Yazar "Celik, I" seçeneğine göre listele
Listeleniyor 1 - 6 / 6
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Approximal carious lesion depth assessment with insight and ultraspeed films(OPERATIVE DENTISTRY INC, 2005) Gungor, K; Erten, H; Akarslan, ZZ; Celik, I; Semiz, MThis study evaluated the efficiency of a new E/F-speed film, Insight, at the determination of approximal carious lesion depths compared with Ultraspeed. Radiographs of 80 extracted human molars and premolars were taken with both films under standardized conditions. The presence or absence of caries and depth of lesions was determined by three observers using a predetermined scale. The actual status of each surface was determined histologically. Observer responses were assessed with the Gamma measure of association test. Differences between the observers' agreement levels were not significant. The efficiency of Insight and Ultraspeed at true depth diagnosis was found to be 54.9%; 55.8% and Gamma values were found to be 0.883 and 0.922, respectively, at p<0.001. The difference between the two films was not statistically significant (p=0.852). This study suggested that there was no statistically significant difference between the two films at detecting the depths of approximal carious lesions.Öğe Effects of aflatoxin B-1 on the development of chicken thymus and blood lymphocyte alpha-naphthyl acetate esterase activity(UNIV GHENT, 2005) Sur, E; Celik, IIn this study, the depressive effects of AFB(1) on the embryonic development of chicken thymus were determined by histological methods and by histochemical demonstration of alpha-naphthyl acetate esterase (ANAE) enzyme. ANAE positivity frequencies of peripheral blood lymphocytes (PBL) were also determined. Embryonic stages were determined according to the Hamburger-Hamilton (H-H) scale. Thymic development was quite similar on day 7 of incubation in all control and AFB(1) groups. In contrast, the development was substantially impaired and retarded on day 10 of incubation in the 20 and 40 ng/egg AFB(1) groups. The ANAE positivity was first detected on the 18(th) day of incubation in a minority (2%) of PBL. The proportions of PBL and their ANAE positivity frequencies were significantly (P < 0.05) lower in AFB(1) treated groups than in the controls on the day of hatching.Öğe Effects of dietary boron supplementation on some biochemical parameters, peripheral blood lymphocytes, splenic plasma cells and bone characteristics of broiler chicks given diets with adequate or inadequate cholecalciferol (vitamin D-3) content(TAYLOR & FRANCIS LTD, 2005) Kurtoglu, F; Kurtoglu, V; Celik, I; Kececi, T; Nizamlioglu, M1. The effects of 5 and 25 mg/kg boron supplementation of diets with inadequate (6.25 mu g/kg) or adequate (50 mu g/kg) cholecalciferol (vitamin D-3) content on some biochemical parameters, tibia characteristics, peripheral blood lymphocyte and splenic plasma cell counts of broilers were investigated. 2. Supplementation of the diet with boron affected plasma concentrations of boron, iron, copper and zinc and also tibia boron, zinc and calcium concentrations but did not have any effect on tibia iron or copper concentrations or tibia ash and tibia weight values. 3. Boron supplementation caused significant increases in splenic plasma cell count but decreased the proximal and distal tibia growth plate widths. There was no effect of boron supplementation on peripheral blood alpha-naphthyl acetate esterase (ANAE) content. Whole blood haematocrit and haemoglobin counts were significantly increased by boron supplementation but there were no effects on leucocyte ratios such as eosinophil, basophil, monocyte, lymphocyte and thrombocyte. 4. In general, the findings of the present study support the hypothesis that boron has an important biological role that affects the mineral metabolism of animals by influencing both biochemical and haematological mechanisms.Öğe Expression of Fas and Fas-ligand and analysis of argyrophilic nucleolar organizer regions in squamous cell carcinoma: relationships with tumor stage and grade, and apoptosis(CHURCHILL LIVINGSTONE, 2005) Guler, N; Uckan, S; Celik, I; Oznurlu, Y; Uckan, DThe aim of this study was to investigate whether levels of Fas and Fas-ligand (Fas-L) expression in oral and oropharyngeal squamous cell carcinomas (SCCs) are associated with tumor stage and grade, and to assess whether parameters related to argyrophilic nucleolar organizer regions (AgNORs) correlate with apoptosis in SCC cells and adjacent normal epithelium. Fifty-two specimens taken from the tumoral and neighboring normal tissues of 26 patients with oral and oropharyngeal SCC were analyzed for Fas/Fas-L expression, and 24 specimens from 12 patients for AgNOR parameters. Seventeen (65%) of the tumors were Fas and/or Fas-L-positive (by immunohistochemistry). A significant positive correlation was found between Fas/FasL expression and clinical tumor stage (P < 0.01). Mean AgNOR number per nucleus, AgNOR size and the percentage area of each nucleus occupied by AgNORs (percent of nuclear area) were significantly increased in the SCC cells (4.49 +/- 1.28, 4.48 +/- 1.42, 5.56 +/- 1.22, respectively) when compared with the control neighboring squamous epithelial cells (2.58 +/- 0.61, 1.64 +/- 0.59 and 4.35 +/- 0.62%, respectively) (P < 0.01). A significant positive correlation was found between the AgNOR parameters and Fas/ Fas-L expression as apoptotic markers in the tumoral cells of SCC (P < 0.05). There was also a significant positive correlation between the AgNOR parameters and the grading of tumors (P < 0.05). In conclusion, AgNOR count was a strong proliferation marker in patients with SCC, and Fas and Fas-L staining was useful in tumor grading.Öğe A light microscopic study on the uptake and transportation route of carbon particles in the canine palatine tonsil(ECOLE NATIONALE VETERINAIRE TOULOUSE, 2001) Baykan, M; Celik, I; Gezici, M; Donmez, HH; Eken, E; Sur, E; Ozkan, YUptake of carbon particles through the epithelium and their transportation route in the canine palatine tonsils were investigated by light microscopy. Reticular and non reticular regions were distinguished in both oral surface and crypt epithelium. Particle ingestion was peculiar to the reticular epithelium. The ingested material was first transported mainly in phagocytosed form to the subepitelial connective tissue and following into the deeper regions, to the bases of lymphoid follicles through the interfollicular tissue. Any free or phagocytosed particles were not observed at the germinal centers of the follicles. It was concluded that the tonsils might operate as a primary sampling area for restricted number of antigens which the animal is exposed. On the other hand, they may contribute to the common mucosal immune system via trafficking of both antigen primed lymphocytes and antigen phagocytosed macrophages those were frequently observed in the luminae of venous and lymphatic sinuses, located at the center of the tonsil.Öğe Responses of acrylamide-treated rat bladders(COMENIUS UNIV, 2013) Atalık, Kısmet Esra Nurullahoğlu; Okudan, Nilsel; Belviranlı, Muaz; Esen, H.; Yener, Y.; Celik, IObjective: Acrylamide (ACR) is a chemical used in many industries around the world and more recently was found to be formed naturally in foods cooked at high temperatures. ACR was shown to be a neurotoxicant, reproductive toxicant, and carcinogen in animal species. The aim of the present study is to evaluate the influence of ACR treatment on urinary bladder responses to carbachol (10(-9)-3x10(-4) M) and potassium chloride (KCl; 5-100 mM), each of them causes receptor-dependent and receptor-independent contractions, respectively. We also examined the role of gender in these responses. Material and methods: Rats of both genders were divided into three groups as follows: (1) Control animals (2) ACR-I; ACR-treated (2 mg/kg-d for 90 days) (3) ACR-II; ACR-treated (5 mg/kg-d for 90 days). Results: In rats treated with ACR, the EC50 values of carbachol and KCl, but not the maximal response, to both agents were significantly higher than in control group. Histopathological parameters such as edema, congestion, inflammatory cells, microvascular proliferation, fibrosis, eosinophils, mast cells and epithelial damage were all higher in the ACR-treated group than in the controls. Conclusions: These results demonstrate for the first time that ACR-treatment can induce urinary bladder injury (Tab. 4, Fig. 4, Ref. 30). Full Text in PDF www.elis.sk.
