases have been reported in the literature. Some patients with hypoplasia may suffer from recurrent hemoptysis dyspnea, and lung infections. Other patients are asymptomatic. Chest X-Ray reveal a reduction in the volume of hemithorax, an elevation in the diaphragm, reduced intercostals spaces and mediastinal shift in the affected side. We present a 15 year old male patient who complained of shortness of breath and chest pain.Öğe Spontan Pnömotorakslı Olguların Değerlendirilmesi(2007) Gök, Mehmet; Ceran, Sami; Sunam, Güven; Uzun, KürşatAmaç: Spontan pnomotoraks iatrojenik ve travmatik pnomotoraks dışında herhangi bir presipite edici faktör olmaksızın kendiliğinden oluşan pnomotoraks türüdür. Gereç ve Yöntem: Bu çalışmada son 10 yıl içinde yatarak tedavi gören 164 spontan pnömotorakslı hastadan 20 pnömotorakslı kadın hasta retrospektif olarak değerlendirildi. Bulgular: Yatarak tedavi edilen olguların 6'sı primer spontan pnomotoraks iken, 14'ü sekonder spontan pnomotoraks idi. Bu olguların yaş aralığı 16-76 arasında değişiyor idi. Her iki grupta yaş dağılımı karşılaştırıldığında primer grupta yaş ortalaması 28 iken sekonder grupta 44.4 idi. Olgularımızın yapılan radyolojik incelemeleri sonucunda pnömotoraksın daha çok sağ (n:13, %65 ) tarafta ve total (n:ll, %55) olduğu gözlendi. Sonuç: Sonuç olarak kadınlarda sekonder spontan pnömotoraksın daha sık görüldüğü sebeplerinin çeşitli olduğu ve katamenial pnomotoraks ile karşılaşamadığı veya görülmediği söylenebilir.