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Öğe Acute coronary embolism without valve thrombosis in a patient with a prosthetic mitral valve - Successful percutaneous coronary intervention: A case report(FORUM MULTIMEDIA PUBLISHING, LLC, 2007) Yazici, Mehmet; Kayrak, Mehmet; Turan, Yasar; Koc, Fatih; Ulgen, Mehmet S.We present a 44-year-old female patient with anterior myocardial infarction caused by embolization from mitral valve prosthesis due to inadequate anticoagulation. The patient underwent a cardiac catheterization within the 1st hour of arrival. The angiography showed total occlusion of the left anterior descending coronary artery after the second diagonal branch. Percutaneous transluminal coronary angioplasty and stenting were performed, and coronary artery perfusion was restored. The pain disappeared completely immediately after this intervention. Transthoracic echocardiography shortly after this intervention showed normal prosthetic valve function and no thrombus. Transesophageal echocardiography performed 2 days later revealed no thrombus at the prosthetic valve. In conclusion, this case demonstrated that coronary embolism may occur even without prosthetic valve thrombus or dysfunction with suboptimal International Normalized Ratio levels, and can be successfully treated with percutaneous transluminal coronary angioplasty and stenting.Öğe Complete atrioventricular block associated with rivastigmine therapy(AMER SOC HEALTH-SYSTEM PHARMACISTS, 2008) Kayrak, Mehmet; Yazici, Mehmet; Ayhan, Selim S.; Koc, Fatih; Ulgen, Mehmet S.Purpose. A case of complete atrioventricular block associated with rivastigmine use is presented. Summary. A 67-year-old Turkish woman with Alzheimer's disease was admitted to the hospital because of dizziness and syncope. Her medical history included diagnoses of hypertension (treated with amlodipine 5 mg daily) and diabetes mellitus (treated with nateglinide 120 mg daily). She had been taking both drugs for over five years. She had also been taking rivastigmine 6 mg p.o. daily for five months for the treatment of Alzheimer's disease. She had experienced dizziness since the onset of rivastigmine therapy but had not reported it to any health care provider. On admission, she had a blood pressure measurement of 90/60 mm Hg and a pulse rate of 34 beats/min. A 12-lead electrocardiogram revealed complete atrioventricular block. Echocardiography results, blood electrolyte levels, and cardiac biochemical markers were normal. After initial evaluation, a temporary transvenous pacemaker was implanted via the right femoral vein. Amlodipine and rivastigmine were discontinued. On the first day of hospitalization, a coronary angiogram revealed normal coronary anatomy. Two days later, the complete atrioventricular block resolved spontaneously to sinus rhythm. Rivastigmine 6 mg p.o. daily was reinitiated, and complete atrioventricular block recurred on the fourth day of therapy. A VVI permanent pacemaker was implanted on the fifth day of hospitalization. Amlodipine and rivastigmine were reinitiated. The patient continued rivastigmine 6 mg p.o. daily after permanent pacemaker implantation. A three-month follow-up appointment revealed that no further syncope episodes or dizziness had occurred. Conclusion. A 67-year-old woman developed complete atrioventricular block after receiving rivastigmine for the treatment of Alzheimer's disease.Öğe Completely asymptomatic proximal aortic dissection and massive bullous lung disease: coincidence or is there any etiologic link?(OXFORD UNIV PRESS INC, 2009) Kayrak, Mehmet; Sonmez, Osman; Vatankulu, Mehmet A.; Ulgen, Mehmet S.This case report focuses on a completely asymptomatic proximal aortic dissection in a middle-aged mate smoker with bullous lung disease. The possibility of a relationship between A1-antitrypsin (A1AT) deficiency and aortic dissection is discussed in light of the recent data. (C) 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.Öğe Does Smoking Amplify the Risk of Acute Myocardial Infarction Related with Pregnancy in Factor V Leiden Carriers?(AKAD DOKTORLAR YAYINEVI, 2009) Yazici, Mehmet; Acar, Kadir; Kayrak, Mehmet; Ayhan, S. Selim; Dogan, Umuttan; Ulgen, Mehmet S.[Abstract not Available]Öğe An infective endocarditis case presenting with sudden unilateral loss of vision - the first and single symptom(GALENOS YAYINCILIK, 2007) Soylu, Ahmet; Ulgen, Mehmet S.; Narin, Cueneyt; Soylu, Tuelay[Abstract not Available]Öğe Plasma concentrations of soluble CD40 ligand in smokers with acute myocardial infarction: a pilot study(SPRINGER, 2011) Kayrak, Mehmet; Bacaksiz, Ahmet; Ulgen, Mehmet S.; Vatankulu, Mehmet Akif; Zengin, Kadriye; Ayhan, Selim S.; Basarali, Mustafa KemalCoronary artery disease (CAD) is believed to be the single leading cause of death in both men and women in the world. Smoking is the most important risk factor for CAD. Smoking increases platelet aggregation and thrombus formation. CD40 ligand (CD40L) is a transmembrane glycoprotein derived from activated platelets. It participates in thrombus formation during the acute phase of acute myocardial infarction (MI). Elevation of CD40L identifies the patients who are at highest risk for cardiac events and who are likely to benefit from treatment with the glycoprotein IIb/IIIa (GPIIb/IIIa) receptor antagonists. The purpose of this study was to evaluate levels of CD40L in smokers with acute MI. Fifty-seven patients with acute MI were enrolled in this study. Thirty-one smokers were compared with 26 non-smokers. Soluble CD40L level in the plasma was determined by a standard enzyme-linked immunosorbent assay. Circulating levels of CD40L were higher in the smokers' group. Smokers with acute MI may have increased risk for thrombotic complications during acute MI, and optimal antiaggregant therapy should be administered.Öğe Three-year follow up of recurrent cardiac echinococcosis simulating myxoma: report of a rare case(GALENOS YAYINCILIK, 2007) Ulgen, Mehmet S.; Yazici, Mehmet; Kayrak, Mehmet; Duzenli, M. Akif; Koc, Fatih[Abstract not Available]