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Öğe A Multi-Institutional Analysis for Sequential Adjuvantchemotherapy and Radiation Versus "Sandwich" Multi-Modality for STAGE IIIC Endometrial Carcinoma(ELSEVIER SCIENCE INC, 2018) Önal, C.; Sarı, S. Yüce; Yıldırım, B. Akkuş; Yavaş, G.; Gültekin, M.; Güler, O. C.; Akyürek, Serap[Abstract not Available]Öğe Postmastectomy radiation therapy in locally advanced breast cancer(2013) Yavaş, G.; Yavaş, C.; Akyürek, S.Despite wide efforts for early detection of breast cancer using screening mammography, locally advanced breast carcinomas account for a remarkable proportion of all breast carcinomas, particularly in developing countries. Locally advanced breast cancer may have widely different clinical and biological features. Radiotherapy plays an important role in the management of locally advanced breast cancer. Postmastectomy radiotherapy has been shown to significantly reduce the risk of loco-regional failure and to improve disease free survival as well as overall survival in high-risk women with breast cancer. This review article summarizes the data from randomized trials revealing a significant benefit from postmastectomy radiation therapy in patients with locally advanced disease. Copyright © Experimental Oncology, 2013.Öğe Radiation Therapy and Chemotherapy Results in Elderly Patients With Stage III Non-Small Cell Lung Cancer: Turkish Thoracic Radiation Oncology Group Study(ELSEVIER SCIENCE INC, 2016) Akyürek, Serap; Özdemir, B. S.; Sert, F.; Yalman, D.; Yavaş, G.; Cengiz, M.; Bakkal, H.[Abstract not Available]Öğe Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer(2013) Akyürek, S.; Yavaş, G.Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy. There are several advantages of administering neoadjuvant chemotherapy: tumor downstaging, improving the chance of breast conserving surgery, in vivo assessment of tumor sensitivity to the chosen therapeutic regimen, and early control of micro-metastatic disease. However there are substantially less data to aid in determining which patients treated with neo-adjuvant chemotherapy warrant postmastectomy radiotherapy. According to the recent literature, patients who require mastectomy after systemic therapy should receive postmastectomy radiotherapy. Copyright © Experimental Oncology, 2013.Öğe Serum human epididymis protein 4 is associated with the treatment response of concurrent chemo-radiotherapy and prognosis in patients with locally advanced non-small cell lung cancer(SPRINGER-VERLAG ITALIA SRL, 2018) Yavaş, G.; Yavaş, C.; Akyürek, S.[Abstract not Available]