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    Acute Renal Failure Secondary to Malignant Hypertension Induced Thrombotic Microangiopathy
    (Saudi Med J, 2010) Türkmen, Kültigin; Solak, Yalçın; Esen, Hasan; Tonbul, Halil Z.
    The thrombotic microangiopathy (TMA) represents a discreet group of disorders with common pathological features including fibrinoid necrosis, endothelial cell injury, and obstruction of vessels.1 The clinical presentation ofTMA includes microangiopathic hemolytic anemia, thrombocytopenia, and functional impairment of various organ systems. Hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are among the common causes of TMA. Patients with malignant hypertension are prone to TMA.
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    A Hepatitis C-Positive Patient with New Onset of Nephrotic Syndrome and Systemic Amyloidosis Secondary to Common Variable Immunodeficiency
    (K Faisal Spec Hosp Res Centre, 2010) Türkmen, Kültigin; Anıl, Melih; Solak, Yalçın; Atalay, Hüseyin; Esen, Hasan; Tonbul, Halil Z.
    Common variable immunodeficiency (CVID) is a heterogenous group of predominantly antibody deficiency disorders that make up the greatest proportion of patients with symptomatic primary hypogam maglobulinemia The rare coincidence of amyloidosis and hypogamma globulinemia has been reported previously Contrary to the usual insidious slowly progressive disease following hepatitis C infection a rapidly progressive cirrhotic form can develop in hypogammaglobulinemic patients We report a HCV positive patient with a new onset of nephrotic syndrome and systemic amyloidosis secondary to CVID Blood analyses showed serum creatininne of 1 8 mg/dL and serum albumin of 3 1 gm/dL 24 h urinary protein was 11 800 mg/day Serum immunoglobulin levels were IgG 340 mg/dL IgM 18 mg/dL IgA 11 mg/dL Duodenal biopsy revealed AA type amvloidosis with potassium permanganite and Congo red staining After a month of antiprotemuric therapy the proteinurin was reduced to 3350 mg/day
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    A rare human infection of Raoultella ornithinolytica in a diabetic foot lesion
    (K FAISAL SPEC HOSP RES CENTRE, 2011) Solak, Yalcin; Gul, Enes Elvin; Atalay, Huseyin; Genc, Nejdet; Tonbul, Halil Z.
    [Abstract not Available]