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    Epidural Administration of Midasolam for Chronic Central Pain and Spasticity in Spinal Cord Injured Patients
    (1997) Özerbil, O. M.; Duman, A.; Yosunkaya, A.; Bayram, A.; Üstün, M. E.
    In the patients with spinal cord injury (SCI) chronic pain and spasticity affect significantly both the efficacy of rehabilitation and the quality of life. Recently it was shown that intrathecally and epidurally administered midasolam has analgesic and antispatic effects in both animals and humans so that it constitutes an alternative to be used in patients with SCI. In this study, four paraplegics who suffered from chronic central pain and spasticity in their lower extremities were given midasolan 6 times daily (dose 40 ?g/kg dose dissolved in 10 ml normal saline) via lumbar epidural catheter using pain management provider. Spasticity was monitored by means of a modified Ashwort scale, and pain evaluation was performed by face scale and VAS. The patients were hospitalized at least for two weeks and were observed for the efficacy of the drug. Although epidural administration of midasolam relieved both central pain and spasticity, it's efficacy on central pain was more pronounced. There were no significant side effects is any patient. We propose that midasolam may be given by epidural catheter or implantable drug pump for the treatment of central pain and/or spinal spasticity in spinal cord injured patients.
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    Examination of Coronary Heart Disease and Risk Factors in Asymptomatic Adults in Central Anatolia [eine Untersuchung Der Koronaren Herzerkrankung und Der Risikofaktoren Bei Asymptomatischen Erwachsenen in Zentralanatolien]
    (1995) Gönen, M. S.; Cin, V. G.; Gök, H.; Bayram, A.; Telli, H. H.
    The coronary heart disease and its risk factors were investigated in Konya district which is situated in central Anatolia, Turkey. In this study 280 asymptomatic persons, who were middle aged and over (?40), were selected at random from Bozkir, a small town of Konya, which shows a homogenous structure of population. Cardiovascular system of all the cases were examined. ECG and teleradiography were taken. In 54 cases (19.3% ) hypertension, in 11 cases (3.9%) hyperglycemia and in 58 male cases (59.8%) smoking were found. Obesity was seen in 17% of male and 27% of female cases. Hypercholesterolemia in 12% of cases and hypertriglyceridemia in 7.4% of cases were also seen. In 40 cases, coronary heart disease was determined. Incidence of hypertension was increasing with age, but the rate of cigarette-smoking was not changed. Under the light of positive results of the struggle with the reversible major risk factors, periodic examinations in cases with high risk, medical and preventive treatment procedures were pointed out clearly as important issues for the physician.
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    Examination of Coronary Heart-disease and Risk-factors in Asymptomatic Adults in Centralanatolia
    (F K SCHATTAUER VERLAG GMBH, 1995) Gönen, M.S.; Cin, V.G.; Gök, H.; Bayram, A.; Telli, H.H.
    The coronary heart disease and its risk factors were investigated in Konya district which is situated in central Anatolia, Turkey. in this study 280 asymptomatic persons, who were middle aged and over (greater than or equal to 40), were selected at random from Bozkir, a small town of Konya, which shows a homogenous structure of population. Cardiovascular system of all the cases were examined. ECG and teleradiography were taken. In 54 cases (19.3%) hypertension, in 11 cases (3.9%) hyperglycemia and in 58 male cases (59.8%) smoking were found. Obesity was seen in 17% of male and 27% of female cases. Hypercholesterolemia in 12% of cases and hypertriglyceridemia in 7.4% of cases were also seen. in 40 cases, coronary heart disease was determined. Incidence of hypertension was increasing with age, but the rate of cigarette-smoking was not changed. Under the light of positive results of the struggle with the reversible major risk factors, periodic examinations in cases with high risk, medical and preventive treatment procedures were pointed out clearly as important issues for the physician.