Yazar "Uytun, Merve Cikili." seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Parent-reported social problems and clinician-evaluated adverse effects may be differentially affected by differing extended release methylphenidate formulations: a prospective, naturalistic study from Turkey
    (TAYLOR & FRANCIS LTD, 2019) Uytun, Merve Cikili.; Cetin, Fatih Hilmi.; Babadagi, Zehra.
    OBJECTIVE: Medikinet retard (R) is a nonosmotic, extended-release formulation of Methylphenidate (MPH) and has been used in Turkey for the last 4-5 years. The aim of our study is to compare the efficacy on functionality of Medikinet retard (R) and Concerta (R) and their adverse events. METHODS: Participants were referred to the Kayseri Training and Research Hospital and followed up there between August 2016 and June 2018. This study design is a 16-week prospective trial, each child received 16 weeks of OROS-MPH or MPH-ER. A total of 103 children were enrolled in the study, but only 70 children (n = 35 concerta, n = 35 medikinet retard) completed the study. Weiss Functional Impairment Rating Scale-Parent Report Form (WFIRS-P) and Barkley Side Effect Rating Scale (BSERS) were used for assessment. RESULTS: In both treatment groups, children improved significantly over time, both in intensity and in the number of problems. Regarding the social problems, Medikinet retard (R) was superior to the Concerta in terms of effects. The side effects of insomnia and euphoria were seen more common in the Concerta (R) group than the Medikinet retard (R). Additionally, the mean severity scores of euphoria were shown higher in the Concerta (R) group than the Medikinet retard. CONCLUSION: From this study, we concluded that Medikinet retard (R) is also an effective and safety MPH formulation.
  • Küçük Resim
    Öğe
    Romatizmal kalp hastalığı olan çocuk ve ergenlerde psikiyatrik problemler ve bunları etkileyen faktörler: Bir ön çalışma
    (GALENOS YAYINCILIK, 2019) Uytun, Merve Cikili.; Çelik, Serkan Fazlı.; Çetin, Fatih Hilmi.; Babadağı, Zehra.; Uytun, Salih.
    INTRODUCTION: We aimed to evaluate the psychiatric symptoms in addition to quality of life in children and adolescents with rheumatic heart disease, and to determine which factors contribute to psychiatric problems of them. MATERIALS and METHODS: A total of 25 children and adolescents with rheumatic heart disease, additionally, 25 children and adolescents with typical developing controls aged 6-16 years old were included. Kiddie-Schedule for Affective Disorders and Schizophrenia, (present and life time version - K-SADS-PL) was applied to parents of all of the children and adolescents, and Child Depression Inventory, The Spielberger State-Trait Anxiety Inventory for children KINDLR Questionnaire for Measuring Health-Related Quality of Life in Children and Adolescents were applied to all of the children and adolescents. Assessment for mothers, Beck Depression Inventory, Beck Anxiety Inventory and Five Factor Personality Inventory were used. RESULTS: We found higher anxiety scores and increased anxiety disorder diagnosis among children and adolescents with rheumatic heart disease (p<0.05). Mothers' anxiety scores, depression scores, and personality traits are associated with KINDL subscales, and neuroticism scores are also associated with Child Depression Inventory scores. In addition, presence of psychiatric disorder was predicted by Beck anxiety scores. CONCLUSIONS: Our results suggest that psychiatric evalution is important in the treatment of children and adolescents and their parents with rheumatic heart disease.