Effects of aflatoxin B-1 on the development of chicken thymus and blood lymphocyte alpha-naphthyl acetate esterase activity
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Dosyalar
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
UNIV GHENT
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, the depressive effects of AFB(1) on the embryonic development of chicken thymus were determined by histological methods and by histochemical demonstration of alpha-naphthyl acetate esterase (ANAE) enzyme. ANAE positivity frequencies of peripheral blood lymphocytes (PBL) were also determined. Embryonic stages were determined according to the Hamburger-Hamilton (H-H) scale. Thymic development was quite similar on day 7 of incubation in all control and AFB(1) groups. In contrast, the development was substantially impaired and retarded on day 10 of incubation in the 20 and 40 ng/egg AFB(1) groups. The ANAE positivity was first detected on the 18(th) day of incubation in a minority (2%) of PBL. The proportions of PBL and their ANAE positivity frequencies were significantly (P < 0.05) lower in AFB(1) treated groups than in the controls on the day of hatching.
Açıklama
Anahtar Kelimeler
Kaynak
VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT
WoS Q DeÄŸeri
Q4
Scopus Q DeÄŸeri
Cilt
74
Sayı
6
