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Öğe Hypokalemic paralysis due to thyrotoxicosis accompanied by Gitelman's syndrome(Medknow Publications, 2015) Baldane S.; Ipekci S.H.; Celik S.; Gundogdu A.; Kebapcilar L.A 35-year-old male patient was admitted with fatigue and muscle weakness. He had been on methimazole due to thyrotoxicosis for 2 weeks. Laboratory tests showed overt hyperthyroidism and hypokalemia. Potassium replacement was started with an initial diagnosis of thyrotoxic hypokalemic periodic paralysis. Later on, despite the euthyroid condition and potassium chloride treatment, hypokalemia persisted. Further investigations revealed hyperreninemic hyperaldosteronism. The patient was considered to have Gitelman's syndrome (GS) and all genetic analysis was done. A c. 1145C>T, p.Thr382Met homozygote missense mutation located on solute carrier family 12, member gene 3, exon 9 was detected and GS was confirmed.Öğe Lower urinary tract symptoms in diabetic women with and without urinary incontinence(Blackwell Publishing, 2014) Yilmaz S.D.; Bal M.D.; Celik S.; Beji N.K.; Dinccag N.; Yalcin O.Determination of lower urinary tract symptoms (LUTS) in diabetic women with and without urinary incontinence (UI) and its related factors is significant to define essential measures associated with prevention. The aim of this study is to compare the features of diabetes mellitus (DM) in diabetic women with and without UI, and to investigate LUTS and its related factors. Applying to the Diabetes Department of Istanbul Medical Faculty, Istanbul University (IMFIU) between May and December 2011, 77 diabetic women with the complaint of UI and 88 diabetic continent women were enrolled into the descriptive study. Data were collected via a questionnaire defining socio-demographic and clinical features, and The Bristol Female Lower Urinary Tract Symptoms (BFLUTS-SF) after obtaining an approval from the ethical board of the institution. It was found that diabetic continent women and those with UI showed no statistically significant difference regarding age, BMI and duration of DM (p>0·05). Among women with UI, levels of fasting blood glucose and HbA1c were significantly higher (p<0·05). The total BFLUTS-SF and subscale scores of women with UI were significantly higher than continent women (p<0·05). A significant correlation was determined between total BFLUTS-SF score, and fasting blood glucose (r=0·185), BMI (r=0·192), HbA1c (r=0·245), complaint of vaginal itching (r=0·629) and exposure to frequent vaginal infections (r=0·701; p<0·05). It was found that increased HbA1c was effective on total BFLUTS-SF. Consequently, diabetic women with UI show high rates of fasting blood glucose and HbA1c, compared to diabetic women without UI. Therefore, diabetic women should meticulously be followed and evaluated in terms of LUTS by health care professionals. © 2014 John Wiley & Sons Ltd.Öğe The use of stereophotogrammetry in oral surgery: Measurement of area changes after secondary epithelization and grafting vestibuloplasties(2012) Ozturk A.; Dolanmaz D.; Celik S.; Isik K.; Karabork H.; Yildiz F.; Yakar M.Objective: Stereophotogrammetry (SPT) is a method in which three-dimensional coordinates are calculated from multiple two-dimensional projections. The purpose of this study was to compare the surface area changes between the secondary healing and grafting vestibuloplasty techniques in the mandible by using a stereophotogrammetric technique (SPT). Patients and Methods: Thirteen patients were included in this study: six patients were managed by using full-thickness skin or palatal mucosa grafts (two full-thickness palatal mucosal grafts and four full-thickness skin grafts); the remaining seven patients, who did not accept a second surgery for graft harvesting, underwent secondary epithelization vestibuloplasties. Postoperative changes of surgical areas were measured by using SPT. Statistical Analyses: The Wilcoxon (intragroup comparisons) and Mann-Whitney U (intergroup comparisons) tests were used for analysis of data. Results: In the grafting vestibuloplasty group, the surface area gain was statistically significant (P < 0.05). In the secondary epithelization vestibuloplasty group, there was no significant difference (P > 0.05), with even decrease of surface area being noted in some cases. Conclusion: SPT is a valid method for measurement of intraoral soft tissue changes.