Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları/Makale Koleksiyonu
Bu koleksiyon için kalıcı URI
Güncel Gönderiler
Öğe The relationship between chronotype and obesity in children and adolescent with attention deficit hyperactivity disorder(TAYLOR & FRANCIS INC, 2019) Türkoglu, Serhat; Çetin, Fatih HilmiChildren and adolescents with Attention De?cit Hyperactivity Disorder (ADHD) have a high prevalence of obesity, but the relationship between these two problems is not clear. Chronotype preferences may be one of the possible mechanisms underlying the link between ADHD and obesity. This is the ?rst study to investigate whether chronotype preferences are a mechanism linking ADHD symptoms to obesity in children and adolescents. This cross-sectional study included 110 drug-naive children and adolescents aged 7-17 years with ADHD. The Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL) was used to diagnose ADHD or to exclude psychiatric comorbidity. The Conners' Parents Rating Scale-Revised Short Version (CPRS-RS) and Children's Chronotype Questionnaire (CCQ) were used to assess the severity of ADHD symptoms and chronotype preferences. Body mass index (BMI) was calculated and classified according to national age- and gender-specific reference values. The participants were divided into three groups as normal weight (<85%, n = 38), overweight (85%-95%, n = 30) and obesity (>95%, n = 42) according to their BMI percentile. There were statistically significant differences between the three groups in terms of chronotype preference (p = .000). Morningness preference was 86.84% in the normal BMI group and 26.19% in the obese BMI group. Eveningness preference was 7.89% in the normal BMI group and 61.90% in the obese BMI group. There was a correlation between the BMI percentile scores and the morningness/eveningness scale (M/E) scores. Moreover, there was a correlation between the BMI percentile scores and the oppositional and ADHD index scores. According to logistic regression analysis, the odds ratio of having evening type for obesity was 5.66 and the odds ratio of having morning type for normal weight was 13.03. Independently from ADHD symptoms, eveningness was directly related to obesity and morningness was directly related to normal weight. Prospective studies should be performed to better understand the relationship between ADHD, overweight/obesity and chronotype.Öğe Psychological well-being among ınternally displaced adolescents and the effect of psychopathology on ptsd scores depends on gender(SPRINGER, 2019) Eray, Safak; Murat, Duygu; Ucar, Halit Necmi; Gonullu, EdipThe purpose of this cross-sectional study was to investigate the post-traumatic symptoms and psychological well-being among internally displaced (ID) adolescents in the early phase of the conflict in the southeast part of Turkey and clarify the effect of psychopathology on PTSD scores depends on gender. With the help of the results of our study, we aimed to enhance our understanding of adolescent mental health. Our study was completed with 102 ID adolescents (42 boys, 60 girls). Our results showed that ID adolescents flee from conflict had significantly higher levels of mental disorders and PTSD. Girls show higher rates of PTSD symptoms than boys and there was no significant interactive effect of gender and emotional, behavioral and peer problems on PTSD. However, boys with ADHD seem to be more prone to develop PTSD than girls. We aimed to highlight the challenges facing adolescents forced to flee from conflict zones who were temporarily relocated. These results may help us to enlighten our understanding of ID adolescents and may suggest more studies to provide beneficial gender-specific intervention program.Öğe Processing speed may improve earlier than response inhibition/ interferens in children with ADHD-combined type receiving methylphenidate: a single-center study(TAYLOR & FRANCIS LTD, 2019) Çetin, Fatih Hilmi.; Güler, Hasan Ali.; Ersoy, Sevde Afife.; Türkoğlu, Serhat.OBJECTIVES: The aim of this study was to determine the order of improvement in response inhibition, interference capacity, and processing speed in the Stroop test after starting methylphenidate treatment in children with ADHD. METHODS: This study included a total of 52 children aged 7-16 years who were diagnosed with combined-type ADHD for the first time and who began to use methylphenidate treatment. The Stroop test was applied to each subject at least 3 times (before treatment and at the first and second months of treatment) in the follow-up visits. RESULTS: The participants completed the fifth section of the Stroop test at a median duration of42.09 sec (quartiles: 35.58-54.0 sec) before treatment, while the median duration was 34.49 sec (quartiles: 27.43-34.48 sec) at the first month of treatment and 32.18 sec (quartiles: 26.97-32.18 sec) at the second month of treatment. The task completion duration showed a statistically significant improvement from the first month of treatment (p < 0.001). When the participants were compared in terms of the number of errors and corrections they made in the fifth section of the Stroop test, there was no significant difference between pretreatment measurements and post-treatment first month measurements (p > 0.05). The number of errors and corrections were statistically significantly lower in the second month of treatment compared to pretreatment and 1st mont of the treatment (p < 0.05). CONCLUSIONS: This study demonstrated that processing speed, response inhibition, and interference capacity assessed by the Stroop test improved with methylphenidate treatment in children with ADHD. This study is the first study to show that these improvements occur in a certain order over time.Öğe Parent-reported social problems and clinician-evaluated adverse effects may be differentially affected by differing extended release methylphenidate formulations: a prospective, naturalistic study from Turkey(TAYLOR & FRANCIS LTD, 2019) Uytun, Merve Cikili.; Cetin, Fatih Hilmi.; Babadagi, Zehra.OBJECTIVE: Medikinet retard (R) is a nonosmotic, extended-release formulation of Methylphenidate (MPH) and has been used in Turkey for the last 4-5 years. The aim of our study is to compare the efficacy on functionality of Medikinet retard (R) and Concerta (R) and their adverse events. METHODS: Participants were referred to the Kayseri Training and Research Hospital and followed up there between August 2016 and June 2018. This study design is a 16-week prospective trial, each child received 16 weeks of OROS-MPH or MPH-ER. A total of 103 children were enrolled in the study, but only 70 children (n = 35 concerta, n = 35 medikinet retard) completed the study. Weiss Functional Impairment Rating Scale-Parent Report Form (WFIRS-P) and Barkley Side Effect Rating Scale (BSERS) were used for assessment. RESULTS: In both treatment groups, children improved significantly over time, both in intensity and in the number of problems. Regarding the social problems, Medikinet retard (R) was superior to the Concerta in terms of effects. The side effects of insomnia and euphoria were seen more common in the Concerta (R) group than the Medikinet retard (R). Additionally, the mean severity scores of euphoria were shown higher in the Concerta (R) group than the Medikinet retard. CONCLUSION: From this study, we concluded that Medikinet retard (R) is also an effective and safety MPH formulation.Öğe Effect of adenotonsillectomy on sleep problems, attention deficit hyperactivity disorder symptoms, and quality of life of children with adenotonsillar hypertrophy and sleep-disordered breathing(SAGE PUBLICATIONS INC, 2019) Türkoğlu, Serhat.; Somuk, Battal Tahsin.; Sapmaz, Emrah.; Bilgiç, Ayhan.Objective Chronic adenotonsillar hypertrophy is the most common etiologic reason for upper airway obstruction in childhood and has been found to be associated with a variety of psychiatric disorders and poor quality of life. In the present study, we investigated the impact of adenotonsillectomy on attention deficit hyperactivity disorder symptoms, sleep problems, and quality of life in children with chronic adenotonsillar hypertrophy. Methods The parents of children with chronic adenotonsillar hypertrophy filled out the Conners's Parent Rating Scale-Revised Short form (CPRS-RS), Children's Sleep Habits Questionnaire (CSHQ), and Pediatric Quality of Life Inventory, Parent version (PedsQL-P) before and six months after adenotonsillectomy. Results A total of 64 children were included in the study (mean age = 6.8 +/- 2.4 years; boy:girl ratio= 1). The mean attention deficit hyperactivity disorder index and oppositionality subdomain scores of the CPRS-RS and all of the CSHQ subdomain scores (bedtime resistance, sleep-onset delay, sleep anxiety, night waking, parasomnias, sleep-disordered breathing, and daytime sleepiness) except for sleep duration significantly decreased after adenotonsillectomy (p < 0.05). The PedsQL-P total score and both PedsQL-P physical health and psychosocial health subdomain scores were significantly higher at six months after adenotonsillectomy (p < 0.001). Conclusions Child and adolescent psychiatrists should check the symptoms of chronic adenotonsillar hypertrophy to identify children with chronic adenotonsillar hypertrophy who suffer from sleep disturbance, attention deficit hyperactivity disorder symptoms, and oppositionality. Adenotonsillectomy seems to be beneficial for coexisting attention deficit hyperactivity disorder and sleep disorder symptoms and quality of life in these children.Öğe Digital rectal stimulation associated with psychiatric disorders as a rare reason of solitary rectal ulcer in children and adolescents: a case series(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2019) Cetin, Fatih Hilmi.; Emiroglu, Halil Haldun.; Turkoglu, Serhat.Solitary rectal ulcer syndrome is one of the rare causes of rectal bleeding in children and adolescents. Traumatic and ischemic mucosal injury is the main cause of its etiopathogenesis. A rare but important cause of traumatic mucosal injury is digital rectal stimulation. It is known that digital rectal stimulation is used in order to increase intestinal motility and to reduce the feeling of inadequate defecation. In this study, it was emphasized that digital rectal stimulation can be seen as a consequence of psychiatric disorders, and with proper psychiatric interventions, digital stimulation behavior and solitary rectal ulcer syndrome can be improved. Moreover, the importance of a cooperation between gastroenterologist and psychiatrist in such cases has been stressed.Öğe Dikkat eksikliği ve hiperaktivite bozukluğu olan ergenlerde bağlanma özellikleri ve ebeveyn tutumları(GALENOS YAYINCILIK, 2019) Uzun, Mehmet Erdem.; Uçar, Halit Necmi.; Vural, Ayşe Pınar.INTRODUCTION: Children and adolescents with attention deficit hyperactivity disorder (ADHD) experience problems with adults, especially with their parents, due to self-regulation deficiencies involving impulse control, self-restraint and inhibition problems. It is also reported that problems in parental attitudes play an important role in increasing the severity of ADHD findings. Because of these two conditions, we thought that there may be a relationship between attachment patterns and parenting styles of adolescents with ADHD. METHODS: 59 adolescents with ADHD and 66 adolescents without any psychopathology were included in the study. Socio-demographic data form and Adolescent Relationship Scales Questionnaire were applied to participants and Parental Attitude Research Instrument was applied to their parents. RESULTS: There was no statistically significant difference in attachment styles between ADHD and control group. Parents of the ADHD group had significantly higher scores in the subscales of rejection of the homemaking role, marital conflict, and strict discipline than parents of the control group. Higher levels of dismissing attachment style were associated with higher strict discipline attitudes in the ADHD group. DISCUSSION and CONCLUSION: Our study suggests that evaluation of attachment characteristics and parental attitudes in ADHD that is a neurodevelopmental disorder, may be necessary as an integrated approach.Öğe Attention deficit hyperactivity disorder and anti-Purkinje autoantibodies: no link?(TAYLOR & FRANCIS LTD, 2019) Çetin, Fatih Hilmi; Çetin, Feyza; Işık, Yasemen; Güney, Esra; Alp, Feyza; Aksoy, AltanOBJECTIVES: Attention Deficit Hyperactivity Disorder (ADHD) is a neurobehavioral disorder that begins in early childhood, and many factors play role in its etiology. Many studies have been conducted to identify the causes of ADHD, but the exact factors are still unknown. Although cerebellar dysfunction in the etiology of ADHD was shown in different studies, the possible causes of dysfunction and the role of neuroinflammation among these causes has not been clarified yet. Anti-Yo is an antibody against the antigens in the cytoplasm of purkinje cells and indicates cerebellar degeneration, and Anti-Hu and Anti-Ri are antibodies against cellular nuclear antigens of purkinje cells. This study aimed to evaluate the role of neuroinflammation that is a potential cause of cerebellar dysfunction, which is thought to be an important factor in the development of ADHD. METHODS: This is a cross-sectional and descriptive study that aimed to evaluate the potential association between ADHD and cerebellar neuroinflammation by comparing the serum anti-purkinje cell antibody measurements between case and control groups. The cases were recruited at the Gazi University Child Psychiatry Department, and laboratory analyses were performed at the Ankara Numune Research and Training Hospital Medical Microbiology Department. Sixty children and adolescents with ADHD, and 60 healthy controls were planned to be included in the study. Cases that admitted with ADHD symptoms were given Conners teacher forms according to routine procedure; then the cases with scores over the cut-off of Conners teacher form were evaluated clinically for a diagnosis of ADHD, and after clinical evaluations they were asked to participate the study if they met the eligibility criteria. If they accept to participate the study, informed consents were given to cases and parents, and meanwhile, Turkish version of Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL) was also applied to cases. A 5-ml serum was spared from the blood samples that obtained for routine test during diagnosis. Control group was planned to be formed from the blood samples of 60 healthy children that admitted to child psychiatry clinic for counselling. At the time of analyses, diluted according to the directions of manufacturers, incubated with fluorescent staining including antibodies (Anti-Hu, Anti-Yo, and Anti-Ri), and evaluated under immunofluorescent microscope by three specialists. RESULTS: Sixty healthy volunteers and 60 cases with ADHD were included in the study. Some of the samples were excluded from the study due to the damage to laboratory tubes during transport. Assessments were conducted with 52 ADHD and 52 healthy control samples. The male/female ratio was 41/11(78.8%/21.2%) in the patient group and 35/17 (67.3%/32.7%) in the control group (p = 0.185). Average age was 9.812.41 in the patient group and 9.46 +/- 2.14 in the control group (p = 0.442). No positive results were obtained for anti-Purkinje antibody in ADHD or control groups. CONCLUSIONS: No evidence regarding the potential role of cerebellar neuroinflammation in the etiology of ADHD was determined in this study. But these results need replication in larger samples and different methods.
