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Öğe Relation of serum leptin and insulin-like growth factor-1 levels to intima-media thickness and functions of common carotid artery in children and adolescents with type 1 diabetes(WILEY, 2004) Atabek, ME; Kurtoglu, S; Demir, F; Baykara, MBackground and aim: Leptin and insulin-like growth factor-1 (IGF-1) have been suggested to be involved in the pathogenesis of atherosclerosis. The aim of this study was to evaluate the relationship between serum leptin, IGF-1 and intima-media thickness (IMT) and functions of common carotid artery (CCA) in children and adolescent patients with type 1 diabetes. Material and methods: Serum leptin and IGF-1 levels were measured in 45 diabetic patients (23 girls and 22 boys). Age, diabetes duration as well as major cardiovascular risk factors, including anthropometric and metabolic parameters, were matched between girls and boys. The relation of serum leptin and IGF-1 levels to CCA structure and functions were measured by ultrasonography as IMT, cross-sectional compliance (CSC), cross-sectional distensibility (CSD), diastolic wall stress (DWS) and incremental elastic modulus (IEM). Results: Serum leptin levels of diabetic girls were higher than those in the boys (21.8 +/- 14.5 mug/l vs 8.9 +/- 10.6 mug/l, p = 0.002). However, the difference for serum IGF-1 levels was not significant between diabetic girls and boys (240.7 +/- 96.8 ng/ml vs 234.7 +/- 93.2 ng/ml; p > 0.05). In all subjects, leptin levels were correlated with CSC (p = 0.04), CSD (p = 0.04) and IEM (p = 0.01), and IGF-I levels were only correlated with CSC (p = 0.01). Leptin did not show any correlation with ultrasonographic measurements in both girls and boys separately. IGF-1 was correlated with CSC (p = 0.001), CSD (p = 0.002) and IEM (p < 0.001) in boys but not in girls. In a multivariate regression model, IGF-1 emerged as independent correlates for mean CSD and IEM in boys but not in girls. Conclusion: Serum leptin and IGF-1 levels in children and adolescent patients with type 1 diabetes are associated with functions of common carotid artery, and the association of IGF-1 levels is influenced by sex.Öğe Some nutritional and technological properties of garlic (Allium sativum L.)(ELSEVIER SCI LTD, 2005) Haciseferogullari, H; Ozcan, M; Demir, F; Calisir, SThe nutrients and physical properties were measured in developing Allium sativum L. bulbs from Kastamonu (Taskopru) to investigate potential uses. Completely ripe bulbs contained crude protein, crude oil, crude energy, crude fiber, ash, dimethyl sulphite (DMS) and essential oil and minerals including K, P, Mg, Na, Ca, Fe, etc. Crude protein, DMS and essential oil contents were determined as 17.2%, 1779 mu cg/kg and 0.14%, respectively. In addition, K (21,378.84 mg/kg), P (6009.37 mg/kg), Mg (1056.15 mg/kg), Na (532.78 ppm) and Ca (363.61 ppm) were reported such as the major minerals in garlic bulbs. Also, technological properties such as diameter of whole garlic, mass, segment number of whole garlic, length of whole garlic, width, thickness, geometric mean diameter, sphericity, projected area, volume, bulk density, segment density, porosity, terminal velocity and hardness were established. The mean mass, mass weight of 1000 garlic segment, length of segment, diameter of whole garlic, geometric mean diameter, sphericity, projected area, volume, bulk density, porosity and hardness of segments were measured as 32.81 g, 2383.8 g, 27.24 mm, 46.51 mm, 15.15 mm, 0.559,4.54 cm(2), 2245.64 mm(3), 478.75 kg/m(3), 54.16% and 13.78 N, respectively. Also, static and dynamic coefficient of friction for garlic segments were established on a galvanized sheet, an iron sheet and plywood. These values for static and dynamic coefficient were found as 0.416-0.352; 0.472-0.406 and 0.541-0.481, respectively. The physical properties of equipment used must be know for planting, harvesting, transportation, storage and other processing. (c) 2004 Elsevier Ltd. All rights reserved.Öğe Some physico-mechanic and chemical properties of capers (Capparis ovata Desf. var. canescens (Coss.) Heywood) flower buds(ELSEVIER SCI LTD, 2004) Ozcan, M; Haciseferogullari, H; Demir, FThe physico-mechanic and chemical properties were established in developing Capparis ovata Desf. var. canescens (Coss.) Heywood buds from Konya (Selcuklu) to investigate potential uses. Raw flower buds contained crude ash, crude oil, crude protein, crude fiber, total carotenoid, crude energy, water- and ether-soluble extract, dimethyl sulfite (DMS) and essential oil. In addition, physical properties such as length and diameter of buds, mass of buds, projected area, volume, porosity, bulk density, bud density, thermal velocity, hardness were measured. (C) 2004 Elsevier Ltd. All rights reserved.