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Öğe Atypical middle lobe and lingula involvement in kerosene pneumonitis(INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D), 2004) Kanat, F; Vatansev, H; Ozer, F; Imecik, O[Abstract not Available]Öğe Effects of glutamine in critical illness(SAUDI MED J, 2005) Cander, B; Kalkan, E; Kaymakci, A; Koylu, R; Vatansev, H; Bulun, EObjectives: Under normal physiological conditions, glutamine is synthesized in large amounts by the human body and is considered nonessential. It has been hypothesized that glutamine may become a conditionally essential amino acid in patients with catabolic disease. The objective of this study is to investigate the prognostic effect of glutamine. Methods: Fort this study, we selected 48 patients from the intensive care unit. Group I consisted of 33 patients whose treatment included glutamine. We placed the remaining 15 patients in group 11, and they did not receive glutamine in their treatment. We retrospectively investigated treatment time, leucocyte levels and outcome. We carried out the study between January 2002 and January 2003 in Konya Governmental Hospital, Turkey. Results: The average duration of hospital stay in the glutamine group was 8 +/- 1.2 days, 58% of them leaving hospital with surrogate. However, in the group whose treatment did not include glutamine, 42% of them left the hospital surrogate, their average hospital stay being 12 3 days. In the group receiving glutamine in the treatment, there was a prominent decrease in leukocyte levels compared to the other group, and hospitalization times were shorter but there was no statistically significant difference in mortality or survival rates. Conclusions: Glutamine may decrease the catabolism. it may also have a positive effect on treatment time and the consequences of therapy in critically ill patients.Öğe Investigation of lipid peroxidation and activities of glutathione peroxidase and superoxide dismutase in serum and leukocyte of patients with leukemia.(AMER SOC HEMATOLOGY, 1999) Bahçeci, S; Akkuş, İdris; Gültekin, Fatih; Vatansev, H; Çağlayan, O[Abstract not Available]Öğe Oxidative stress in childhood obesity(FREUND PUBLISHING HOUSE LTD, 2004) Atabek, ME; Vatansev, H; Erkul, IObjective: To measure products of free radical damage in childhood obesity. Methods: Plasma free radicals were assayed in 24 children with exogenous obesity and 24 non-obese healthy controls. A new colorimetric method was used that measures the generation of peroxy radicals (D-Roms), first products of the reaction between free radicals and oxygen. Results: D-Roms levels were higher in the obese children than in the non-obese group (33.3 +/- 10.1 mg% of H2O2 vs 22.8 +/- 2.8 mg% of H2O2; p < 0.001). Moreover, D-Roms levels were higher in children with hyperlipidemia than in children with normolipidemia (49.6 +/- 3.1 mg% of H2O2 vs 27.8 +/- 3.2 mg% of H2O2; p < 0.001). D-Roms level was positively correlated with waist-hip ratio, serum total cholesterol, serum triglycerides, serum low-density lipoprotein-cholesterol, systolic blood pressure, diastolic blood pressure and fasting blood glucose in obese children. In a multivariate regression model for obese children, the independent correlates for D-Roms level were systolic blood pressure (p < 0.001) and serum total cholesterol (p < 0.001), with the total variance explained being 82%. Conclusion: Our study demonstrates for the first time that there was increased D-Roms levels in ob se children and adolescents and suggests that increased systolic blood pressure associated with hyperlipidemia may independently contribute to increased oxidative stress in childhood obesity.Öğe Testosterone secretion and semen plasma enzyme activity in rams with genital pathology stimulated with GnRH(ELSEVIER SCIENCE INC, 2002) Aksoy, Melih; Kaya, A; Vatansev, H; Tekeli, TTestosterone secretion in response to GnRH stimulation and enzymatic activity of semen plasma was evaluated comparatively in rams with or without genital abnormality. Scrota. testes and epididymides of 128 rams between 1.5 and 6 years old from various breeds were examined clinically and ultrasonographically. Bilaterally cryptorchid rams (n = 2), and rams with focal testicular degeneration (n = 3) or unilateral sperm granuloma localized in the caput (n = 3) epididymis or the cauda epididymis (n = 3). diagnosed by either clinical or ultrasonographic examination. were selected for the further investigation of spermatologic parameters, testosterone secretion in response to GnRH stimulation. and enzymatic activity of semen plasma before histopathologic confirmation of lesions. Except for the cryptorchid rams, sperm parameters determined in ejaculates were similar to intact controls (n = 3). GnRH administration increased plasma testosterone levels significantly irrespective of the type of genital pathology (P < 0.01). The testosterone response calculated based on area under the curve following GnRH administration in rams having genital abnormality was not significantly different from the controls. Aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) activity in the semen plasma varied between rams. with the lowest mean values in the bilaterally cryptorchid group (P < 0.05). Spermatic granuloma localized either in the caput or cauda of the epididymis was associated with a significant reduction in the semen plasma AST activity compared to controls (P < 0.01). In conclusion, our results indicated that the ability of testicular tissue to secrete testosterone in response to GnRH stimulation in rains with bilateral cryptorchidisin, focal testicular degeneration and unilateral sperm granuloma was similar to that of intact controls. and that reduced semen plasma AST activity may have a diagnostic value in the diagnosis of the epididymal obstruction in rams. Focal testicular degeneration did not influence AST, alkaline phosphatase (ALP) and LDH activity in semen plasma. (C) 2002 Elsevier Science Inc. All rights reserved.
