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    Antibacterial activity of new [(2-hydroxypropyl)-n-oximino]pyridines
    (ASIAN JOURNAL OF CHEMISTRY, 2008) Sen, Nejdet; Kar, Yakup; Kurbanov, Sultan; Uyanik, Arzu
    The synthesized [(2-hydroxypropyl)-n-oximino]pyridine derivatives has been tested against the pathogenic four Gram-positive bacteria Bacillus cereus (ATCC 11778), Staphylococcus aureus (ATCC 6538), Sarcina lutea (ATCC 934 1) and Streptococs mutans (UCTC 10499) and three Gram-negative bacteria Salmonella typhimurium (1,4,5,12:;: 1,2), Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (ATCC 29998). Generally, all synthesized compounds (IVa-c) showed strong activity compared to antibiotic drug (cefalexin). However, among this compounds (IVa) showed excellent activity against Bacillus cereus (ATCC 11778), Sarcina lutea (ATCC 9341), Salmonella typhimurium (1,4,5,12:;: 1,2) and Escherichia coli (ATCC 29998) compared to cefalexin.