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Öğe ADMA and total oxidant status in saliva(WILEY-BLACKWELL, 2013) Unlu, A.; Taner, A.; Unlu, N.; Ure, Z.; Korucu, E. N.[Abstract not Available]Öğe Association between TSH status and genotypes of E23K polymorphism in KCNJ11 with gestational diabetic individuals(WILEY-BLACKWELL, 2016) Tok, M.; Menevse, E.; Arikoglu, H.; Unlu, A.; Kaya, D. Erkoc[Abstract not Available]Öğe Brefeldin A exerts differential effects on various phenotypes of breast cancer cell lines(WILEY-BLACKWELL, 2016) Tekin, G.; Ozturk, B.; Ozer, E. K.; Bariskaner, H.; Unlu, A.[Abstract not Available]Öğe CLINICAL IMPORTANCE OF B2 GLYCOPROTEIN I ANTIBODIES IN BCR-ABL NEGATIVE MYELOPROLIFERATIVE NEOPLASMS(FERRATA STORTI FOUNDATION, 2016) Kocak, M. Z.; Dagli, M.; Kutlucan, A.; Basturk, A.; Unlu, A.; Acar, H.; Kutlucan, L.[Abstract not Available]Öğe The Effect of Diazepam on the Development of Neural Tube Defects in Early Chick Embryos(Turkish Neurosurgical Society, 1999) Guney, O.; Selcuki, M.; Unlu, A.; Bagdatoglu, C.This study reveals the effects of diazepam on the development of neural tube defects in the chick based on light microscopy and histopathological study. Thirty fertile Hubbard Broil eggs were divided into two equal groups. Group 1 embryos (n:15) at Stage 8 (the four-somite stage) of development were explanted and grown for 18 hours in nutrient medium (thin albumin). Group 2 embryos (n:15) at Stage 8 (four-somite stage) of development were explanted and grown for 18 hours in nutrient medium containing 400 ?g/ml Diazepam. After the incubation period, 86.6% of the control embryos (Group 1) had intact neural tubes, and 80% of the Group 2 embryos showed neural tube defects. The results of this study suggest that Diazepam causes neural tube defects.Öğe Integrated miRNA profiling of estrogen receptor-positive breast cancer cell MCF-7(WILEY-BLACKWELL, 2015) Bozkurt, S. B.; Ozturk; Kocak, N.; Unlu, A.[Abstract not Available]Öğe Metastin levels in relation with hormonal and metabolic profile in patients with polycystic ovary syndrome(ELSEVIER SCIENCE BV, 2014) Yilmaz, S. A.; Kerimoglu, O. S.; Pekin, A. T.; Incesu, F.; Dogan, N. U.; Celik, C.; Unlu, A.Objective: The aim of the present study was to evaluate serum concentrations of metastin in relation with hormonal and metabolic profile in patients with and without polycystic ovary syndrome (PCOS). Study design: The study was a clinical study. Eighty-three women with PCOS and 66 body mass index (BMI) matched controls were divided into two groups, based on BMI: overweight and obese (BMI >= 25 kg/m(2)) and normal weight. (BMI < 25 kg/m(2)) Hirsutism scores, hormonal and metabolic profile as well as metastin levels were evaluated in each subject. Blood samples were collected in the early follicular phase (between day 2 and day 5 of the menstrual cycle) at 9:00 AM, after an overnight fast. Circulating levels of LH, FSH, PRL, TSH, T, fT, DHEAS, 17-OH-P, sex hormone-binding globulin (SHBG), insulin, glucose, lipid profile and metastin were measured. Results: Metastin levels were significantly higher in the PCOS group compared to controls (2.02 ng/ml versus 1.16 ng/ml, p < 0.001). Metastin levels correlated significantly positively with luteinizing hormone (LH), total testosterone (T), dehydroepiandrosteronesulphate (DHEA-SO4) levels, modified Ferriman-Gallwey (mFG) scores and free androgen index (FAI); however, correlated negatively with sex hormone binding globulin (SHBG) levels (p < 0.05). When overweight or obese (BMI >= 25 kg/m(2)) and normal weight (BMI < 25 kg/m(2)) women with PCOS were compared to body mass index (BMI) matched controls, higher metastin levels were also found in PCOS groups (1.94 ng/ml versus 1.18 ng/ml, and 2.06 ng/ml versus 1.08 ng/ml, p < 0.05, respectively). Conclusions: These findings suggest that metastin levels were higher in women with PCOS as compared to controls regardless of BMI. Furthermore, metastin levels can be used as a specific marker for androgenic profile and this marker might play a role in the pathogenesis of PCOS. (C) 2014 Elsevier Ireland Ltd. All rights reserved.Öğe Metastin levels in relation with hormonal and metabolic profile in patients with polycystic ovary syndrome -- 2(OXFORD UNIV PRESS, 2014) Yilmaz, S. A.; Kerimoglu, O. Secilmis; Pekin, A.; Incesu, F.; Dogan, N. U.; Celik, C.; Unlu, A.[Abstract not Available]Öğe MMP-9 and TIMP-1 levels in the sputum of patients with chronic obstructive pulmonary disease and asthma(BLACKWELL PUBLISHING, 2006) Unlu, A.; Calikoglu, M.; Gun, D.; Ayaz, L.; Tamer, L.[Abstract not Available]Öğe Relationship Between ADMA Levels and chronic obstructive pulmonary disease progression(BLACKWELL PUBLISHING, 2007) Erdem, S.; Unlu, A.; Kanat, F.[Abstract not Available]Öğe Vitamin D serum levels in children with allergic rhinitis(WILEY-BLACKWELL, 2015) Artac, H.; Ozdemir, H.; Unlu, A.; Bozkurt, M. K.; Bozkurt, B.[Abstract not Available]
