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    Myroides sp, a rare opportunistic infective agent, at a hospital in Turkey
    (SOUTHEAST ASIAN MINISTERS EDUC ORGANIZATION, 2019) Kara, Iskender.; Kalem, Fatma.; Unaldi, Ozlem.; Arslan, Ugur.
    Myroides sp is a rare cause of infection, which can be fatal. Myroides spp isolates were obtained from urinal specimens of in- and out-patients attending a hospital in Turkey during July 2015 to November 2017. Myroides sp identification was based on colony morphology, biochemical properties and partial sequence of 16S rDNA, revealing the presence of M. odoratus. Antibiogram profiles showed almost all Myroides sp strains from in-patients (n = 11) were resistant to 13 antibiotics tested except for 50% that were intermediate resistant to tigecycline, whereas strains from out-patients (n = 4) were susceptible or intermediate susceptible. However, all Myroides sp strains lacked the six carbapenem resistance genes examined. Pulse-field gel-electrophoresis demonstrated clonality among four strains from in-patients. Clinical features of five in-patients and two outpatients isolates were believed to be due to Myroides infection and were treated accordingly; however, two died. Two out-patients believed to be infected recovered completely upon treatment. Ten in-patients had renal problems and all outpatients had urological problems or chronic renal failure. Myroides spp caused infection in both immunocompromised and immunocompetent patients in our study. Although tigecycline was used as first line treatment for Myroides-infected in-patients at this hospital, antibiograms of Myroides spp cultured from both in-and out-patients at other hospitals should be maintained to assist in prescribing appropriate antibiotics. Although Myroides infection is rare, its innate multi-drug resistance and propensity among patients with renal and urological problems warrants microbiological attention.