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Öğe Detection of colonic masses with MR colonography(2006) Haykir R.; Karaköse S.; Karabacako?lu A.; Kayaçetin E.; Şahin M.Background/aims: Magnetic resonance colonography based on magnetic resonance imaging is a relatively new diagnostic modality for diagnosing colon pathology. The aim of this study was to evaluate its performance in detecting colorectal masses. Methods: Thirty-three patients (20 male, 13 female; age range 28-85 years; mean age 78.7) suspected of having colonic lesions because of rectal bleeding, positive fecal occult blood test results or altered bowel habits underwent magnetic resonance colonography and subsequent conventional colonoscopy. All patients underwent standard bowel preparation 24 h before magnetic resonance colonography. Patients were placed in a supine position on the magnetic resonance table. After placement of a rectal tube, the colon was filled with of a mixture of 1000-1800 ml 0.9% NaCl solution and 15-20 ml 0.5 mmol/L gadopentetate dimeglumine solution. Once colonic distension was achieved, 3D GRE magnetic resonance colonography and complementary Magnetic resonance images were taken in all cases. Results: Sensitivity of magnetic resonance colonography for colorectal masses was 90% and specificity was 100%. Percentage of correct diagnosis of magnetic resonance colonography was 94.3%. Magnetic resonance colonography was well tolerated without sedation or analgesia. Conclusions: Magnetic resonance colonography is a new technique for imaging of the colon. Magnetic resonance colonography has potential advantages of multiplanar capabilities and of being a less-invasive imaging technique; it can be implemented in daily practice and has a role in accurately staging colorectal cancers. In symptomatic patients, this new technique shows promising results for the detection and imaging of colorectal masses.Öğe Evaluation of phagocytic function of the spleen after splenic artery ligation in secondary hypersplenism(2003) Vatansev C.; Tekin S.; Şahin M.; Serdengeçti M.; Avunduk M.C.The aim of this study was to investigate the effects of splenic artery ligation on the phagocytic functions and morphology of the spleen in rabbits in which secondary hypersplenism was induced by splenic vein ligation (SVL). Thirty New Zealand-type rabbits were included in this study. The rabbits were separated into three groups of 10 subjects each. The first group underwent laparotomy, and the second and third groups underwent laparotomy + splenic vein ligation. At the end of the fourth week, the first and second groups underwent laparotomy while the third group underwent laparotomy + splenic artery ligation. At the end of the eighth week, 1 cc of blood was taken from all rabbits to determine hematological parameters. The rabbits were administered with 0.1 mCi/kg of Tc-99m sulfur colloid, and retention rates in the liver and spleen were determined. The spleens of the rabbits were removed and examined histopathologically. Median liver/spleen retention rates were found to be 26.2 count/pixel in the sham group, 29.1 count/pixel in group II and 55 count/pixel in group III. The retention rate in the spleen was significantly lower in group III (p = 0.0001). Leukocyte levels were similar among the groups while erythrocyte and thrombocyte levels were significantly lower in group II than in the other two groups (p = 0,0001). Histopathologically, wide congestion was observed in group II while extended fibrosis and necrosis were observed in the spleens of group III. Although the application of SAL in secondary hypersplenism cases reduces the severity of hypersplenism, it fails to improve the phagocytic function of the spleen.Öğe The relationship between perceived organizational justice and cyberloafing: Evidence from a public hospital in Turkey(2013) Ö?üt E.; Şahin M.; Demirsel M.T.The aim of this research is to try to determine the role of organizational justice in the occurrence of cyberloafing behaviours, which have started to become a major problem for companies, by emphasizing the importance of the perception of organizational justice. The relationship between the lack of organizational justice, which is one of the significant problems of organizations, and cyberloafing has been tried to be determined. After the theoretical study, the relationship between perceived organizational justice and cyberloafing in hospitals has been analysed and it has been aimed to contribute to the solution of this problem by making some suggestions for the employers.Öğe The role of ischemia modified albumin in the evaluation of hemodynamic changes in the splanchnic area during laparoscopic cholecystectomy [Laparoskopik kolesistektomi süresince splanknik sahadaki hemodinamik de?işikliklerin de?erlendirilmesinde iskemi modifiye albuminin rolü](2010) Köksal H.; Kurban S.; Şahin M.Purpose: Elevation of intraabdominal pressure by means of gas insufflation produces hemodynamic disturbances in the peritoneal viscera, leading to splanchnic ischemia. Recently, ischemia modified albumin (IMA) has been used to investigate conditions such as myocardial and skeletal muscle ischemia. The purpose of this clinical investigation is to determine the role of IMA in the evaluation of alterations in blood flow of the splanchnic area and abdominal viscera during laparoscopic cholecystectomy. Patients and Methods: Twenty two patients (F/M: 21/1) undergoing laparoscopic cholecystectomy (Group I) and 10 patients (F/M: 7/3) undergoing various surgical procedures under general an- estheasia (Group II) were studied. No patient had any cardiovascular disease. Blood samples for IMA were collected at preoperative and intraoperative periods. A rapid, colorimetric assay was used to measure serum IMA levels. Results: In Group I, the preoperative and intraoperative IMA levels were 0.59±0.16 absorbance units (ABSU) and 0.74±0.17 ABSU, respectively. The intraoperative IMA levels were higher than the preoperative levels (p=0.025). In Group II, the preoperative and intraoperative IMA levels were 0.43±0.12 ABSU and 0.52±0.15 ABSU, respectively. The difference was not statistically significant (p=0.22). The intraoperative IMA levels in Group I were higher than Group II (p=0.003).Conclusion: IMA, a new sensitive marker for ischemia, can be helpful for determining alterations in blood flow of the splanchnic area and abdominal viscera during laparoscopic cholecystectomy. cholecystectomy, splanchnic area.
