Yazar "Biçer, Mürsel" seçeneğine göre listele
Listeleniyor 1 - 9 / 9
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Akut Yüzme Egzersizi Yaptırılan Diyabetik Sıçanlarda Intraperitoneal Çinko Sülfat Uygulamasının Kas Dokusundaki Lipid Peroksidasyonuna Etkisi(Selçuk Üniversitesi, 2018 Eylül) Biçer, Mürsel; Ünsal, SadettinAmaç: Bu çalışmanın amacı, streptozotosin ile diyabet oluşturulmuş akut yüzme egzersizi yaptırılan sıçanlarda çinko uygulamasının kas dokusundaki lipid peroksidasyonu ve antioksidan kapasite üzerindeki etkisinin araştırılmasıdır. Gereç ve Yöntem: Spraque-Dawley cinsi 80 adet erişkin erkek ratlar kullanılan çalışmada. deney hayvanları eşit sayıda 8 gruba ayrıldı: Grup 1, genel kontrol. Grup 2, çinko uygulanan kontrol. Grup 3, çinko uygulanan diyabetli kontrol. Grup 4, yüzme kontrol. Grup 5, çinko uygulanan yüzme. Grup 6, çinko uygulanan diyabetli yüzme. Grup 7, diyabetli yüzme. Grup 8, diyabet grubu. Diyabet oluşturmak için hayvanlara 40 mg/kg dozunda intraperitoneal (ip) streptozotosin (STZ) enjekte edildi. Enjeksiyonlar 24 saat sonra aynı dozda tekrarlandı. Son enjeksiyonlardan 6 gün sonra kan glukozu 300 mg/dl ve üzerinde olan hayvanlar diyabetik olarak kabul edildi. Hayvanlara 4 hafta boyunca 6 mg/kg/gün ip çinko sülfat verildi. Dört hafta süren çalışmanın bitiminde deney hayvanlarından dekapitasyonla alınan kas doku örneklerinde MDA (nmol/gram/ protein) ve GSH (mg/dl/gram protein) düzeyleri tayin edildi. Bulgular: Kas dokusundaki en yüksek MDA değerleri grup 4 ve 7’de elde edildi. Grup 5 ve 6’nın kas MDA seviyeleri grup 4 ve 7’den düşük, diğer grupların tamamından yüksekti. Grup 5 ve 6 en yüksek kas GSH değerlerine sahipti. Grup 4’ün aynı parametresi grup 5 ve 6’dan düşük diğer grupların tamamından daha yüksekti. Kas dokusundaki en düşük GSH düzeyleri Grup 7 ve 8’de elde edildi. Sonuç: Çalışmanın sonuçları diyabetik sıçanlarda zorlu yüzme egzersizinin yol açtığı kas dokusundaki lipit peroksidasyonu üzerinde intraperitoneal çinko sülfat uygulamasının koruyucu rolü olduğunu göstermektedir.Öğe Effect of melatonin on element distribution in the liver tissue of diabetic rats subjected to forced exercise(COMENIUS UNIV, 2015) Biçer, Mürsel; Akil, Mustafa; Baltacı, Abdulkerim Kasım; Moğulkoç, Rasim; Sivrikaya, Abdullah; Akkuş, HasanThe objective of the present study was to investigate the effects of melatonin supplementation on elements in the liver of diabetic rats subjected to acute swimming exercise. Eighty adult male rats were equally divided into eight groups. Group 1, general control. Group 2, melatonin-supplemented control. Group 3, melatonin-supplemented diabetic control. Group 4, swimming control. Group 5, melatonin-supplemented swimming. Group 6, melatonin-supplemented diabetic swimming. Group 7, diabetic swimming. Group 8, diabetic control. Liver tissue samples were analyzed for lead, cobalt, molybdenum, chrome, sulphur, magnesium, manganese, sodium, potassium, phosphorus, copper, iron, calcium, zinc, selenium. The highest cobalt, chrome values were found in the groups 7, 8 and the groups 5, 6 respectively. Groups 3 and 7 had the highest copper values. Iron and potassium values were higher in the groups 1 and 4. Group 6 had increased magnesium value, and groups 6, 7, 8 were found to have the highest manganese levels. The highest lead values were found in the groups 5 and 6. Group 6 had the highest selenium levels. The highest zinc levels were established in 1 and 2. Groups 1, 2, 5 and 6 were found to have the highest calcium values. The results of our study indicate that melatonin supplementation in diabetes and forced exercise significantly alters the element metabolism in the liver (Tab. 3, Ref. 33). Text in PDF www.elis.sk.Öğe The effect of selenium supplementation on elements distribution in liver of rats subject to strenuous swimming(COMENIUS UNIV, 2013) Sivrikaya, Abdullah; Akil, Mustafa; Biçer, Mürsel; Kılıç, Mehmet; Baltacı, Abdulkerim Kasım; Moğulkoç, RasimThe present study aims to explore how selenium supplementation affects the element distribution in the liver tissue of rats subjected to strenuous swimming exercise. Thirty-two Spraque-Dawley male rats were equally divided into the four groups: Group 1, normal control group. Group 2, selenium-supplemented, non-swimming (0.6 mg/kg/day sodium selenite) group. Group 3, swimming, no supplementation group. Group 4, swimming, selenium-supplemented (0.6 mg/kg/day sodium selenite) group. After one month, the animals were decapitated and liver tissue samples were collected to determine the levels of lead, cobalt, boron, molybdenum, chromium, sulfur, magnesium, sodium, potassium, phosphorus, copper, iron, zinc and selenium. The chromium, molybdenum, iron, sodium and potassium values were higher in the swimming groups, relative to controls. Group 3 had significantly lower lead levels (p<0.001). The highest cobalt levels were obtained in the Group 1 and that of the Group 2 was higher than in the Groups 3 and 4. The boron values in the Group 3 were higher than those in all other groups. The copper and magnesium levels were higher in the Groups 3 and 4, compared to the Groups 1 and 2. The highest phosphorus levels were found in the Group 1. The highest selenium and zinc values were obtained in the Group 2 and those of the Group 4 were higher than in the Groups 1 and 3. Group 1 had higher selenium and zinc levels than the Group 3. The results of the present study demonstrated that selenium-supplemented rats subjected to strenuous swimming exercise had distinct elements distribution in liver tissue. Also, selenium supplementation offsets the decrease in zinc levels in rats subjected to vigorous swimming (Tab. 3, Ref. 20). Full Text in PDF www.elis.sk.Öğe Effect of zinc supplementation on lipid peroxidation and lactate levels in rats with diabetes induced by streptozotocin and subjected to acute swimming exercise(COMENIUS UNIV, 2012) Biçer, Mürsel; Günay, Mehmet; Baltacı, Abdulkerim Kasım; Üney, Kamil; Moğulkoç, Rasim; Akil, MustafaObjective: The present study aims to explore the effect of zinc supplementation on lipid peroxidation and lactate levels in rats having diabetes induced by streptozotocin and subjected to acute swimming exercise Method: A total of 80 adult male rats of Sprague-Dawley type were equally allocated to 8 groups: Group 1, general control. Group 2, zinc-supplemented group. Group 3, zinc-supplemented, diabetic group. Group 4, swimming control group. Group 5, zinc-supplemented swimming group. Group 6, zinc-supplemented diabetic swimming group. Group 7, diabetic swimming group. Group 8, diabetic group. At the end of the 4-week study, blood samples were collected to determine MDA, GSH, GPx, SOD, lactate and zinc levels. Results: The highest MDA values were found in group 7 and 8 (p<0.001). GSH values in groups 5 and 6 were higher (p<0.001). The highest GPx values were established in groups 2, 5 and 6 (p<0.001). SOD values were the highest in groups 5 and 6 (p<0.001) and lowest in groups 2, 3 and 8 (p<0.001). The highest plasma lactate levels were found in group 7 (p<0.001). The highest zinc levels were obtained in groups 1,2 and 5 (p<0.001), and the lowest zinc levels were found in groups 7 and 8 (p<0.001). Conclusion: Results of the study reveal that zinc supplementation prevents the increase in free radical formation, suppression of antioxidant activity and muscle exhaustion, all of which result from diabetes and acute exercise. Zinc supplementation may contribute to health and performance in diabetes and acute exercise (Tab. 2, Fig. 1 Ref. 47). Full Text in PDF www.elis.sk.Öğe Effects of Electromyostimulation Training on Body Composition(Selçuk Üniversitesi, 2019 Nisan) Kirişçioğlu, Mehmet; Biçer, Mürsel; Pancar, Zarife; Doğan, İlkayThe purpose of this study is to examine the variables such as weight, body fat percentage and amount, lean body mass (FFM) and body mass index (BMI) occurred on body as a result of realization of voluntary contraction and involuntary contraction together with training by electromyostimulation (EMS) system. 41 voluntary women joined the study as treatment (n=20) and control group (n=21). a 25-minute training program was arranged for treatment group with Bodytec EMS device twice a week for 8 weeks. Training was done as strength and durability exercises for 12 minutes, cardio exercises for 8 minutes and active rest for 5 minutes. Ages, genders, lengths, weights, fat percentages, lean body masses and body mass indexes of groups were measured both whole and regional, and then these parameters were compared before and after treatment. Measurements were donetwice as pre-test and post-test. Tanita bc 418 body analyzer belongs to Bio Electricity Impedans method was used for all measurements. In data analysis, 2*2 Repeated Measures Varians Analysis (Repeated Measures ANOVA) was used to compare pre-test and post-test measures. Statistical results were evaluated at p?.05 significance level. Consequently, p?.05 significance level was identified in favor of the post-tests analyzes of pre-tests and last tests of experimental group in body weight , BMI , fat % (body fat ratio) ,values of fat mass (amount of fat), value of right foot fat percent , value of right foot fat mass , value of left foot fat percent , value of left foot fat mass ,body fat mass in value of right-left arms fat percent. Statistically, p?.05 significance level was determined between pre-tests and post-tests of control group's measurements. It was seem to occur significant changes on body compositation values of experimental group as a result of EMS training.Öğe Examination on the anthropometric features and somatotypes of the male children at the age of 16(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2011) Polat, Yahya; Biçer, Mürsel; Patlar, Süleyman; Akil, Mustafa; Günay, Mehmet; Çelenk, ÇağrıObjectives.-The aim of the study is to examine the anthropometric values and the somatotypes of male children from different branches in physical education lessons and regular movement training. Methods.-Two hundred and eighteen volunteer subjects at the age of 16, namely, 68 soccer players, 89 persons practising fitness and 70 sedentary have participated in the study. In the research, sitting height, crawl length, body width parameters, body environment and sonnatotypic parameters of the subjects are measured. In this work, the highest humeral width value is achieved by the soccer group, where it is found to be no different from the fitness group (P > 0.05) and to be significantly higher than the sedentary group (P < 0.05). When femur width parameter is examined, it is determined that the soccer group is higher than the other two groups and that the fitness group is significantly higher than the sedentary group. In the study, while the highest endomorph value is obtained from sedentary group, it is found to be significantly higher than the other two groups (P < 0.05). While the highest mesomorph value is achieved from soccer group and the lowest value is achieved from sedentary group, it is determined that each of these three groups is significantly different from one another (P < 0.05). While the highest ectomorph value is achieved from fitness group (P < 0.05), it is found to be significantly higher than the other two groups (P < 0.05). Conclusions.-Consequently, it can be said that the soccer players have more optimal dimension, environment and somatotypical structure when compared to those practising fitness and the sedentary group (P < 0.05). (C) 2010 Elsevier Masson SAS. All rights reserved.Öğe Protective effect of melatonin on lipid peroxidation in various tissues of diabetic rats subjected to an acute swimming exercise(COMENIUS UNIV, 2012) Biçer, Mürsel; Akil, Mustafa; Baltacı, Abdulkerim Kasım; Moğulkoç, Rasim; Sivrikaya, Abdullah; Günay, Mehmet; Akkuş, HasanBackground: The present study aimed to explore the effect of melatonin administration on lipid peroxidation in various tissues of rats with streptozocin induced diabetes and subjected to an acute swimming exercise. Methods: The study used 80 adult male rats, which were equally allocated to 8 groups: Group 1, general control; Group 2, melatonin-administered control; Group 3, melatonin-administered diabetic control; Group 4, swimming control; Group 5, melatonin-administered swimming; Group 6, melatonin-administered diabetic swimming; Group 7, diabetic swimming; Group 8, diabetic control. Diabetic rats were administered 3 mg/kg/day ip melatonin for 4 weeks. At the end of the study, the animals were decapitated to collect samples from liver, lung and spleen tissues, which were then analyzed to determine levels of liver MDA (nmol/gram/protein) and GSH (mg/g/protein). Results: The highest MDA values in liver, lung and spleen tissues were obtained in the Group 7. The values in the Group 8 were lower than those in the Group 7, but higher than in all other groups. The Group 5 and 6 had the highest liver, lung and spleen GSH values. Conclusion: Results obtained from the study indicate that the increase in free radical production and the inhibition of antioxidant activity in diabetes and acute exercise are both prevented by melatonin administration (Tab. 2, Ref. 30). Full Text in PDF www.elis.sk.Öğe Selenium prevents lipid peroxidation in liver and lung tissues of rats in acute swimming exercise(COMENIUS UNIV, 2015) Akil, Mustafa; Gürbüz, Ümit; Biçer, Mürsel; Halifeoğlu, I.; Baltacı, Abdulkerim Kasım; Moğulkoç, RasimBackground: Selenium, which is critical for human health, is necessary for various metabolic processes, including thyroid hormone metabolism, protection against oxidative stress, and immune function. Objective: The present study aims to examine how selenium administration affects lipid peroxidation in liver and lung tissues of rats subjected to acute swimming exercise. Methods: The study included 32 Spraque-Dawley adult male rats divided into Group 1 (general control), Group 2 (selenium-administered), Group 3 (swimming), and Group 4 (selenium-administered swimming). MDA and GSH levels were determined in liver and lung tissues. Results: The highest MDA values in the liver and lung tissues were found in group 3 in the study. MDA value in group 4 was higher than those in groups 1 and 2. Group 4 had the highest liver and lung GSH levels. GSH levels in Group 3 were higher than those in groups 1 and 2. Conclusion: Results of the study indicate that acute swimming exercise causes lipid peroxidation in liver and lung tissues, while selenium administration prevents free radical formation by increasing antioxidant activity (Tab. 2, Ref. 26). Text in PDF www.elis.sk.Öğe Selenium supplementation prevents lipid peroxidation caused by arduous exercise in rat brain tissue(COMENIUS UNIV, 2011) Akil, Mustafa; Biçer, Mürsel; Menevşe, Esma; Baltacı, Abdulkerim Kasım; Moğulkoç, RasimBackground: The objective of the present study is to examine how selenium supplementation affects lipid peroxidation in the brain tissue of rats subjected to acute swimming exercise. Methods: The study was carried out on 32 Spraque-Dawley adult male rats, which were allocated equally to four groups, namely general control (Group 1), selenium-supplemented control (0.6 mg/kg/day sodium selenite) (Group 2), swimming control (Group 3), and selenium-supplemented swimming group (6 mg/kg/day sodium selenite) (Group 4). Selenium supplementations were carried out by intraperitoneal (i.p.) route for four weeks. At the end of supplementation, animals in groups 3 and 4 were subjected to acute swimming. Brain tissue samples were collected from decapitated animals to determine malondialdehyde (MDA) levels using a spectrophotometer according to "Schimadzu-1601, Japan" Uchiyama and Mihara and GSH levels using a spectrophotometer according to Ellmann. Results: The highest MDA values in the brain tissue were obtained in Group 3 (p<0.001). MDA values in Group 4 were higher than those in Groups 1 and 2 (p<0.001). Brain tissue MDA values in Groups 1 and 2 did not differ. Group 4 had the highest brain GSH levels (p<0.001). Brain tissue glutathione (GSH) levels in Group 3 were higher than those in Groups 1 and 2 (p<0.001). Conclusion: Results of the study indicate that acute swimming exercise in rats increased the lipid peroxidation in the brain tissue of rats, while selenium supplementation prevented the free-radical formation by enhancing the antioxidant activity (Tab. 1, Ref. 24). Full Text in free PDF www.bmj.sk.