Yazar "Uysal, II" seçeneğine göre listele

Listeleniyor 1 - 5 / 5
  • Küçük Resim Yok
    Öğe
    Correlation between developmental stages of the human heart and gestational ages
    (SAUDI MED J, 2005) Uysal, II; Karabulut, AK; Salbacak, A; Buyukmumcu, M; Seker, M
    Objectives: In this study we aimed to investigate the normal developmental pattern of the human fetal heart in second and third trimester, and to evaluate the correlation of the values with the gestational age (GA). Methods: Seventy spontaneously aborted human fetuses with no external malformations were investigated and 11 parameters from each were assessed. The relationship of these parameters with the GA was evaluated by linear regression and correlation analyses using statistical methods. In addition, the values were compared to the gender and sides of the heart using Student t-test. This study was performed at the Department of Anatomy, Meram Medical Faculty, Selcuk University, Konya, Turkey, during the period from 2000 to 2004. Results: There was a statistically significant linear relationship between the heart wall thicknesses, the development of the valves of the heart and GA. The mean values of the right side of the heart were found to be higher than those of the left side, and differences were statistically significant (p < 0.05). Although, most of the parameters were found to be higher in females, only 2 of them were statistically significant. All parameters of the cardiac valves measured were significantly higher in the second trimester. There was no difference regarding the correlation ratio of the trimesters between the pulmonary valve diameter and GA. The measurement of the cardiac valves did not show any differences regarding the gender. Conclusion: This study presents the normal values of the development of the fetal heart in second and third trimester that may provide useful background information for clinical approaches.
  • Küçük Resim
    Öğe
    An investigation of non-depolarizing muscle relaxants on embryonic development in cultured rat embryos
    (LIPPINCOTT WILLIAMS & WILKINS, 2004) Karabulut, AK; Reisli, R; Uysal, II; Celik, JB; Ziylan, T
    Background and objective: We have investigated the toxic and teratogenic effects of certain non-depolarizing muscle relaxants on embryonic development in cultured rat embryos. Methods: Rat embryos of 9.5 days were explanted and cultured in vitro for 48 h in rat serum. Whole rat serum was used as a culture medium for the control group while different concentrations of atracurium, cis-atracurium, rocuronium and mivacurium were added to rat serum for the experimental groups. Dose-dependent effects of these agents on embryonic developmental parameters were compared using morphological and biochemical methods. Each embryo was evaluated for the presence of any malformations. Results: When compared to the control embryos, the muscle relaxants significantly decreased all growth and developmental parameters dose dependently with an increase in overall dismorphology. Among these malformations, maxillary deformity was most frequently observed. These effects were observed in much lower doses with atracurium and cis-atracurium compared to those with rocuronium and mivacutium. Conclusions: Our results suggest that non-depolarizing muscle relaxants cause dose-dependent toxicity on rat embryos at concentrations much greater than those in clinical practice. Although, these agents seems to have a low potential for causing developmental toxicity during organogenesis, because of the lower toxic effects observed with rocuronium and mivacurium, these agents may be preferred when recurrent administrations are necessary for parturients.
  • Küçük Resim
    Öğe
    Possibility of middle meningeal artery-to-petrous internal carotid artery bypass: An anatomic study
    (THIEME MEDICAL PUBL INC, 2004) Ustun, ME; Buyukmumcu, M; Seker, M; Karabulut, AK; Uysal, II; Ziylan, T
    The possibility of creating a middle meningeal. artery (MMA)-to-petrous internal carotid artery (ICA) bypass was investigated in si cadavers (bilaterally). Such a procedure could be used to treat patients with high cervical vascular lesions and those with tumors of the infratemporal fossa invading the high cervical ICA. After a frontotemporal craniotomy, the foramen spinosum and foramen ovale were exposed extradurally. Immediately posterior to the foramen ovale and medial to the foramen spinosum, the petrous portion of the ICA was exposed with a diamond-tipped drill. The MMA was lifted from its groove, and a sufficient length was transected to perform a bypass with the petrous ICA medially. The mean width of the MMA at the site of anastomosis was 2.3 +/- 0.35 mm. The mean length of MMA from the foramen spinosum to the site of the anastomosis was 9.6 +/- 1.7 mm. Based on these measurements, width and length of MMA appear to be sufficient for a bypass with petrous ICA.
  • Küçük Resim
    Öğe
    A rare variation of the coeliac trunk
    (URBAN & FISCHER VERLAG, 2005) Cicekcibasi, AE; Uysal, II; Seker, M; Tuncer, I; Buyukmumcu, M; Salbacak, A
    The hepatic, splenic and left gastric arteries are considered as the "main classic branches" of the coeliac trunk. During the routine dissections in the laboratory of the Anatomy Department in a 62-year-old mate cadaver, a rare variation, a coeliacomesenteric trunk was observed. This trunk gave rise to the left gastric, the common hepatic, the splenic, the left gastro-epiploic, the right and Left inferior phrenic arteries. The developmental and clinical significance of this anomalous vessel is discussed. (c) 2005 Elsevier GmbH. All rights reserved.
  • Küçük Resim
    Öğe
    Superficial temporal artery graft for bypass of the maxillary to proximal middle cerebral artery using a transantral approach: an anatomical and technical study
    (TAYLOR & FRANCIS AS, 2005) Arbag, H; Cicekcibasi, AE; Uysal, II; Ustun, ME; Buyukmumcu, M
    Conclusion. Using a transantral approach, we examined a new bypass of the maxillary artery ( MA) to proximal middle cerebral artery ( MCA). The caliber of the MA was suitable to provide sufficient blood flow. The length of the graft was shorter and it had a straighter course in the new technique than in previously described techniques. Objective. To examine a new bypass of the MA to proximal MCA using a transantral approach as an alternative to other forms of anterior circulation bypass surgery. Material and methods. The method was applied to five adult cadavers bilaterally. The MA and its branches were easily found after removal of the posterior sinus wall using a transantral approach. Then, a hole was created in the sphenoid bone 5 - 6 mm lateral to the posteroinferior edge of the superior orbital fissure extradurally. After the carotid and sylvian cisternae had been opened, the M2 segment of the MCA was exposed. The MA was transected just before the origin of the descending palatine artery branch. After opening the dura over the hole, the MA was passed through the hole to reach the intracranial cavity. The proximal side of the superficial temporal artery graft was anastomosed end- to- end with the MA and the distal side was anastomosed end- to- side with the M2 segment of the MCA. Results. The mean caliber of the MA was 2.4 +/- 0.3 mm before the origin of the descending palatine artery branch. The mean caliber of the largest trunk of the M2 segment of the MCA was 2.3 +/- 0.3 mm. The average length of the graft was 24 +/- 3 mm.