Kulak, Burun ve Boğaz Hastalıkları/Makale Koleksiyonu

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https://hdl.handle.net/20.500.12395/39310

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Tonsillektomi Yapılan Erişkin Hastalarda Dil Basacağına Bağlı Ortaya Çıkan Dil Ödeminin Ultrasonografi ile Değerlendirilmesi: Prospektif, Paralel Grup, Klinik Çalışma
(Selçuk Üniversitesi, 2021 Eylül) Elsürer, Çağdaş
Amaç: Tonsillektomi cerrahisi, Kulak Burun Boğaz (KBB) pratiğinde en sık yapılan cerrahi işlemlerden biridir. Ameliyat sırasında cerrahın görüş alanını arttırmak için kullanılan ağız açacağı ve dil basacağı, hastanın dil dokusuna yüksek basınç uygulayarak çeşitli komplikasyonlara neden olabilir. Bu çalışmanın amacı, tonsillektomi yapılan erişkin hastalarda, cerrahi esnasında kullanılan dil basacağının dil üzerinde oluşturduğu basınca bağlı olarak gelişmesi muhtemel dil ödeminin, ultrasonografi (USG) ile araştırılmasıdır. Gereç ve yöntem: Çalışmaya 18-40 yaş arası hastalar dahil edildi ve iki gruba ayrıldı. Çalışma grubu (n = 31), KBB kliniğinde tonsillektomi yapılan hastalardan oluşmakta iken kontrol grubu (n = 30), genel anestezi altında tonsillektomi dışında başka bir cerrahi yapılan, dil dokusuna herhangi bir baskı uygulanmayan ve genel anestezi süresi, tonsillektomi cerrahisinin süresine yakın olan hastalardan oluşturuldu. Her hastanın, submental koronal plan Ultrasonografi (USG) ile dil kesit alanı (TA) iki defa ölçüldü. Çalışma grubunda ilk ölçüm (TA1) endotrakeal entübasyondan hemen sonra, ancak ağız açacağı ve dil basacağı takılmadan önce yapıldı. İkinci ölçüm, (TA2) tonsillektomi cerrahisinin sonunda, dil basacağı çıkartıldıktan sonra ancak ekstübasyondan hemen önce yapıldı. Kontrol grubunda, ilk ölçüm (TA1) endotrakeal entübasyondan hemen sonra, ikinci ölçüm (TA2) ise, cerrahi bitiminde ancak ekstübasyondan hemen önce yapıldı. Dil ödemi, dil kesit alanları farkı (TA2 - TA1) olarak tanımlandı. Gruplar dil kesit alanları açısından ve dil ödemi açısından karşılaştırıldı. Bulgular: Gruplar arasında, demografik açıdan ve genel anestezi süreleri açısından fark yoktu. TA1 değerleri bakımından, tonsillektomi (3.93 ± 1.29 cm2) ve kontrol grupları (3.80 ± 1.20 cm2) arasında anlamlı bir fark bulunmadı (p = 0.212). TA2 değerleri bakımından, tonsillektomi grubu (4.63 ± 0.28 cm2) ile kontrol grubu (3.91 ± 0.23 cm2) arasında anlamlı fark bulundu (p = 0.000). Tonsillektomi grubu dil ödemi değerleri (0.90 ± 0.26 cm2), kontrol grubu değerlerine (0.11 ± 0.07 cm2) göre yüksek bulundu (p = 0.000). Sonuç: Çalışmamız ile, erişkin hastalarda gerçekleştirilen tonsillektomi cerrahisinde kullanılan ağız açacağı ve dil basacağının dil üzerinde oluşturduğu yüksek basınca bağlı olarak dil ödemi gelişmiş ve dil ödemi USG ile tespit edilmiştir.
Nadir Gözlenen Ventilasyon Tüpü Komplikasyonu: Tüpün Orta Kulağa Atılması
(Selçuk Üniversitesi, 2020 Haziran) Erdur, Ömer; Çolpan, Bahar; Gül, Osman
Timpanik membrana ventilasyon tüpü tatbiki en sık uygulanan kulak cerrahilerinden bir tanesidir. Kronik seröz otit medianın cerrahi tedavisinde sıkça uygulanan bu yöntem hastada orta kulağın ventilasyonunu sağlayıp orta kulak basıncını düzenler. Ventilasyon tüpü tatbikine bağlı en sık karşılaşılan komplikasyonlar miringoskleroz, atrofi ve otoredir. Tüpün atılım sürecinde mediale doğru yönlenip orta kulağa atılmasıyla sağlam zarın medialinde görülmesi haline oldukça nadir rastlanan bir komplikasyondur. Ventilasyon tüpü tatbiki sonrası komplikasyon çok nadir gözlense de erken dönemde tanınıp tedavi edilmesi durumun daha kötüye gitmesini engelleyecektir.Bu vaka sunumunda rutin takiplerini bırakan geç dönem muayenesinde tüpü orta kulağa atılan ve çevresinde granülasyon dokusu oluşan hastanın literatür eşliğinde sunulması amaçlandı.
The Evaluation of the Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm
(Selçuk Üniversitesi, 2022) Bozdemir, Kazım; Çallıoğlu, Elif Ersoy; Ulusoy, Bülent; Candan, Selami; Koçakoğlu, Nurcan Özyurt; İslamoğlu, Yüce; Serifler, Serkan
Objective: To evaluate the effect of biofilm layer on polyp formation in nasal polyposis by comparing the amount of biofilm layer on polyp tissue and the normal mucosa. Materials and Methods: This study is a prospective study. 14 patients who underwent functional endoscopic sinus surgery (FESS) for nasal polyposis were evaluated. Patients were had no history of previous FESS. Tissue samples were obtained from lower turbinate (Group 1 n:14) and from nasal polyp (Group 2, n:14) of the same nasal cavity. Biofilm presence was identified using scanning electron microscopic (SEM) morphological findings. In biofilm positive samples, the presence of biofilm in less than 25% of the surface area was classified as (+), between 25-50% as (++) , and over 50% as (+++). Results: In Group 2, with SEM imaging, (+++) biofilm presence was detected in 9 patients and (++) biofilm was detected in 5 patients. In Group 1, no biofilm was detected 8 patients, while; (+++), (++), and (+) biofilm presence was detected in 1, 2, and 3 patients respectively. Significant difference was found between group 1 and group 2 with respect to the amount of biofilm according to SEM (p =0.000). Conclusion: In samples, statistically significant difference was found between polyp tissue and normal mucosa in terms of the amount of biofilm. However, further studies with larger patient series are required in order to reach a definitive conclusion on the effect of biofilm on pathogenesis of polyp.
Postconditioning ozone alleviates ischemia-reperfusion injury and enhances flap endurance in rats
(Taylor and Francis Ltd, 2020) Elsürer, Çağdaş; Önal, Merih; Selimoğlu, Nebil; Erdur, Ömer; Yılmaz, Mustafa; Erdoğan, Ender; Kal, Öznur; Çelik, Jale Bengi; Önal, Özkan
Muscle-flap transferring is a routine approach utilized in reconstructive operations; however, flap morbidity is often a source of post-operative difficulty. Ischemia-Reperfusion Injury (IRI) is an important contributor to the viability of flaps after transferring. The goal of this research was for assess the probable useful impacts of ozone on flap survival in a rat muscle-flap design. Materials and Methods: We examined the effects of postconditioning ozone administration on viability of pedicled composite flaps. Twenty-eight Wistar rats were randomized into four groups: sham-operated (S), ischemia-reperfusion (IR), sham-operated + ozone (O), IR + ozone (IR + O), respectively. The animals were sacrificed on the eighth day. In a general histological evaluation, flap tissues were examined with a light microscope, and apoptotic cells were counted. The Apoptotic Index (AI) was then calculated. Flap-tissue samples were sent for analyses of malondialdehyde (MDA), catalase (CAT), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and protein carbonyl (PCO), and blood samples were sent for analyses of Total Oxidant Score (TOS), and Total Antioxidant Capacity (TAC). Data were evaluated statistically using the Kruskal–Wallis test. Results: The histomorphometric score was remarkably greater in O (p =.002). The AI was greater in IR (p =.002). The antioxidant parameters values as regards SOD, GSH-Px, CAT, and TAC were found to be greater in O (p <.005). The oxidant parameters values as regards MDA, PCO, TOS were found to be greater in IR (p <.005). Discussion: The current research indicates that ozone application can attenuate the muscle-flap injury brought about by IR through triggering the increase of the antioxidant capacity.
The relationship between the findings of vestibular evoked myogenic potentials and severity of obstructive sleep apnea syndrome
(SPRINGER, 2020) Ulusoy, Bülent.; Gül, Osman.; Elsürer, Çagdaş.; Bozkurt, Mete Kaan.; Tülek, Baykal.; Körez, Muslu Kazım.; Ekmekçi, Hakan.; Çolpan, Bahar.
Purpose Our study aimed to evaluate the effects of chronic hypoxic state in Obstructive Sleep Apnea Syndrome (OSAS) on brainstem pathways using Vestibular Evoked Myogenic Potential (VEMP) test and to investigate the presence of new markers likely to be correlated with the severity of the disease. Methods The study was planned as prospective and double blind. A total of 60 patients (120 ears) diagnosed with mild, moderate and severe OSAS were included in the study and the patients are grouped as 20 patients in each group. Twenty volunteer healthy individuals (40 ears) shown to be without OSAS were included in the study. VEMP measurements were made in 60 study group patients (120 ears) and in 20 healthy controls (40 ears). The groups were compared in terms of variables such as the acquisition rate of oVEMP and cVEMP waves, interval between the waves, latency and amplitude of the waves. p < 0.05 values were considered as significant. Results The results of cVEMP test showed that the rate of wave acquisition in the moderate and severe OSAS groups was significantly lower than the control group and mild OSAS groups (p = 0.008). There was no difference between the control group and the mild OSAS group in terms of the rate of obtaining the wave (p > 0.05). In the moderate and severe OSAS groups, P1N1 amplitude and N1P2 amplitude values were found to be significantly lower than the mild OSAS group (p = 0.007 and p = 0.017, respectively). In the oVEMP test, there was no significant difference between the mild OSAS group and the control group in terms of the wave yield (p > 0.05); however, it was found that the rate of wave acquisition in the moderate and severe OSAS groups was significantly lower than the mild OSAS group (p = 0.041). There was inverse correlation between the N1P2 interval and P1N1 amplitude value and AHI in simple regression analysis and multiple regression analysis (p = 0.012 and p = 0.021; p = 0.009 and p = 0.040, respectively). Conclusion The negative effects of chronic intermittent hypoxia related with OSAS on the brainstem and vestibular system can be demonstrated by VEMP tests. Especially, the inability to obtain the wave is the most important finding showing this situation. Also, we think that N1P2 interval and P1N1 amplitude markers can be used to detect the subclinical negative effect of chronic hypoxia on vestibular nuclei in the brainstem.
The role of regulatory T cells in allergic rhinitis and their correlation with IL-10, IL-17 and neopterin levels in serum and nasal lavage fluid
(SPRINGER, 2020) Erkan, Kadriye.; Bozkurt, Mete K.; Artaç, Hasibe.; Özdemir, Hülya.; Ünlü, Ali.; Korucu, Emine N.; Elsürer, Çağdaş.
Purpose Allergic rhinitis (AR), is an IgE-mediated inflammation of the nose. Regulatory T cells (Tregs) and inflammatory cytokines have been shown to play a critical role in allergic airway inflammation. The aim of the study was to compare the levels of blood T lymphocyte subsets and IL-10, IL-17 and neopterin concentrations in serum and nasal lavage of patients with AR compared to healthy subjects. Methods The study included 38 subjects with moderate-severe AR and 36 sex- and age-matched controls. Peripheral blood CD3+, CD3+CD4+ and CD4+CD25+Foxp3 percentages were evaluated using flow cytometry. Levels of IL-10, IL-17 and neopterin were measured both in serum and nasal lavage fluid with ELISA and HPLC, respectively. Results No difference was found in the percentages of T lymphocyte subsets between the two groups (p > 0.05). Serum IL-10 levels were similar (p > 0.05), whereas nasal IL-10 was lower in AR subjects compared to control group (2.22 +/- 0.91 and 3.12 +/- 1.45 pg/ml, respectively) (p < 0.05). Mean serum and nasal IL-17 were higher in AR (107.7 +/- 79.61 and 527.36 +/- 738.7 pg/ml) than the control group (76.29 +/- 28.94 and 328.9 +/- 430.8 pg/ml) (p < 0.05 and p > 0.05). There were no significant differences in serum and nasal neopterin levels (p > 0.05). Conclusions Although there were no differences in the distribution of lymphocyte subsets between the AR and control groups, the finding of higher levels of serum and nasal IL-17 and lower levels of nasal IL-10 support the cytokine imbalance in the pathogenesis of AR.
Sleep habits and related factors in kindergarten children
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019) Durduran, Y.; Pekcan, S.; Çolpan, B.
Aim: This study aimed to determine the sleeping habits and sleeping periods of kindergarten children, in order to analyze the problems related to sleep hygiene and determine the underlying factors. Methods: The sample size of this cross-sectional study consisted of 390 children. A questionnaire filled in by the parents was used as the data collection tool. The data were analyzed with appropriate statistical tests. Results: According to the mothers, 77.2% of the children had their own room at home. Thirty nine percent of children slept with the full light on in their room, 50.3% slept with night light on in their room, 12.3% slept with the radio/television on in their room. Infant sleep practices found in this study are swaddling (18.5%), wrapping of the infant's arms (21.0%), and rocking (58.7%). Conclusions: In terms of sleep hygiene, the vast majority of the children slept in a bright environment, and there were electronic appliances in the room. Common infant-transition-to-sleep practices observed were wrapping their arms and swaddling them. In our point of view, awareness training for parents about the subject will support sleep hygiene practices.
Long-term follow-up of tonsillectomy efficacy in children with PFAPA syndrome
(ASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIAL, 2019) Aktaş, Öztürk; Aytuluk, Hande Gürbüz; Çalışkan, Sebla Kumaş; Erdur, Ömer; Cırık, Ahmet Adnan
Introduction: The role of tonsillectomy in the periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome, is controversial. Although some studies reported high success rates with tonsillectomy, further investigations are needed with larger numbers of patients. Objective: To seek the long-term outcomes of tonsillectomy in periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome. Methods: Case series; multi-center study. The study comprised 23 patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome who underwent surgery (tonsillectomy with or without adenoidectomy) between January 2009 and November 2014. Results: 21 (91%) of 23 patients had complete resolution immediately after surgery. One patient had an attack 24 h after surgery, but has had no further attacks. One patient had three attacks with various intervals, and complete remission was observed after 3 months. Conclusions: Tonsillectomy is a good option for the treatment of periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome. (C) 2017 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda.
Evaluation of upper oesophageal sphincter in unilateral vocal fold paralysis
(CAMBRIDGE UNIV PRESS, 2019) Erdur, O.; Gul, O.; Ozturk, K.
Objective To evaluate dysphagia and manometric changes in the upper oesophageal sphincter in patients with unilateral vocal fold paralysis. Methods Thirty patients with unilateral vocal fold paralysis due to vagal nerve paralysis scheduled for evaluation were enrolled in the study group; 24 healthy subjects were included in the control group. Upper oesophageal sphincter basal and residual pressure, relaxation time, and pharyngeal pressure values were evaluated by manometry. All patients completed the Turkish Eating Assessment Tool 10 questionnaire, the MD Anderson dysphagia questionnaire and the reflux symptom index form. Results Swallowing assessment questionnaires and reflux symptom index results were significantly higher in the study group. Upper oesophageal sphincter basal and relaxation pressures were lower in the study group. Upper oesophageal sphincter relaxation time was shorter in the study group, but pressure values recorded from the pharynx were higher. Conclusion Upper oesophageal sphincter manometric pressure was lower in patients with unilateral vocal fold paralysis. A hypotonic sphincter likely contributes to dysphagia and aspiration.
Evaluation of the facial soft-tissue thickness in patients with cleft lip and palate
(LIPPINCOTT WILLIAMS & WILKINS, 2019) Erdur, Emire Aybuke.; Baka, Zeliha Muge.; Fidanboy, Merve.; Erdur, Omer.
Aim: In this study the authors aimed to evaluate craniofacial morphology and facial soft tissue thickness of the patients with cleft lip and palate.(CLP), and to compare the results with a sex and age-matched noncleft healthy control group. Methods: Craniofacial and soft tissue thickness measurements of 20 patients with unilateral cleft lip palate (UCLP) and 20 patients with bilateral cleft lip palate (BCLP) were compared with 20 noncleft control subjects. Angles between Sella-Nasion-A point, Sella-Nasion-B point, Nasion-A and Nasion-B line, Sella-Nasion line and Gonion-Gnation line, and linear (glabella, rhinion, subnasale, labrale superius, stomion, labrale inferius, labiomentale, pogonion, and gnathion) measurements were assessed on lateral cephalometric radiographs. Group differences were evaluated with 1-way analysis of variance and post hoc Tukey test. Results: Unilateral cleft lip palate and BCLP groups demonstrated lower values of skeletal measurements than control group except for Sella-Nasion line and Gonion-Gnation line value (P< 0.01). Maxillary incisors were retruded in BCLP group compared with the other groups (P< 0.001). Thickness of the rhinion, subnasale, and stomion demonstrated no significant difference between UCLP and BCLP groups (P> 0.05). Thickness of rhinion and stomion was found significantly higher in both groups, and thickness of the subnasale was found significantly lower than the healthy group (P< 0.05). Conclusion: Findings of the study suggested that patients with CLP showed differences on craniofacial morphology and facial soft tissue thickness. Before planning orthodontic treatment and esthetic surgeries, soft tissue thickness should be taken into consideration in addition to skeletal measurements in CLP patients.
The relation between idiopathic subjective tinnitus and risk factors for venous and arterial thrombosis
(2019) Ulusoy, Bülent
Aim: The aim of this study was to investigate the relationship between tinnitus and the factors that cause the tendency to thrombosisin terms of gender.Material and Methods: Fifty-five consecutive patients who admitted to our clinic with the complaint of idiopathic subjective tinnituswere included in this study. Routine ENT (ear nose throat) examinations and pure tone audiometry test were performed. Prothrombintime (PT), partial thromboplastin time (PTT), total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein(HDL) cholesterol, Triglycerides, antithrombin III (AT III), protein C, protein S, homocysteine, antiphospholipid and anticardiolipinantibodies were examined in blood samples of patients. Temporal bone magnetic resonance imaging (MRI) was performed allpatients. The results of the patients were compared in terms of gender and age groups (40 and 40 age).Results: The study was completed with 47 patients. Twenty-four of the patients were female and 23 were male. Both genders groupswere similar in terms of age and pure tone average. Antiphospholipid and anticardiyolipin antibodies (IgG and IgM) were found asnegative in all patients. Homocysteine levels were found to be statistically significantly higher in males than females (p0.015;respectively 13.385.98 ?mol/L and 9.873.11 ?mol/L). AT III and Protein S levels were lower in males than females although thisdifference was not statistically significant (respectively p0.07 and p0.08)Conclusion: In this study, an association was shown between hyperhomocysteinemia and tinnitus, especially in males.
Effects of Endoscopic Endonasal Sinus Surgery on Nasal flora in Patients with Chronic Rhinosinusitis with Nasal Polyps
(2019) Ulusoy, Bülent; Müderris, Tuba; Çallıoğlu, Elif Ersoy; Bozdemir, Kazım; Oğuzhan, Tolga; Kutluhan, Ahmet; Açıkgöz, Ziya Cibali
Aim: This study aimed to evaluate the alterations in the nasal flora in patients who underwent endoscopic endonasal surgery forchronic rhinosinusitis with nasal polyps (CRSwNP).Material and Methods: This prospective study included 30 patients diagnosed with CRSwNP who were resistant to medicaltreatment and recommended for surgery. The nasal cavity was sampled two times, first preoperatively on the day of operation andpostoperatively in the 4th week. Patients were divided into two groups according to their culture results, including normal florabacteria and potential pathogen production.Results: In the preoperative swab samples, 3 (11.1%) patients had no bacterial growth, 16 (59.3%) patients had a normal flora, andpotential pathogens were detected in 8 (29.6%) patients. However, postoperatively, 3 (11.1%) patients had no bacterial growth, 13(48.1%) patients had a normal flora, and potential pathogens were detected in 11 (40.7%) patients during the postoperative period.No significant difference was found between preoperative and postoperative culture results in terms of the number of patientswith normal flora, potential pathogens, and no bacterial growth (p0.676). The most common microorganism in the normal floragroup preoperative and postoperative period was coagulase-negative Staphylococcus (77.8%, 51.9%, respectively), and the mostcommon microorganism in the potential pathogen group was Staphylococcus aureus (18.5% and 25.9%, respectively). Comparingpreoperative and postoperative culture results according to isolated potential pathogen microorganism types, no statisticallysignificant difference was observed for any microorganism in the potential pathogen group (p0.05).Conclusion: As a result, no correlation between nasal polyps’ surgery and potential pathogens was detected.
Ear laterality in sudden sensorineural hearing loss
(2019) Ata, Nurdogan; Tezer, Mesut Sabri; Erdur, Ömer; Bülbül, Tahir; Demirkan, Abdullah; Gogus, Halil Emre; Karaoğlu, Emre; Ciftci, Mehmet Ali
Aim: Sudden sensorineural hearing loss (SSHL) is usually diagnosed in a single ear. The main objective of this study is to assess thedominance of affected ear by comparing right versus left-ear cases.Materials and Methods: We retrospectively examined the records of 105 patients (63 males, 42 females; mean age 41.515 years;range 18 to 72 years) between January 2013 and January 2017.Results: Sixty-three of the included cases were male and 42 were female patients. SSHL was diagnosed on the left ear in 51 (48.6%)patients and on the right ear in 49 (45.7%) patients. No statistically significant dominance on the affected ear side was detectedwhereas bilateral involvement was significantly low. In male patients, 33 (52.3%) had hearing loss on the right and 29 (46%) hadhearing loss in the left ear. Sixteen (32.7%) female patients had right ear and 22 (43.1%) had left ear involvement. There was a slightdominance on the right ear in male and on the left ear in female patientsConclusion: There is no significant difference between left and right ear involvement in SSHL. The results of our study which showedright ear dominance in males and left ear dominance in female patients are thought to be purely coincidental.
Intratympanic steroid injection and hyperbaric oxygen therapy for the treatment of refractory sudden hearing loss
(ASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIAL, 2018) Gülüstan, Filiz; Yazıcı, Zahide Mine; Alakhras, Wesam M. E.; Erdur, Ömer; Acıpayam, Harun; Küfeciler, Levent; Kayhan, Fatma Tulin
Introduction: Controversy surrounds the use of salvage therapies to treat sudden sensorineurat hearing loss (SSNHL), with no consensus on recommendations. White several studies have demonstrated the effectiveness of intratympanic administration of steroids (ITS) and hyperbaric oxygen (HBO) treatment, few have compared the efficacy of ITS and HBO therapy in patients with refractory SSNHL. Objective: We evaluated the efficiency of ITS and HBO therapy in patients with refractory SSNHL. Methods: Patients who did not adequately benefit from systemic treatment were evaluated retrospectively. Refractory patients were defined as those who gained less than 20 dB in hearing after initial treatment. All refractory patients were informed about salvage therapy options: ITS or HBO therapy, the advantages and disadvantages of which were explained briefly. ITS involved 4 mg/mL dexamethasone administered through a 25 gauge needle. Patients underwent HBO therapy in a hyperbaric chamber where they breathed 100% oxygen for 120 min at 2.5 atmospheric pressure. The hearing levels of both groups were evaluated before the salvage therapy and at 3 months after treatment. Improvements in hearing were evaluated according to the Furahashi criteria. We also compared the two therapies in terms of speech discrimination scores (SDSs) and the recovery of all frequencies. Results: The salvage therapies generated similar results. Changes in pure tone averages and SDSs were similar for ITS and HBO therapy (p = 0.364 and p = 0.113). Comparison of SDSs and hearing thresholds at all frequencies showed similar levels of improvement. Conclusion: ITS and HBO therapy produced similar improvements in SSNHL patients, but the sample size was too small to draw definitive conclusions. Further randomized controlled studies are needed to identify the best therapy for patients with refractory sudden hearing loss. (C) 2016 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda.
Feasibility of a septal mucosal flap for preventing re-stenosis following the draf III procedure
(CAMBRIDGE UNIV PRESS, 2018) Erdur, O.; Ozturk, K.; Erkan, K.
Background: Re-stenosis and a consequent need for revision surgery are the most common problems in the follow-up period following endoscopic modification of the Lothrop procedure. Method: This paper reports a new technique for reconstructing and resurfacing of the posterior frontal recess bone for prevention of re-stenosis. Results: A 46-year-old man presented with a frontal sinus osteoma, and treatment featured an endoscopic modification of the Lothrop procedure. A vascularised, posteriorly based, septal mucosal flap was used in reconstruction. There have been no reported issues over 24 months of follow up. Conclusion: The use of a nasoseptal flap seems feasible to reduce scarring and recurrence of (common) frontal recess stenosis after a Draf III operation.
Temporal kemik fraktürü sonrası geç dönem fasiyal sinir dekompresyon cerrahisi sonuçlarımız
(2018) Eryılmaz, Mehmet Akif; Aydemir, Fuat; Arbağ, Hamdi; Arıcıgil, Mitat
Amaç: Bu çalışmanın amacı temporal kemik travması sonrasında gelişen fasiyal sinir paralizi olgularının klinik özelliklerini ve geçdönem fasiyal sinir dekompresyon sonuçlarımızı sunmaktır.Gereç ve Yöntem: Ocak 2010 - Mart 2016 tarihleri arasında, temporal kemik travması sonucu fasiyal sinir paralizisi oluşan ve geçdönem fasiyal sinir dekompresyonu uygulanan on hastanın dosyaları retrospektif olarak tarandı. Yaş, cinsiyet, travma etiyolojisi, otoskopikbulgular, işitme kaybı, radyolojik görüntüleme ve takip sonuçları açısından hasta dosyaları incelendi.Bulgular: Çalışmaya katılan hastaların tamamı erkekti ve yaş ortalaması 28,3 idi. Tüm olgulara transmastoid yaklaşım ile fasiyal sinirdekompresyonu uygulandı. Cerrahi sırasında beş hastada fasiyal sinir etrafında ödem, dört hastada kemik spikülleri basısı ve bir hastadagranülasyon dokusu izlendi. Fasiyal sinir paralizi başlangıcından itibaren dört haftadan kısa sürede opere olan üç olguda normal veyanormale yakın (House Brackmann evre 1-2) düzelme görülürken, sekiz haftadan uzun sürede opere olan iki olguda kısmi düzelmegörülmüştür.Sonuç: Sonuç olarak temporal kemik fraktürü sonrasında oluşan fasiyal sinir paralizisi olgularında cerrahi endikasyon durumlarındamümkün olduğu kadar erken dönemde dekompresyon uygulanmalıdır. Fakat bizim çalışmamızda geç dönem fasiyal sinir dekompresyoncerrahisi uygulanan olgularda da başarılı sonuçlar alınabileceği ve tam veya tama yakın iyileşme olabileceği görülmüştür.
Effect of septoplasty on the mean platelet volume and inflammation markers
(2018) Ulusoy, Bülent; Bozdemir, Kazım; Mişe, Halil İbrahim; Kutluhan, Ahmet; Korkmaz, Mehmet Hakan
Objective: Nasal septal deviation is an obstructive pathology and can be related to inflammation. This study aimed to investigate therelationship between nasal septum deviation leading to obvious nasal obstruction and certain variables including mean platelet volume(MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR). The study will alsoexamine the effect of this operation on this relationship.Materials and Methods: This is a prospective study. The study sample included 29 patient group participants that had septoplastyindications, and 31 control group participants that were healthy volunteers. Control and patient groups were compared with regard to MPV,PDW, NLR, PLR, platelet count and white blood cell (WBC) counts. The significance level was accepted as 0.05 in the relevant statisticalanalyses.Findings: The preoperative MPV and PDW levels were found to be higher in the patient group than the control group. The differencebetween them was statistically significant (p 0.05). In the patient group, the researchers observed a decrease of 0.72 units in the MPV valueand 0.91 units in the PDW value, and an increase of 6.72 units in the platelet count at the end of the month following the operation comparedwith the relevant values in the preoperative period (p 0.05).Result: The MPV and PDW values were high in the patients with nasal septum deviation requiring surgery. Moreover, these high MPVand PDW values were found to normalize after the operation.
Use of magill forceps to remove foreign bodies in children
(THIEME MEDICAL PUBL INC, 2017) Oncel, Murat.; Sunam, Guven Sadi.; Elsurer, Cagdas.; Yildiran, Huseyin.
Introduction Esophageal foreign body (FB) in all age groups can cause serious morbidity or mortality. The study aims to report our experience retrieving FBs from the upper esophagus in children using Magill forceps. Materials and Methods In this study, 88 patients (45 males [51.1%] and 43 females [48.9%]) were presented with suspected FB ingestion. FB ingestion was determined via endoscopic analysis, or lateral and posterior-anterior radiographies, including oropharynx, neck, chest, and abdomen. Cases were classified into seven groups, according to history, diagnostic method, and postintervention findings, as follows: (1) coins, (2) toys, (3) metals, (4) bones, (5) battery, (6) glass, and (7) food. A laryngoscope was used to elevate the larynx and expose the esophageal entrance. Magill forceps were advanced into the esophagus and opened to observe and extract the FB. Results All 88 patients who underwent endoscopic examination due to suspected FB ingestion were confirmed to have ingested a FB. Median age was 12 years; 15 patients were aged < 5 years; 63 (71.5%) were diagnosed based on routine radiographic findings, and others were diagnosed based on physical findings and history. The most common type of FB was coins (n = 51 [57.9%]). Mean surgical duration was 20 minutes. Conclusion FBs located at cervical esophageal level are usually the most difficult to remove. Magill forceps should be used before other methods.
Ses eğitimi alan kadınların menstrual döngü - menstrual, folliküler ve premenstrual evre-ses özellikleri
(2017) Doğanyiğit, Satı; Yiğit, Nalan; Öztürk, Kayhan
Ses eğitimi alan kadınların menstrual döngünün menstrual, folliküler ve premenstrual evrelerine ait ses özelliklerinin araştırılması amacıyla yapılan bu çalışma, durum tespitine yönelik tarama modelindedir. Çalışma grubu Necmettin Erbakan Üniversitesi Müzik Eğitimi Anabilim Dalında öğrenim gören 15 kız öğrenciden oluşmaktadır. Sesin, görsel özellikleri VLS (Videolarengostroboskopi), akustik özellikleri CSL (Computerized Speech Laboratory) 4500 bilgisayar ortamında Kay Elemetrics MDVP (Multi Dimensional Voice Program) ve Shure Sm 48 model mikrofon, VRP (Voice Range Profile) ile aerodinamik özellikleri PAS (Phonatory Aerodynamics System) ile belirlenmiş olup verilerin analizinde istatistikî yöntemlerden tekrarlı ölçümler ve friedman testleri kullanılmıştır. Ses özelliklerinden elde edilen veriler menstrual döngünün menstrual, folliküler ve premenstrual evreleri arasındaki farklılık açısından değerlendirilmiş; comfortable sustained phonation parametresi mean picth, voicing efficiency parametresi mean picth, VRP protokollerinden minimum F0 (Hz) VRP Fizyolojik ve F0 @ Max, Energy (Hz) VRP Fizyolojik açılarından anlamlı bir fark olduğu görülmüştür. Premenstrual evrede en sık bildirilen şikâyet ses yorgunluğu ve ses kısıklığı olmuştur.
Management of pleomorphic adenoma in the nasopharynx: A case report
(GALENOS YAYINCILIK, 2015) Yazıcı, Zahide Mine; Yeğin, Yakup; Erdur, Ömer; Çelik, Mustafa; Kayhan, Fatma Tülin
Background: Pleomorphic adenomas (PAs) are the most common type of benign salivary gland tumours and usually originate from the major salivary glands. PA originating from the nasopharynx has rarely been reported in the literature. Case Report: A 62 year-old male presented with right aural fullness and subjective hearing loss. Otoscopic examination revealed an opaque and bulging tympanic membrane. Nasal endoscopic examination revealed a smooth mass arising from the right wall of the nasopharynx, obstructing the opening of the right Eustachian tube. The MRI showed a 1.3x2x1.3 cm sharply outlined and lobar mass in the right lateral wall of the nasopharynx. The tumour was meticulously detached from its attachment site and excised via the transnasal route under endoscopic visualisation. Conclusion: We reported pleomorphic adenoma in the nasopharynx in a patient who presented with serous otitis media that successfully resected with transnasal endoscopic surgery and discussed the treatment methods.

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