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Öğe Bir beyaz leylekte (Ciconia ciconia) Lucilia sericata (Diptera: Calliphoridae) kaynaklı travmatik myiasis olgusu(Selçuk Üniversitesi Veterinerlik Fakültesi, 2018) Yaman, Mehmet; Zerek, Aykut; Akküçük, ŞerifeMustafa Kemal Üniversitesi, Veteriner Fakültesi Kliniğine yaralanma şikâyeti ile getirilen bir beyaz leyleğin muayenesinde, sol kanadında açık humerus kırığına ve kırık kemik içerisinde sinek larvalarına rastlandı. Toplanan larvalar, anterior ve posterior stigmalara ve sefalo-faringeal iskeletin morfolojik özelliklerine bakılarak teşhis edildi. Yapılan mikroskobik muayene sonucun-da larvaların Lucilia sericata’nın üçüncü dönem larvası olduğu tespit edildi. Literatür bilgilere göre beyaz leyleklerde travmatik miyaz vakaları az görülmektedir. Bu çalışmada Hatay ilinde bir beyaz leylekte L. sericata kaynaklı travmatik miyaz vakası bil-dirilmiştir.Öğe Culicoides species (latreille, 1809) (diptera: ceratopogonidae) in Hatay province(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2010) Dik, Bilal; Yaman, Mehmet; Uslu, UgurThis study was carried out to determine of Culicoides species in Hatay province (Antakya, Reyhanli, Hassa, Samandag and Kirikhan districts) between April 2005 and October 2006. The light traps were used for the collection of Culicoides samples. They were placed in or nearby sheep or cattle pens at the sunset and was kept for about two-three hours. A total of 520 Culicoides specimens were collected and 15 species were identified follow as: C. badooshensis Khalaf. C. cataneii Clastrier. C. circumscriptus Kieffer. C. dzhafarovi Remm. C. festivipennis Kieffer. C. gejgelensis Dzhafarov. C. imicola Kieffer. C. nubeculosus (Meigen), C. odiatus Austen, C. picturatus Kremer and Deduit, C. puncticoffis (Becker), C. riethi Kieffer. C. sahariensis Kieffer. C. schultzei kompleks (Enderlein). C. shaklawensis Khalaf. While Culicoides circumscriptus and C. schultzei kompleks were dominant species, two specimens of C.f estivipennis. C. odiatus. C. picturatus. C. riethi and C. shaklawensis only one specimen of C. dzhafarovi were obtained.Öğe Does Botox effect neural tube development in early chick embryos?(SPRINGER, 2007) Eser, Olcay; Yaman, Mehmet; Cosar, Emine; Konak, Abdullah; Cosar, Murat; Sahin, Oender; Gueney, OenderBotulinum toxin (BTX) is a potent neurotoxin produced by Clostridium botulinum and has wide usage in different areas. The current study aimed to analyze the effects of C. botulinum toxin on the central nerve system in chick embryos. Forty fertile Hubbard Broil eggs, all at Stage 8 of development, were divided into four equal groups: Group 1 embryos (n=10), the control group, were explanted and grown for 18 h in a nutrient medium (thin albumin). Group 2 embryos (n=10) were grown in medium containing 5 U BTX, Group 3 embryos (n=10) in a medium containing 10 U BTX and Group 4 embryos (n=10) in medium containing 20 U BTX. After the incubation period, 80% of Group 1 and 2 embryos and 90% of Group 3 and 4 embryos had intact neural tubes (P > 0.05). The results of this study suggest that BTX had no additional effect on neural tube development in early chick embryos.Öğe The evaluation of protective effects of FK-506 on neural ischemic-reperfusion injury: an experimental study(SPRINGER HEIDELBERG, 2007) Eser, Olcay; Kalkan, Erdal; Cosar, Murat; Yaman, Mehmet; Buyukbas, Sadik; Avunduk, Mustafa Cihat; Fidan, HueseyinObjective: In this study, we aimed to delineate the mode of neuroprotective action of FK-506, and demonstrated that FK-506 could decrease oxidative stress and apoptotic cell death in an in vivo rat model of neural ischemia-reperfusion after hemorrhagic shock. Methods: Thirty rats were used as experimental subjects and divided into five equal groups. Group A rats (sham group, n = 6) were anesthetized and craniotomies were performed for collecting brain tissue samples. In group B ischemia-reperfusion (I/R + 1 h, n = 6), group C (I/R + 24 h, n = 6), group D (I/R + 1 h FK-506, n = 6) and group E (I/R + 24 h FK-506, n = 6), systolic blood pressure of the rats decreased to 40-50% of the normal level via bleeding from the femoral vein. Thus, a hemorrhagic shock and ischemic neural tissue model was formed. The blood was retained and given to the remaining animals in groups B, C, D and E via femoral vein for reperfusion 20 min after the procedure. In group D and E, 1 mg/kg FK-506 in 0.5 ml isotonic solution was administered to the rats 5 min before reperfusion. Group B and D rats were sacrificed after 1 hand group C and E rats were sacrificed 24 h after reperfusion; the rats were sacrificed via bleeding associated with intracardiac puncture. Craniotomy was also performed in groups B, C, D and E and brain tissue samples were fixed using neutral buffered 10% formaldehyde solution for immunohistopathological examination as in group A. Brain tissue superoxide dismutase (SOD) activities, malondialdehyde (MDA) levels, tissue myeloperoxydase (MPO) activities and apoptotic cell analyses with APO 2.7 immunohistochemically were also performed in all groups. Results: The result of the study revealed that the SOD activities were lower for groups B (I/R + 1 h) and C (I/ R + 24 h) than for group A (sham group) (p < 0.05). In addition, SOD activities were higher in groups D (I/ R + 1 h FK-506) and E (I/R + 24 h FK-506) than in groups B (I/R + 1 h) and C (I/R + 24 h) (p < 0.05). MDA levels, MPO activities and the number of apoptotic cells were lower in group A (sham group) than in groups B (I/R + 1 h) and C (I/R + 24 h) (p < 0.05). In addition to these MDA levels, MPO activities and the number of apoptotic cells were higher in groups B (I/R + 1 h) and C (I/R + 24 h) as compared to groups D (I/R + 1 h FK-506) and E (I/R + 24 h FK-506) (p < 0.05). Conclusion: The results suggest that the prophylactic use of FK-506 in an in situ ischemic neural tissue may prevent reperfusion injury.Öğe The first case of bovicola (werneckiella) ocellatus (piaget, 1880) (phthiraptera: ischnocera: trichodectidae) on a donkey (equus asinus linnaeus, 1758) in Turkey(ANKARA UNIV PRESS, 2020) Dik, Bilal; Erdem, Ipek; Zerek, Aykut; Karagoz, Mustafa; Yaman, MehmetIn the clinical examination of a donkey, which brought to the Ownerless Animal Care and Rehabilitation Center of the Hatay Metropolitan Municipality due to neglecting and senility, local hair losses, ruffling and opacity were observed. A few louse specimens were detected on the hair shafts on the back of the donkey during the macroscopic examination. They were collected with a forceps, and preserved in a tube with alcohol 70%. Then they examined in detail in microscope, and identified as Bovicola ocellatus (Piaget, 1880). The presence of B. ocellatus on donkey has been reported for the first time in Turkey in this paper.Öğe Hindilerde (Meleagris Gallopavo) Bağırsak Parazitlerinin Yayılışı(Selçuk Üniversitesi, 2000) Sevinç, Ferda; Güçlü, Feyzullah; Altınöz, Funda; Yaman, MehmetThis study was carried out on domestic turkeys in Central villages of Konya between August 1996- December 1999. Macroscopic examination of whole gastrointestinal system of 40 turkeys and microscopic examination of the fecal samples of 450 turkeys were performed. Various parasite species were determined in 52.5 % of turkeys Eimeria sp., Heterakis gallinarum, Subulura differens, Echinostoma revolutum, Ascaridia galli were respectively detected at the rate of 37.5%, 15%, 7.5%, 5%, 2.5% in the macroscopic examination of gastrointestinal system. The fecal samples were examined by the Fullebome's salt saturated flotation and Benedek sedimentation methods, and in 111 (24.66 %) of fecal samples were found to be parasitised. Eimeria sp oocysts, Capillaria sp., Ascardia sp. Choanotaenia infundibulum, Trichostrongylus tenuis and Heterakis gallinarum eggs were respectively detected at the rate of 12.88 %, 7 11 %, 6.44 %, 1.55 %, 1.33 %, 0.88 %in the microscopic examination of fecal samples.Öğe The influence of dexmedetomidine on ischemic rat hippocampus(ELSEVIER SCIENCE BV, 2008) Eser, Olcay; Fidan, Huseyin; Sahin, Onder; Cosar, Murat; Yaman, Mehmet; Mollaoglu, Hakan; Songur, AhmetIn our study, we evaluated the neuroprotective effects of dexmedetomidine on oxidantantioxidant systems, pro -inflammatory cytokine TNF-a and number of apoptotic neurons on hippocampus and dentate gyrus after transient global cerebral I/R injury. Eighteen rats divided into 3 groups, equally. Group I rats were used as shams. For group II and III rats, they were prepared for transient global cerebral ischemia using a four-vessel- occlusion model. 5 mL/kg/h 0.9% sodium chloride was infused to the Group II and 3 Pg/kg/h/5 ml dexmedetomidine was infused to the Group III for 2 h after I/R injury. The levels of MDA and NO and activities of SOD and CAT were measured in the left hippocampus tissue. The levels of TNF-a concentration were measured in the plasma. The number of apoptotic neurons was counted by TUNNEL method in histological samples of right hippocampus tissue. MDA and NO levels increased in Group II compared with Group I rats (p=0.002, p=0.002, respectively). In group III, MDA and NO levels decreased as compared to Group 11 (p=0.015, p=0.002, respectively). SOD and CAT activities increased in Group III as compared to Group II rats (p = 0.002, p = 0.002, respectively). The decrease in TNF-a levels of group III was significant as compared to group II (p=0.016). The number of apoptotic neurons in group III was lower than Group II rats. Our study showed that dexinedetomidine has a neuroprotective effect on hippocampus and dentate gyrus of rats after transient global cerebral I/R injury. (c) 2008 Elsevier B.V. All rights reserved.Öğe Kelam'da günah ve tevbe(Selçuk Üniversitesi Sosyal Bilimler Enstitüsü, 2006) Yaman, Mehmet; Özbek, DurmuşDini emir ve yasaklara karşı gelme ve yaratıcıya başkaldırmanın ortak adı olan günah ve insanı bu günahlardan arındıracak olan da tevbedir. Günah ve tevbe ilk insan Hz. Adem'den bu güne insanoğlunun kaçınılmaz bir olgusudur. Bu çalışma, Günah ve Tevbe kavramlarını nasslar çerçevesinde Kelâmû açıdan ele almak, insan üzerindeki etkilerini inceleyerek bu alanda bir araştırmanın ilk adımını atmayı amaçlamaktadır. Giriş bölümünde günah ve tevbenin; sözlük ve terim anlamları tanıtılmış ve ardından günah-tevbe ilişkisi ortaya konmuştur.Birinci bölümde günah ve tevbenin tarifleri yapıldı. Kur'an'da konuların nasıl ifade edildiği üzerinde durularak dini mesnedleri ortaya konulmuştur. Günah çeşitleri, insanın günah işleme esnasındaki durumları ve Tevbe çeşitleri, kâmil tevbede olması gereken hususlar ortaya konmaya çalışılmıştır. kinci bölümde ise mevzuya Kelamcılar açısından bakılmış Kelâmcıların günah ve tevbe anlayışları ortaya konmaya çalışılmıştır. Konunun fıkıh ve tasavvuf yönleri kendi sahalarına bırakılmıştır. Çalışmamız neticesinde günah ve tevbenin hem fert hem toplum hayatında büyük bir öneme haiz olduğu müşâhade edilmiş; günah işleyen insanların tevbe ile yeniden huzura kavuştuğu ve tevbe ile affedilmeyecek hiçbir günahın (kul hakkı hariç) olmadığı sonuçlarına ulaşılmıştır.Öğe The protective effect of avocado soybean unsaponifilables on brain ischemia/reperfusion injury in rat prefrontal cortex(TAYLOR & FRANCIS LTD, 2011) Eser, Olcay; Songur, Ahmet; Yaman, Mehmet; Cosar, Murat; Fidan, Huseyin; Sahin, Onder; Mollaoglu, HakanObject. We investigated the protective effects of avocado/soybean unsaponifiables (ASU) on the prefrontal cortex (PFC) after global brain ischemia/reperfusion (I/R) injury in rats. Methods. Rats were randomly divided into three experimental groups as follows: Group I was control rats, Group II was ischemia rats, Group III was Isch+ASU rats. Brain ischemia was produced via four-vessel occlusion model. These processes followed by reperfusion for 30 min for both II and III groups. Rats were sacrificed and their brains were removed immediately. Malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in left PFC, levels of TNF-alpha concentration were measured in the plasma. The number of apoptotic neurons was assayed in histological samples of the right PFC. Results. MDA and TNF-alpha levels as well as the number of apoptotic neurons were observed to have decreased significantly in Group III compared to Group II, while SOD activities have been found to have increased significantly in Group III in comparison to Group II, significantly. Conclusions. We think that ASU might have an antioxidant and neuroprotective effects in brain I/R injured rats.
