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Effect of sildenafil (Viagra®) on penile erection and semen volume and characteristics in kangal dogs
(2009) Çoyan K.; Ataman M.B.; Özalp B.; Tepeli T. C.
In this study, the effects of sildenafil administration on penile erection and semen volume and characteristics in Kangal dogs were studied. A total of 5 Kangal dogs, aging 3-6 years, and with a known fertility were used. In each application, sildenafil was administered orally at a dosage of 50 mg, 60 minutes prior to semen collection. Semen was collected 12 times at 3-day intervals by digital manipulation. After collected, semen was examined for volume (first, second, and third fractions), ejaculation time, and spermatological characteristics. Dogs were rested for 3 weeks after the last semen collection. Following the rest period, semen collection was experienced 12 times at 3-day intervals by digital manipulation without sildenafil application. Sildenafil administration enhanced the volume of the second and third fractions, compared to the non-sildenafil group (1.1 ml versus 0.7 ml and 11 ml versus 6 ml, respectively, P<0.05), and increased the total ejaculation time (11.8 minutes versus 7 minutes, P<0.05). On the other hand, there were no significant differences between the sildenafil and non-sildenafil groups for spermatological characteristics (P>0.05). As a conclusion, sildenafil could be used in dogs, having problems in response to digital manipulation, for penile erection and successful semen collection.