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Öğe Assessment of dermal wound healing and in vitro antioxidant properties of Avena sativa L.(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2011) Akkol, Esra Küpeli; Suntar, I.; Orhan, I. Erdogan; Keles, H.; Kan, A.; Coksari, G.Avena sativa L (Poaceae) has been reported to have traditional utilization against skin diseases and inflammation. Therefore, in this study, the n-hexane, ethyl acetate, ethanol, and water extracts of A. sativa were investigated for their wound healing and antioxidant activities. Total phenol and flavonoid contents of the extracts were established spectrophotometrically. For the wound healing activity, linear incision and circular excision models on rats and mice were evaluated with a standard ointment Madecassol. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, ferrous ion-chelating, and ferric-reducing antioxidant power (FRAP) assays. Significant wound healing activity was observed with the ointment formulation of the ethanol extract at 1% concentration. The histopathological examination results also supported the outcome of both linear incision and circular excision wound models. All of the extracts exerted low antioxidant activity in the applied assays. The present study provides a scientific evidence for the traditional usage of A. sativa in the management of wound healing. (C) 2011 Published by Elsevier Ltd.Öğe Effects of different drying methods on caffeic acid derivatives content of Echinacea purpurea cultivated in Turkey(GEORG THIEME VERLAG KG, 2011) Coksari, G.; Gulpinar, A.; Kan, Y.; Kartal, M.[Abstract not Available]Öğe Elemental compositions of Echinacea purpurea, E. pallida radix and herba cultivated in Turkey(GEORG THIEME VERLAG KG, 2011) Kan, Y.; Coksari, G.; Guner, S. T.; Kose, Y. B.; Demirci, F.[Abstract not Available]
