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Öğe The Effects of Fibromyalgia Syndrome on Female Sexuality: A Controlled Study(ELSEVIER SCI LTD, 2012) Yilmaz, Halim; Yilmaz, Sema Dereli; Polat, Halime Almula Demir; Salli, Ali; Erkin, Gulten; Ugurlu, HaticeIntroduction. Fibromyalgia may have negative effects on sexual function in women. Aims. To evaluate the sexuality of women with fibromyalgia and healthy control subjects, and to investigate the relation between sexuality and clinical parameters of fibromyalgia. Main Outcome Measures. Female Sexual Function Index (FSFI), Tender Points Count (TPC), Beck Depression Inventory (BDI), Fibromyalgia Impact Questionnaire (FIQ), and Visual Analog Scale (VAS). Methods. Clinical evaluation and surveys were done with 126 women with fibromyalgia and 132 healthy women. Results. Patients with fibromyalgia had higher BDI scores and lower frequency of sexual intercourse than control subjects. The mean FSFI scores (total and all domains) were significantly lower in patients with fibromyalgia than control subjects. Mean FSFI scores (total and most domains) were significantly lower in patients with fibromyalgia who had BDI score >= 17 than those who had BDI score < 17. In women with fibromyalgia, a significant negative correlation was noted between total FSFI score, and both FIQ and BDI scores. Conclusions. Fibromyalgia has negative effects on female sexual function that are aggravated by depression. Yilmaz H, Yilmaz SD, Polat HAD, Salli A, Erkin G, and Ugurlu H. The effects of fibromyalgia syndrome on female sexuality: a controlled study. J Sex Med 2012; 9: 779-785.Öğe Efficacy of therapeutic ultrasound in the treatment of spasticity: A randomized controlled study(IOS PRESS, 2011) Sahin, Nilay; Ugurlu, Hatice; Karahan, Ali YavuzThe purpose of this study was to investigate the effect of ultrasound (US) on the spasticity occurring in the ankle plantar flexor muscles after a cerebrovascular event. According to the modified Ashworth scale (MAS), the hemiplegic patients with stage 2-3 spasticity on the ankle plantar flexor muscles were enrolled in the study and divided into two groups. Passive stretching exercise was applied to both groups. Additionally, 10-minute US was applied to one of the groups, using the mode of continuous wave of 1.5w/cm(2) to the calf muscles before stretching. In order to monitor the efficacy of the treatment in the patients, MAS, Hmax/Mmax ratio, the ankle range of motion (ROM), Functional Independence Measure and Brunnstrom Motor Recovery Stage were evaluated. While a significant recovery was monitored in the MAS and ankle ROM measurements after treatment in both groups, no change was obtained in the other parameters. No significant difference was detected in any of the measurements between the groups. In this study, US treatment applied in combination with the ankle plantar flexor muscles passive stretching exercise was determined to have no effect on the stretching treatment in minimizing the spasticity.Öğe Evaluation of knee proprioception and effects of proprioception exercise in patients with benign joint hypermobility syndrome(SPRINGER HEIDELBERG, 2008) Sahin, Nilay; Baskent, Akin; Cakmak, Aysegul; Salli, Ali; Ugurlu, Hatice; Berker, EnderThe first aim is to show if there is a disorder in proprioception in cases with benign joint hypermobility syndrome (BJHS) when compared to healthy subjects. The second aim is to evaluate the effect of proprioception exercise in BJHS cases. To evaluate the proprioceptive sensibility of the knee joint with 40 BJHS and 30 healthy subjects enrolled in the study. Then, cases with BJHS were randomized into two groups; proprioceptive exercises were applied to 15 patients for 8 weeks in clinic and 25 patients were taken as controls. Outcome measures included proprioceptive sensation, AIMS2 and VAS. Proprioception is significantly impaired in cases with BJHS. In BJHS group, significant decreases in VAS levels were detected in cases who did exercise compared with cases who did not, and statistically significant improvements were detected in occupational activity. For this reason proprioception exercises cause decrease in pain and improvement of functional status in BJHS group.Öğe Evaluation of Sexual Dysfunction in Women with Rheumatoid Arthritis: A Controlled Study(ELSEVIER SCI LTD, 2012) Yilmaz, Halim; Polat, Halime Almula Demir; Yilmaz, Sema Dereli; Erkin, Gulten; Kucuksen, Sami; Salli, Ali; Ugurlu, HaticeObjective. To evaluate sexual function in women with rheumatoid arthritis (RA) and compare them with healthy controls. Materials and Methods. Ninety-five patients with RA and 108 healthy controls were included in the study. Depression levels and sexual functions of all participants were evaluated by the Beck Depression Inventory (BDI) and Index of Female Sexual Function (IFSF), respectively. Morning stiffness in women with RA, pain (Visual Analog ScaleVAS), disability rate (Health Assessment QuestionnaireHAQ), and disease activity score (DAS-28) were defined. Results. Total IFSF and mean of IFSF subgroup scores and significance of sexual life score were lower in patients with RA than controls, whereas mean BDI score was higher. The mean of the total IFSF scores was significantly lower in patients with RA with BDI =17 than that of patients with BDI <17. The mean of the total IFSF score decreased as disease severity increased. There was a strong negative correlation between total IFSF and DAS-28 scores, a moderate negative correlation between total IFSF score and HAQ, BDI, VAS score, age, and morning stiffness, and weak negative correlation between total IFSF and body mass index. Conclusion. RA is observed to have negative effects on sexual functions of women. Presence of depressive symptoms with RA and increased disease severity increase the degree of sexual dysfunction. Women patients with RA should also be asked about their sexual lives while being evaluated. Yilmaz H, Polat HAD, Yilmaz SD, Erkin G, Kucuksen S, Salli A, and Ugurlu H. Evaluation of sexual dysfunction in women with rheumatoid arthritis: A controlled study. J Sex Med **;**:****.Öğe Isokinetic evaluation of knee extensor/flexor muscle strength in patients with hypermobility syndrome(SPRINGER, 2008) Sahin, Nilay; Baskent, Akin; Ugurlu, Hatice; Berker, EnderBenign joint hypermobility syndrome (BJHS) is a syndrome with musculoskeletal pain originating from the increased laxity of the joints and the ligaments. The study was to compare the isokinetic strength of knee extensor/flexor muscles of BJHS patients with healthy controls. Forty patients diagnosed as having BJHS with Brighton criteria and 45 years of age, height and weight-matched healthy controls were recruited for the study. Isokinetic testing was performed with isokinetic dynamometry of Biodex System 3Pro and measurements were recorded at knee extension/flexion pattern concentrically at 60, 180, and 240/s angular velocities. The study group was also evaluated for functional impairment and pain by HAQ and VAS respectively. Knee extensor muscle strength was significantly lower in the patient group compared with the controls. It was hypothesized that the muscle weakness in the study group was related to lengthening of the quadriceps muscle and pain-related inactivity as well as joint instability and proprioception defect.Öğe A Placebo-Controlled, Multicenter, Randomized, Double-Blind, Flexible-Dose, Two-Way Crossover Study to Evaluate the Efficacy and Safety of Sildenafil in Men With Traumatic Spinal Cord Injury and Erectile Dysfunction(TAYLOR & FRANCIS LTD, 2008) Ergin, Sureyya; Gunduz, Berrin; Ugurlu, Hatice; Sivrioglu, Koncuy; Oncel, Sema; Gok, Haydar; Erhan, BelginBackground/Objective: To show the efficacy, safety, and tolerability of sildenafil in men with erectile dysfunction (ED) associated with complete or incomplete spinal cord injury (SCI) and to assess its effects on quality of life (QoL) using the Life-Satisfaction Check List. Methods: This was a placebo-controlled, multicenter, randomized, double-blind, flexible-dose, 2-way crossover study with a 2-week washout period between each phase. Patients with ED attributable to SCI (Sexual Health Inventory-Male score <= 21) received 50 to 100 mg sildenafil (n = 24) or placebo (n = 26). Results: Compared with placebo, sildenafil produced higher levels of successful sexual stimulation, intercourse success, satisfaction with sexual life and sexual relationship, erectile function, overall sexual satisfaction, and an improved Erectile Dysfunction Inventory of Treatment Satisfaction score, with no clinically relevant effects on vital signs. Sildenafil seemed more effective in patients with incomplete SCI than in those with complete SCI, producing significant improvements, compared with placebo, in a number of measures only in patients with incomplete SCI. All patients who expressed a preference selected sildenafil over placebo, although the drug had no effect on patient QoL. Sildenafil was well tolerated, with a profile comparable to that of placebo. Conclusions: Compared with placebo, treatment with oral sildenafil safely and effectively improved erectile function in patients with ED attributable to SCI, especially in those with incomplete injury, and was the agent of choice in those who expressed a preference.Öğe Reactive arthritis following tetanus vaccination: a case report(SPRINGER, 2009) Sahin, Nilay; Salli, Ali; Enginar, Ayse Unal; Ugurlu, HaticeWe report a case of reactive arthritis following tetanus vaccination. A healthy 55-year-old woman presented with pain and acute swelling of the right knee two days after receiving a tetanus vaccination. Erythrocyte sedimentation rate and C-reactive protein were elevated. Rheumatoid factor and human leukocyte antigen B-27 were negative. Her arthritis improved with the administration of nonsteroidal anti-inflammatory drugs. One week later the knee swelling and pain had settled. Reactive arthritis may occur after tetanus vaccination.Öğe Relationship between handgrip strength and isokinetic shoulder abduction-adduction muscle strength in primer fibromyalgia(TURKISH LEAGUE AGAINST RHEUMATISM-T L A R, 2008) Salli, Ali; Yilmaz, Halim; Kocabas, Hilal; Ugurlu, HaticeObjective: To compare grip strength and isokinetic shoulder abduction-adduction maximal muscle strength and to assess the correlation between hand grip strength (HGS) and shoulder strength in primer fibromyalgia patients with healthy controls. Patients and Methods: One hundred patient and 50 healthy women were included in this study. The patient's complaint duration and number of tender points were recorded. The visual analog scale was used for the assessment of pain. Beck depression scale and Fibromyalgia Impact Questionnaire (FIQ) were calculated. Handgrip strength was measured using a handgrip dynamometer and the highest value of sequential 3 measurements was recorded. Isokinetic shoulder abduction-adduction maximal muscle strength was measured at 60 and 180 degrees/sec. All patients' dominant side was assessed. The strength was calculated as the mean of five consantric isokinetic repetations. Results: There was no statistical difference between patients and the control group in age and body mass index (BMI). The mean HGS was 0,41 +/- 0,10 and 0,62 +/- 0,13 in the fibromyalgia and the healthy group respectively. The mean HGS and shoulder abduction-adduction maximal muscle strength were significantly lower in the fibromyalgia group than the healthy subjects (p<0,001). Whereas a positive correlation was found between HGS and age, BMI and shoulder abduction-adduction maximal muscle strength, a negative correlation was recorded between complaint duration, VAS and FIQ. Conclusion: Hand grip strength may be a simple and effective method to determine muscle performance of the upper extremity.Öğe Treatment of Periodontoid Pannus With Infliximab in a Patient With Rheumatoid Arthritis(LIPPINCOTT WILLIAMS & WILKINS, 2009) Salli, Ali; Sahin, Nilay; Paksoy, Yahya; Kucuksarac, Seher; Ugurlu, Hatice[Abstract not Available]
