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Öğe Antimycotic activity of methanol extracts of sage (Salvia officinalis L.), Laurel (Laurus Nobilis L.) and Thyme (Thymbra spicata L.)(HAR KRISHAN BHALLA & SONS, 2008) Ünver, Ahmet; Arslan, Derya; Çetinkaya, Zafer; Özcan, Mehmet MusaInhibitory effects of methanol-water (90: 10; v/v) extract from sage (Salvia officinalis L.), laurel (Laurus nobilis L.) and thyme (Thymbra spicata L.) were tested in vitro on clinical isolates of eleven species of yeasts (C. krusei, C. clus, Rhodotorula rubra, C. albicans 10039, C. tropicalis, C. glabrata 70164, C. parasilosis, C. insane, C. rhodotonla, C. holmii and C. glabrata 13b). Preliminary experiment was carried out in vitro using the disc diffusion method to investigate antimycotic activity of the sage, laurel and thyme extracts. Thyme methanol extract showed very high antimycotic activity against all tested yeasts. Effect of laurel extract was as good as thyme extract for C. tropicalis at 40 ppm level. Generally, sage had no effect on the tested yeasts. Methanol extracts of thyme and laurel may be useful tools to control the yeasts growth.Öğe Antioxidant effect of essential oils of rosemary, clove and cinnamon on hazelnut and poppy oils(ELSEVIER SCI LTD, 2011) Özcan, Mehmet Musa; Arslan, DeryaAntioxidant effects of essential oils from rosemary (Rosmarinus officinalis), clove (Syzygium aromaticum) and cinnamon (Cinnamomum zeylanicum) were determined on hazelnut and poppy oils. These essential oils were added to the oils at concentrations of 0.25% and 0.5%. Butylated hydroxyanisole (BHA) at 0.02% level served as standard besides the control groups for comparison. The samples were stored 50 degrees C in darkness for 14 days. The antioxidant activity of the essential oils was determined by measuring peroxide values (meq O(2)/kg oil) at regular intervals. On the basis of peroxide value assay, the essential oils showed stronger antioxidant effect when compared to control groups. BHA was more effective than the essential oils, whilst it exhibited no antioxidative effect on the first few days of storage. Amongst the investigated essential oils, the cinnamon oil was the most effective on retarding lipid oxidation of crude oils, which was followed by clove and rosemary oils. (C) 2011 Published by Elsevier Ltd.Öğe Application of fuzzy expert system approach on prediction of some quality characteristics of grape juice concentrate (Pekmez) after different heat treatments(SPRINGER INDIA, 2011) İnan, Özlem; Arslan, Derya; Taşdemir, Şakir; Özcan, Mehmet MusaEffects of heat treatment on physicochemical characteristics and sensory properties of different fruit juice concentrates (pekmez) were studied. Apricot pekmez had the highest viscosity followed by mulberry and date pekmez. Apricot and date pekmez had higher scores for odour, taste and consistency than others. Hydroxymethyl furfural concentration of all pekmez samples increased after heat treatments. Samples heated at 75A degrees C showed highest L* values while at 65A degrees C the lowest mean L* values. L* values of all pekmez samples were similar while carob Pekmez had higher L* values. Also a development of the Fuzzy Expert System (FES) was made for prediction. Using the experimental values, FES model of the system was designed. Accordance was found with experimental and FES results when compared statistically. This study provides advantage for prediction possibility of unknown sub-values', which were not experimentally studied.Öğe Assessment of P-wave dispersion in children with atrial septal aneurysm(CAMBRIDGE UNIV PRESS, 2014) Arslan, Derya; Cimen, Derya; Guvenc, Osman; Oran, Bulent; Yilmaz, Fatma HilalBackground: This was a prospective controlled study to determine the P-wave duration and P-wave dispersion in patients with atrial septal aneurysm. Methods: A total of 41 children with atrial septal aneurysm, including 21 boys and 20 girls (mean age 11.85 +/- 3.8 years), and 32 controls, including 17 boys and 15 girls (mean age 12.3 +/- 2.9 years), were included. P-wave dispersion was calculated from the 12-lead electrocardiogram. Cardiac functions, morphology of the aneurysm, and left atrial diameter were measured using conventional echocardiography. The diagnosis of atrial septal aneurysm was made when the base of the aneurysms with an excursion ratio >= 25% was found on echocardiography. Results: There was no significant difference between the patient and control groups in demographic, clinical findings, and M-mode echocardiographic parameters. The P-wave dispersion in patients with atrial septal aneurysm was significantly longer compared with the control group (64.4 +/- 13.4 ms; p < 0.0001). Similarly, the the maximum duration of the P wave in the patient group was significantly longer compared with the control group (106.1 +/- 13.3 ms; p < 0.001). The P-wave duration and dispersion were not correlated with age, gender, systolic and diastolic blood pressure, or m-mode echocardiographic parameters. Conclusions: This study shows that P-wave dispersion is delayed in atrial septal aneurysm patients. Prolonged P-wave dispersion was determined to indicate electrical disturbance, and therefore it has an increased electrocardiographic risk of atrial arrhythmia in children with atrial septal aneurysm.Öğe Biochemical compositional and technological characterizations of black and white myrtle (Myrtus communis L.) fruits(SPRINGER INDIA, 2012) Hacışeferoğulları, Haydar; Özcan, Mehmet Musa; Arslan, Derya; Ünver, AhmetBiochemical and technological properties were determined in developing Myrtus communis L. fruits (myrtle) from Mersin to investigate potential uses. Completely ripe black and white fruits contained ash, crude protein, crude oil, water- and alcohol soluble extracts, tartaric, malic and citric acids, and minerals including Ca, K, P, Mg and Na. Proximate compounds (%) for black and white fruits were: 7.47 and 6.36 protein, 3.487 and 3.453 oil, 3.02 and 2.30 ash, 24.28 and 26.09 dry matter, respectively. Fruits were found to be rich in some minerals such as Ca (6719.88 mg/kg and 4676.14 mg/kg), K (22647.78 mg/kg and 18339.84 mg/kg), Mg (2145.19 mg/kg and 1408.88 mg/kg), Na (3336.16 mg/kg and 2976.59 mg/kg) and P (4336.07 mg/kg and 3927.4 mg/kg). Also, physical properties such as length (14.94 mm and 13.64 mm), mass (0.94 g and 0.94 g), geometric mean diameter (12.73 mm and 12.31 mm), sphericity (0.85 and 0.90), diameter (11.76 and 11.70), projected area (1.48 cm(2) and 1.65 cm(2)), kernel density (757.47 kg/m(3)and 752.09 kg/m(3)), porosity (41.41% and 39.05%), bulk density (426.50 kg/m(3) and 431.05 kg/m(3)), terminal velocity (8.42 m/s and 8.49 m/s), volume (1.32 mm(3) and 1.35 mm(3)), repture strenth (1.77 N and 2.06 N), static (0.26-0.33 and 0.20-0.28) and dynamic coefficient (0.22-0.29 and 0.17-0.24) of friction of black myrtle and white myrtle fruits species were measured at 75.72% and 73.91% moisture content levels, respectively. These results show that both myrtle fruits may be useful for the evaluation of dietary information in important food crops.Öğe Cardiovascular Adverse Effects of ActivityPromoting Video Games in Children with Heart Diseases(2013) Arslan, Derya; Oran, Bülent; Cøhan, Tuğba; Çimen, DeryaAmaç: Aktivite üreten video oyun sistemleri giderek daha popüler hale gelmektedir. Bu prospektif çalışmanın amacı kalp hastalığı olan çocuklarda, aktivite üreten video oyunlarının kardiyovasküler yan etkilerini araştırmaktır. Materyal ve Metot: Bu prospektif çalışma kalp hastalığı olan 20 çocuk ile yaş ve cinsiyet olarak uyumlu 20 sağlıklı kontrol bireyi ile gerçekleştirildi. Tüm hastalara elektrokardiyografi ve transtorasik ekokardiyografi yapıldı. Tüm hasta ve sağlıklı kontrol bireylerine 15 dakika boyunca aktivite üreten video oyunu oynatıldı. Katılımcıların video oyunu oynarken kalp hızı, solunum hızı ve kan basıncı ölçüldü. Bulgular: Video oyunu oynatılarak yüksek kalp ve solunum hızı, yüksek kan basıncı ortaya çıkarıldı. Video oyunu oynarken tahmin edilen kardiyovasküler yan etkiler gözlendi. En sık görülen semptomlar yorgunluk, baş dönmesi, bulantı ve göğüs ağrısı idi. Sonuçlar: Aktivite üreten video oyunlarının kalp hastalığı olan çocuklarda kardiyovasküler yan etkilerde artış gibi potansiyel bir dezavantajı olabilir. Bu video oyunlarını oynama süresi sınırlandırılmalıdır. Özellikle ciddi kalp yetmezliği ya da kardiyovasküler obstrüktif lezyonları olan çocuklar için ani ölüme neden olabileceği unutulmamalıdır.Öğe Cardiovascular MR imaging findings of total anomalous pulmonary venous connection to the portal vein in a patient with right atrial isomerism(SPRINGER WIEN, 2012) Koplay, Mustafa; Paksoy, Yahya; Erol, Cengiz; Arslan, Derya; Kivrak, Ali Sami; Karaaslan, SevimTotal anomalous pulmonary venous connection (TAPVC) is a rare congenital cardiovascular anomaly in which the pulmonary veins fail to join to the left atrium and drain directly to the right atrium or to one of the systemic veins. This anomaly is frequently seen together with complex cardiac anomalies especially as a part of right atrial isomerism syndrome. Atrial isomerism is called that the same morphological structure of both atria. We reported a very rare case demonstrating TAPVC between the portal vein and the pulmonary veins in a patient with right atrial isomerism by magnetic resonance imaging.Öğe Carpenter sendromu ve çift çıkışlı sağ ventrikül birlikteliği(2017) Güvenç, Osman; Çimen, Derya; Arslan, Derya; Güler, İbrahimCarpenter sendromu (Akrosefalopolisindaktili tip 2, OMIM 201000), nadir görülen ve otozomal resesif olarak geçen bir hastalıktır. Akrosefali, kraniyosinostoz, fasiyal asimetri polidaktili ve sindaktili, obezite, hipogonadizm, mental gerilik ve kornea opasitesi gibi anomalilerin yanında en sık olarak ventriküler septal defekt, patent duktus arteriyozus ve pulmoner stenoz olmak üzere doğuştan kalp hastalıklarıyla da birlikte olabilir. Çift çıkışlı sağ ventrikül, her iki büyük damarın tamamen veya büyük oranda morfolojik sağ ventrikülden çıktığı bir hastalıktır. Bildiğimiz kadarıyla bu sendromla birlikte çift çıkışlı sağ ventrikül hastalığı literatürde tanımlanmamıştır. Bu yazıda, Carpenter sendromu ve çift çıkışlı sağ ventrikül birlikteliği olan bir hasta sunuldu.Öğe Case Presentation: Approach To Acute Rheumatic Fever Patient With Hepatotoxicity Due To Acetylsalicylic Acid(GALENOS YAYINCILIK, 2017) Guvenc, Osman; Cimen, Derya; Aslan, Eyup; Emiroglu, Haldun; Arslan, Derya; Oran, BulentTreatment with acetylsalicylic acid is the first choice for arthritis and mild carditis of acute rheumatic fever which is a common disease in our country. There may be many adverse reactions during treatment. 10 year-old male patient diagnosed as acute rheumatic fever had hepatotoxicity due to acetylsalicylic acid therapy. This clinic manifestation has the possibility that can be seen always in pediatric cardiology practice. This case is presented due to limited literature on the treatment of patients with hepatotoxicity.Öğe Changes in chemical composition of some oils extracted from seeds roasted at different temperatures(WAGENINGEN ACADEMIC PUBLISHERS, 2015) Şimşek, E.; Özcan, Mehmet Musa; Arslan, Derya; Ünver, Ahmet; Kanbur, GülşahOil seeds are commonly used in cooking, frying and as salad oil and have commercial and economic importance. Since the seeds are roasted before pressing of the oil, changes occur in their composition; thus it is crucial to modify roasting process to minimise adverse effects. This study reflects the effects of different roasting temperatures (90, 150 and 210 degrees C for 10 min. in conventional oven) on the oil constituents and some chemical properties of oils from the seeds of sesame, sunflower, soybean, flaxseed and poppy along with comparison to those of unroasted corresponding seed oils. Lipids from roasted seeds of sesame, flax and soybean exhibited relatively higher viscosity and free fatty acids, than lipids from unroasted seeds. With an increase in roasting temperatures the colour of the oils were slightly darker even though the changes were not significant in most cases. The content of alpha- and gamma-tocopherols in oils (except soybean oil) gradually decreased as roasting temperature increased. beta-tocopherol was higher in the oils of roasted seeds, while the amount of delta-tocopherol showed different trends with roasting depending on the type of seeds. For sesame and poppy oils, after roasting at 210 degrees C, stearic and oleic acids showed higher percentages when compared to the levels in oils roasted at 90 and 150 degrees C.Öğe Characteristics of some almond kernel and oils(ELSEVIER SCIENCE BV, 2011) Özcan, Mehmet Musa; Ünver, Ahmet; Erkan, Esin; Arslan, DeryaThe proximate properties, the fatty acid and mineral contents of different almond kernel varieties were determined. The crude protein contents of kernels ranged between 12.7% (guara) and 16.3% (cristomorto). The oil yields from these kernels were established between 48.8% (cristomorto) and 55.7% (ferragnes). The acidity value of oils were found between 1.389 and 3.559%. In addition, peroxide values were established between 7.586 (nonpareil) and 15.590 mequiv./kg (cristomorto). The major fatty acids of almond kernel oils were oleic (72.5-79.9%), linoleic(13.5-19.8%) and palmitic acids (5.9-6.7%). The predominant mineral in most kernel was potassium (13.1-15.1 mg/100 g). The mineral contents of the kernels were established as 7.94-9.38 mg/100 g potassium, 2.9-4.0 mg/100 g magnesium and 1.84-2.94 mg/100 g calcium. From the results of the present study, it can be concluded that the kernels of almond varieties are being potential sources of valuable oil which might be used for edible and other industrial applications. (C) 2010 Elsevier B.V. All rights reserved.Öğe Chemical Composition of the Essential Oil of Salvia Cryptantha(Har Krishan Bhalla & Sons, 2010) Saadia, Zrira; Özcan, Mehmet Musa; Bağcı, Yavuz; Ünver, Ahmet; Arslan, Derya; Durak, Gülşah; Er, Fatih; Sağlam, CoşkunThe essential oil for the present investigation was obtained from the air-dried leave + flowers of Salvia cryptantha as described in the experimental. Composition of water-distilled essential oils of S. cryptantha growing wild in Turkey were analysed by GC and GC-MS. At least 16 compounds were isolated and identified, corresponding to 98.5 % of the oil. The major compounds were camphor (25.6 %), 1,8-cineole (20.3 %), beta-pinene (12.8 %), n-hexane (10.6 %), heptane (8.9 %), borneol (5.1 %) and alpha-pinene (4.1 %). The oils consisted of monoterpenic hydrocarbons and oxygenated monoterpenes.Öğe CHEMICAL COMPOSITION, TOTAL PHENOLIC AND MINERAL CONTENTS OF ENTEROMORPHA INTESTINALIS (L.) KUTZ. AND CLADOPHORA GLOMERATA (L.) KUTZ. SEAWEEDS(WILEY-BLACKWELL, 2011) Akköz, Cengiz; Arslan, Derya; Ünver, Ahmet; Özcan, Mehmet Musa; Yılmaz, BetülIn this study, crude ash, protein, oil, mineral and total phenolic contents, and antioxidant properties of Enteromorpha intestinalis (L.) Kutz. and Cladophora glomerata (L.) Kutz. seaweeds were determined. The samples were collected from Actgol Lake in Karapinar town of Konya in Turkey. The crude ash, crude oil and protein content of E. intestinalis and Cladophora glomerata were 1.92% and 2.44%, 1.63% and 2.48%, 15.02% and 14.13%, respectively. The phenolic content of aqueous solutions was lower than methanolic solutions. The free radical scavenging activity (2,2-diphenyl-1-picrylhydrazyl) was also higher in methanolic solutions. Phenolic content and free radical scavenging activity of aqueous and methanolic extracts of C. glomerata were higher than E. intestinalis. Both algae were rich in minerals but, while using these algae as a food or feed, attention must be paid on their heavy metal content.Öğe Co-occurrence of Carpenter syndrome and double outlet right ventricle(TURKISH SOC CARDIOLOGY, 2017) Guvenc, Osman; Cimen, Derya; Arslan, Derya; Guler, IbrahimCarpenter syndrome (acrocephalopolysyndactyly type 2, OMIM 201000) is a rarely seen autosomal recessive disorder. In addition to abnormalities such as acrocephaly, craniosynostosis, facial asymmetry, polydactyly and syndactyly, obesity, hypogonadism, mental retardation, and corneal opacity, it may frequently be accompanied by congenital heart diseases such as ventricular septal defect, patent ductus arteriosus and pulmonary stenosis. Double outlet right ventricle is a defect in which both major arter-ies originate in the morphological right ventricle. To the best of our knowledge, this is the first report in the literature of double outlet right ventricle disease in combination with Carpenter syndrome.Öğe Coarctation of the Aorta Presenting with Fever and Abdominal Pain: A Case Report(Selçuk Üniversitesi, 2022) Şimşek, Nazmi; Arslan, Derya; Soran, Mustafa; Sütçü, MuratAortic coarctation is among the congenital heart disease which can easily be diagnosed in infancy and childhood by means of a deliberate physical examination and echocardiography. Children without a prompt diagnosis are represented with several complications that depend on the severity of coarctation. It is of vital importance to perform stent implantation, balloon dilatation or surgical repair as soon as possible after the diagnosis, because severe complications may emerge in aortic coarctation. The present report delineates the case of a six-year old patient who was presented with fever and abdominal pain, and diagnosed with echocardiography to have aortic coarctation.Öğe Çocuklarda Nadir Görülen Bir Hastalık: Goltz Sendromu(2016) Güvenç, Osman; Bilgiç, Özlem; Çimen, Derya; Aslan, Eyüp; Arslan, Derya; Oran, BülentGoltz sendromu (Fokal dermal hipoplazi), mezoektodermal dokuyu tutan ve çok nadir görülen bir hastalıktır. Deri lezyonları ile birlikte iskelet sistemi, dental ve oküler anomaliler, hastaların az bir kısmında da kalp ve böbrek anomalileri görülebilmektedir. Makalede, Goltz sendromu tanısı alan, biküspit aort kapağı ve buna bağlı aort kapak darlığı ve yetmezliği olan beş yaşındaki kız hasta olgu olarak sunuldu ve seyrek görülen bu hastalık, son literatür bilgileri eşliğinde tartışıldı.Öğe Çocuklarda Salbutamol Zehirlenmesine Yaklaşım:Olgu Sunumu(2017) Güvenç, Osman; Çimen, Derya; Aslan, Eyüp; Arslan, DeryaKısa etkili inhale beta 2 mimetik bir ilaç olan salbutamol, bronkospazm ve solunum sıkıntısı durumlarında çok sık kullanılmaktadır ama ülkemizde intihar amaçlı alımı nadir görülen bir durumdur. Salbutamole bağlı komplikasyonlar iyi bilinmektedir ve terapotik dozlarda da ortaya çıkabilir. İlaca bağlı toksikasyon geliştiğinde hiperaktivite, tremor, konvülziyon, hiperglisemi, hipokalemi, hipomagnezemi, laktik asidoz, hipotansiyon, hipertansiyon, konjestif kalp yetmezliği, miyokard iskemisi, atriyal ve ventriküler ektopik atımlar, atriyal aritmiler, QT uzaması ve ventriküler taşikardi gibi aritmiler ile ani kardiyak ölüm ortaya çıkabilir. Bu makalede, intihar amaçlı olarak salbutamolün tablet formundan 200 mgr kullanan 15 yaşındaki bir hasta sunuldu ve literatür bilgileri eşliğinde çocuklarda salbutamol zehirlenmesine yaklaşım tartışıldıÖğe Comparative Essential Oil Composition and Antifungal Effect of Bitter Fennel (Foeniculum Vulgare Ssp Piperitum) Fruit Oils Obtained During Different Vegetation(Mary Ann Liebert Inc, 2006) Özcan, Mehmet Musa; Chalchat, Jean Claude; Arslan, Derya; Ateş, Ayşe; Ünver, AhmetThe chemical composition of the flower and unripe and ripe fruits from fennel (bitter) (Foeniculum vulgare ssp. piperitum) has been examined by gas chromatography and gas chromatography-mass spectrometry. The main identified components of the flower and unripe and ripe fruit oils were estragole (53.08%, 56.11%, and 61.08%), fenchone (13.53%, 19.18%, and 23.46%), and a-phellandrene (5.77%, 3.30%, and 0.72%), respectively. Minor qualitative and major quantitative variations for some compounds of essential oils were determined with respect to the different parts of F. vulgare. The oils exerted varying levels of antifungal effects on the experimental mycelial growth of Alternaria alternata, Fusarium oxysporum, and Rhizoctonia solani. The 40 ppm concentrations of fennel oils showed inhibitory effect against mycelial growth of A. alternaria, whereas 10 ppm levels were ineffective. The analyses show that fennel oils exhibited different degrees of fungistatic activity depending on the doses.Öğe The Comparison of the Chemical Composition, Sensory, Phenolic and Antioxidant Properties of Juices from Different Wheatgrass and Turfgrass Species(UNIV AGR SCI & VETERINARY MED CLUJ-NAPOCA, 2016) Özköse, Abdullah; Arslan, Derya; Acar, AyşenurWheatgrass juice is mainly derived from the common wheat Triticum aestivum L. The present study focused on the analysis of the potential of different perennial turfgrass species in grass juice production by determining certain compositional characteristics. The effects of fertilisers on the plants and the cutting time on some chemical constituents and antioxidant potential of grass juices were addressed. The juices from the different species of grasses, such as T. durum, T. aestivum, Lolium perenne L., Festuca arundinacea Schreb. were obtained by pressing. DPPH (1, 1dipheny1-2-picrylhydrazyl) radical scavenging activity, elemental composition, total chlorophylls, total carotenes, tocopherols, vitamin C, total phenols, viscosity and the colour profiles of the grass juice samples were analysed. Water-soluble dry matter, protein, total phenols, flavonoids and vitamin E (especially Durum cultivar) content were found to be higher in the juices of Triticum species as compared to the other grasses. Turfgrass species demonstrated higher concentrations of oil (in grass), vitamin C (unfertilised samples), chlorophyll (except L. perenne local) and major elements. The pressing of turfgrass was an easy process. Such perennial grass varieties have advantages over the Triticum species in terms of having higher concentrations of vitamin C (unfertilised samples) and major elements. The results of sensory analysis suggested that L. perenne (cultivar) is the most promising cultivar in terms of obtaining pressed grass juice.Öğe Coronary Arteriovenous Fistula in a Child Presenting with Chest Pain(DERMAN MEDICAL PUBL, 2016) Arslan, Derya; Cimen, Derya; Oran, Bulent; Aygul, NazifCoronary arteriovenous fistula is an incidental finding in 0.1% to 0.2% of coronary angiograms. A 15-year-old famale patient presented with a three years history of chest pain on exertion. Echocardiography was performed previously and a small muscular ventricular septal defect was detected. The electrocardiogram was normal sinus rhythm together with normal axis. On echocardiography, left ventricular function was normal and there was continuous flow into the right ventricle. Therefore, coronary angiography was performed for considering the coronary artery fistula. Coronary artery fistula was observed between the first septal perforating branch of the left anterior descending coronary artery with right ventricle. The patient's clinical follow-up was decided since a significant shunt could not be identified.
