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Öğe Early and late urological complications corrected surgically following renal transplantation(WILEY, 2007) Dinckan, Ayhan; Tekin, Ahmet; Turkyilmaz, Serdar; Kocak, Huseyin; Gurkan, Alihan; Erdogan, Okan; Tuncer, MuratThe purpose of this study was to assess outcomes of urological complications after kidney transplantation operation. Nine-hundred and sixty-five patients received a kidney transplant between 2000 and 2006. In total, 58 (6.01%) developed urological complications, including urinary leakage (n = 15, 1.55%), stenosis (n = 29, 3%), vesicoureteral reflux (VUR) (n = 12, 1.2%), calculi (n = 1, 0.1%) and parenchymal fistulae (n = 1, 0.1%). Urinary leakage cases were treated by ureteroneocystostomy (UNS) via a double-J stent and stenosis cases by UNS. Fenestration was performed in patients developing lymphoceles and unresponsive to percutaneous drainage. VUR treatment was performed by ureteroneocystostomy revision or UNS. Stent usage during ureteric reimplantation was observed to reduce urinary leakage. Surgical complication rates in renal transplantation recipients according to donor type (living versus cadaveric) and the status of stent use (with stent versus without stent) were 5.53% vs. 7.27% (P = 0.064) and 5.24% vs. 20% (P < 0.01) respectively. No recurrence, graft loss or death was seen after these interventions. Comparison of recipients with and without urological complication showed that there was no difference between groups (P > 0.05) with respect to last creatinine level. No graft or patient loss was associated with urological complications. Urological complications that can be surgically corrected should be aggressively treated by experienced surgeons and graft loss avoided.Öğe Effects of Caffeic Acid Phenethyl Ester (CAPE) on Hepatopulmonary Syndrome(SPRINGER/PLENUM PUBLISHERS, 2011) Tekin, Ahmet; Turkyilmaz, Serdar; Kucukkartallar, Tevfik; Cakir, Murat; Yilmaz, Huseyin; Esen, Hasan; Ates, BurhanThe aim of this study was to investigate the effects of caffeic acid phenethyl ester (CAPE) on inflammatory and related histopathological changes in the lung and liver in experimental hepatopulmonary syndrome (HPS) model. Forty Sprague Dawley rats were used in this study. The animals were divided into four groups of ten rats each. Group 1 and 2 was subjected the common bile duct (CBD) but not ligated, Group 3; (cirrhosis + saline): the CBD was ligated and was given intraperitoneal saline infusion treatment during 5 weeks. Group 4; (cirrhosis + CAPE): the CBD was ligated and was given intraperitoneal CAPE infusion treatment during 5 weeks. A 5-week waiting period was observed for the development of cirrhosis and the rats' lungs and liver were taken for histopathological examination. The induction of HPS resulted in a significant increase in serum bilurubin, AST, ALT, and NO levels, and decrease PO2 and O-2 saturation. The use of CAPE significant decrease these parameters. Histopathological examination revealed less congestion, portal inflammation, and nodular formations of the liver, and less congestion, emphysematous and inflammatory changes and smallest perialviolar vascular diameters, in the lung in the cirrhosis + CAPE groups than in the other groups. CAPE treatment may be a potential approach for the treatment of hepatopulmonary syndrome in the future.Öğe Shoe kidney for transplant: Report of 3 cases(BASKENT UNIV, 2007) Diuckan, Ayhau; Tekin, Ahmet; Turkyilmaz, Serdar; Kocak, Huseyin; Gurkan, Alihan; Erdogan, Okan; Tuncer, MuratOwing to the limited donor pool at transplant centers, grafts may be taken from marginal donors with congenital abnormalities, one of the most common of which is a fusion abnormality. Horseshoe kidneys may be transplanted to a single recipient en bloc or to 2 recipients after division. In our clinic, 3 grafts (1 obtained from a living donor and 2 from a deceased donor) were successfully transplanted to 3 patients. In select patients, horseshoe kidneys may be used for transplant.Öğe Simultaneous augmentation ileo-cystoplasty in renal transplantation(ELSEVIER SCIENCE INC, 2007) Dinckan, Ayhan; Turkyilmaz, Serdar; Tekin, Ahmet; Erdogru, Tibet; Kocak, Huseyin; Mesci, Ayhan; Gurkan, AlihanINTRODUCTION Renal transplantation is not contraindicated in end-stage renal disease developing as a result of complication of overactive bladder with uninhibited detrusor contractions. As an amendatory Surgical approach, augmentation ileo-cystoplasty is the preferred option to achieve a low intravesical storage pressure. However, the timing of the augmentation ileo-cystoplasty in combination with renal transplantation is still controversial. TECHNICAL CONSIDERATIONS We analyzed data from 3 of the 1100 renal transplantation patients treated at the Akdeniz University Transplantation Center in whom concomitant augmentation ileo-cystoplasty and renal transplantation were performed owing to hypocompliant bladder. CONCLUSIONS The operation times were 360, 270, and 240 minutes. No perioperative major complication or rejection was detected. Bladder augmentation using ileum patch can be concomitantly performed with renal transplantation safety, and this approach avoids the requirement for a second operation in another session.
