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Öğe The effect of different doses of zinc supplementation on serum element and lactate levels in elite volleyball athletes(UNIV SOUTH BOHEMIA, 2017) Eskici, Günay; Günay, Mehmet; Baltacı, Abdülkerim Kasım; Moğulkoç, RasimThe present study aims to examine the effect of different doses of zinc administration on serum element metabolism and fatigue. The study registered 20 female elite athletes. The subjects were divided into two groups in equal numbers. Group supplemented with 220 mg/day zinc sulfate. Group supplemented with 440 mg/day zinc sulfate. Athletes who were already engaged in their daily training routines were put to a 20-m shuttle run test to create fatigue before and after supplementation. Blood samples were collected from the subjects for a total of 7 times, before and after zinc supplementation and during rest and after exercise within one-week intervals over the course of the 4-week supplementation. The blood samples collected as such were analyzed to determine serum magnesium, phosphorus and calcium, zinc, iron, copper, and selenium, and plasma lactate. Both exercise and zinc supplementations significantly elevated magnesium, calcium, and iron levels for 4 weeks. Pre-supplementation exercise elevated plasma lactate levels, while zinc supplementation led to a fall in plasma lactate. The results of the present study indicate that zinc-supplementation for 4 weeks may have a positive impact on athletic performance by delaying fatigue. (C) 2016 Published by Elsevier Sp. z o.o. on behalf of Faculty of Health and Social Sciences, University of South Bohemia in Ceske Budejovice.Öğe Effect of Long-Term Intraperitoneal Zinc Administration on Liver Glycogen Levels in Diabetic Rats Subjected to Acute Forced Swimming(HUMANA PRESS INC, 2011) Biçer, Mürsel; Günay, Mehmet; Akil, Mustafa; Avunduk, Mustafa Cihat; Moğulkoç, Rasim; Baltacı, Abdülkerim KasımThis study aims to examine the effect of zinc administration on liver glycogen levels of rats in which diabetes was induced with streptozotocin and which were subjected to acute swimming exercise. The study was conducted on 80 adult Sprague-Dawley male rats, which were equally allocated to eight groups: group 1, general control; group 2, zinc-administrated control; group 3, zinc-administrated diabetic control; group 4, swimming control; group 5, zinc-administrated swimming; group 6, zinc-administrated diabetic swimming; group 7, diabetic swimming; group 8, diabetic control group. In order to induce diabetes, animals were injected with 40 mg/kg intraperitoneal (ip) streptozotocin. The injections were repeated in the same dose after 24 h. Animals which had blood glucose at or above 300 mg/dl 6 days after the last injections were accepted as diabetic. Zinc was administrated ip for 4 weeks as 6 mg/kg/day per rat. Hepatic tissue samples taken from the animals at the end of the study were fixed in 95% ethyl alcohol. Cross sections of 5 A mu m thickness, taken by the help of a microtome from the tissue samples buried in paraffin, were placed on a microscope slide and stained with periodic acid-Schiff and evaluated by light microscope. All microscopic images were transferred to a PC and assessed with the help of Clemex PE3.5 image analysis software. The lowest liver glycogen levels in the study were obtained in groups 3, 4, 6, 7, and 8. Liver glycogen levels in group 5 were higher than groups 3, 4, 6, 7, and 8, but lower than groups 1 and 2 (p < 0.05). Groups 1 and 2 had the highest liver glycogen levels. The results obtained from the study indicate that liver glycogen levels which dropped in acute swimming exercise were restored by zinc administration and that diabetes induced in rats prevented the protective effect of zinc.Öğe Effect of Vitamin C Supplementation on Lipid Peroxidation and Lactate Levels in Individuals Performing Exhaustion Exercise(ANNALS APPLIED SPORT SCIENCE, 2017) Patlar, Süleyman; Baltacı, Abdülkerim Kasım; Moğulkoç, Rasim; Günay, MehmetBackground. Exercise has significant affects on free radical production. Objective. The objective of the present study was to explore the effect of vitamin C supplementation on lipid peroxidation and lactate levels in sedentary individuals who performed exhaustion exercised. Methods. 10 healthy sedentary male athletes participated to study. They were supplemented with 300 mg oral vitamin C (L-ascorbic acid, Ester-C Plus 500 mg, Solgar-USA) and subjected to acute exhaustion exercise by fatigue developed one time a week for 4 weeks. Exhaustion exercises were carried out until exhaustion developed according to Bruce protocol once a week for 4 weeks. Blood samples were collected from the subjects four times, at the beginning and at the end of the supplementation and before and after exercise, over the 4-weeks study period. The samples were used to analyze MDA, GSH, GSH-Px, CAT, SOD and NO levels by using ELISA colorimetric method and plasma lactate levels by an autoanalyzer device. Results. Exhaustion MDA, GSH, GSH-Px, CAT, SOD and NO levels measured both before and after supplementation were higher than resting levels (p<0.05). MDA, NO and lactate levels that were elevated in exhaustion before supplementation decreased significantly after vitamin C supplementation (p<0.05). Conclusion. The results of our study indicate that the increase in free radical production and lactate levels due to by 4-week exhaustion exercise were offset by vitamin C supplementation. It can be argued in conclusion that supplementation of physiologic doses of vitamin C may be useful for athlete health and performance.Öğe Effect of Zinc Supplementation on Antioxidant Activity in Young Wrestlers(HUMANA PRESS INC, 2010) Kara, Ersan; Günay, Mehmet; Cicioğlu, İbrahim; Özal, Mehmet; Kılıç, Mehmet; Moğulkoç, Rasim; Baltacı, Abdulkerim KasımThis study aims to examine the effect of zinc supplementation on free-radical formation and antioxidant system in individuals who are actively engaged in wrestling as a sport. The study registered a total of 40 male subjects, of whom 20 were wrestlers and 20 were sedentary individuals. The subjects were equally allocated to four groups: group 1, zinc-supplemented sportsmen group; group 2, sportsmen group without supplementation; group 3, zinc-supplemented sedentary group; group 4, sedentary group without supplementation. Blood samples were collected from all subjects twice, once at the beginning of the study and once again at the end of 8-week procedures. The blood samples collected were analyzed to determine the levels of malondialdehyde (MDA), serum glutathione (GSH), serum glutathione peroxidase (GPx) activity, serum superoxide dismutase (SOD) activity (ELISA colorimetric method) and zinc (colorimetric method). No difference was found between MDA levels of the study groups in the beginning of the study. The highest MDA value at the end of the study was obtained in group 4 (p < 0.01). MDA levels in group 2 were established to be significantly higher than those in groups 1 and 3 (p < 0.01). GSH level, GPx, and SOD activities and zinc level measured in the beginning of the study were not different between groups. Measurements performed at the end of the study showed that groups 1 and 3 (zinc-supplemented groups) had the highest GSH level, GPx, and SOD activities and zinc level (p < 0.01). These parameters were not different in the groups without supplementation (groups 2 and 4). Results obtained at the end of the study indicate that zinc supplementation prevents production of free radicals by activating the antioxidant system. In conclusion, physiologic doses of zinc supplementation to athletes may beneficially contribute to their health and performance.Öğe Effect of zinc supplementation on lipid peroxidation and lactate levels in rats with diabetes induced by streptozotocin and subjected to acute swimming exercise(COMENIUS UNIV, 2012) Biçer, Mürsel; Günay, Mehmet; Baltacı, Abdulkerim Kasım; Üney, Kamil; Moğulkoç, Rasim; Akil, MustafaObjective: The present study aims to explore the effect of zinc supplementation on lipid peroxidation and lactate levels in rats having diabetes induced by streptozotocin and subjected to acute swimming exercise Method: A total of 80 adult male rats of Sprague-Dawley type were equally allocated to 8 groups: Group 1, general control. Group 2, zinc-supplemented group. Group 3, zinc-supplemented, diabetic group. Group 4, swimming control group. Group 5, zinc-supplemented swimming group. Group 6, zinc-supplemented diabetic swimming group. Group 7, diabetic swimming group. Group 8, diabetic group. At the end of the 4-week study, blood samples were collected to determine MDA, GSH, GPx, SOD, lactate and zinc levels. Results: The highest MDA values were found in group 7 and 8 (p<0.001). GSH values in groups 5 and 6 were higher (p<0.001). The highest GPx values were established in groups 2, 5 and 6 (p<0.001). SOD values were the highest in groups 5 and 6 (p<0.001) and lowest in groups 2, 3 and 8 (p<0.001). The highest plasma lactate levels were found in group 7 (p<0.001). The highest zinc levels were obtained in groups 1,2 and 5 (p<0.001), and the lowest zinc levels were found in groups 7 and 8 (p<0.001). Conclusion: Results of the study reveal that zinc supplementation prevents the increase in free radical formation, suppression of antioxidant activity and muscle exhaustion, all of which result from diabetes and acute exercise. Zinc supplementation may contribute to health and performance in diabetes and acute exercise (Tab. 2, Fig. 1 Ref. 47). Full Text in PDF www.elis.sk.Öğe The effect of zinc supplementation on Max Vo(2) and lactate levels in sedentary people(BIOINTERFACE RESEARCH APPLIED CHEMISTRY, 2018) Kılıç, Mehmet; Baltacı, Abdülkerim Kasım; Günay, Mehmet; Okudan, Nilsel; Moğulkoç, RasimResults of previous studies have shown that exercise influences zinc metabolism. The importance of zinc intake by diet in athletes has been emphasized and it has been argued that zinc deficiency in the diet can have unfavorable effects on performance. The present study aims to investigate how zinc supplementation affects Max VO2 and lactate levels in sedentary people. The study included 10 male students who were not actively involved in sports. All subjects were supplemented with oral zinc sulfate (3mg/kg/day) for 4 weeks. Max VO2 and lactate levels of all subjects were determined before and after zinc supplementation. Max VO2 values of the subjects as measured after 4 weeks of zinc supplementation were numerically higher than the values measured before the supplementation, but the two values were not statistically different. Lactate levels, on the other hand, were found significantly lower after the supplementation, when compared to the levels before supplementation (p<0,05). Results of our study demonstrate that 4-week zinc supplementation leads to a significant decrease in lactate levels and delays exhaustion. Zinc supplementation can improve muscle strength and metabolism in physical activity. Consequently, physiological doses of zinc supplementation can be useful for performance.Öğe The effect of zinc supplementation on the urinary excretion of elements in female athletes(UNIV KARACHI, 2016) Eskici, Günay; Günay, Mehmet; Baltacı, Abdülkerim Kasım; Moğulkoç, RasimThis study was carried out to find out how oral zinc supplementation to elite athletes affects the element changes in the urine. The study registered 10 female athletes who were on the women's volleyball team of Gazi University Sports Club and whose mean age, weight, and height were 14.2 +/- 0.42 years, 59.8 +/- 7.79kg and 173.6 +/- 6.15 cm. The study protocol was approved by the local ethics committee. The athletes who continued their daily routine training sessions (6 days/week) were supplemented with 220mg/day oral zinc sulfate for 4 weeks. In order to induce exhaustion, the subjects were put to a 20-meter shuttle run test before and after supplementation. A total, 7 times urine samples were collected follows as pre and post exercise before the start of the experiment and at the end (4 times), at the end of first, second and third week (3 times). Urinary levels of magnesium, phosphorus, and calcium (mg/dl), as well as zinc, copper, and selenium ( mu g/dl) were analyzed in the atomic emission device (ICP-MS). Arithmetic means and standard errors of the data were calculated. Kruskal Wallis test was used to determine differences between weeks. Values for which p<0,05 were considered significant. When compared to resting values, urinary excretion of copper and selenium decreased in exercise (p<0,05), but increased with zinc supplementation (p<0,05). Pre- and post-supplementation exercise resulted in reduced urinary zinc excretion (p<0,05). Zinc supplementation increased urinary zinc excretion in one-week intervals over the course of 4 weeks (p<0,05), and reduced selenium levels (p<0,05). When zinc is supplemented to athletes, the relation between the duration and dose of supplementation is important. The results of the study indicated that zinc does not have any negative effect on the urinary excretion of the concerned elements. It can thus be concluded that athletes may benefit from zinc support.Öğe Effects of Exercise and Zinc Supplementation on Cytokine Release in Young Wrestlers(HUMANA PRESS INC, 2011) Kara, Ersan; Özal, Mehmet; Günay, Mehmet; Kılıç, Mehmet; Baltacı, Abdülkerim Kasım; Moğulkoç, RasimThe present study aims to examine the effect of zinc supplementation on the release of some cytokines in young wrestlers actively involved in wrestling. A total of 40 male subjects of the same age group were included in the study: half were wrestlers and the other half were not involved in sports. The subjects were equally divided into four groups and treated during an 8-week period as follows: group 1, zinc-supplemented athletes; group 2, non-supplemented athletes; group 3, zinc-supplemented sedentary subjects, and group 4, non-supplemented sedentary group. Blood samples were taken from each subject at the beginning and at the end of the study period. The serum tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2), and interpheron-gamma levels (IFN-gamma) were determined using the enzyme-linked immunosorbent assay method. At the beginning of the study, there were no significant differences of the measured parameters between the four study groups. At the end of the study, the levels of TNF-alpha, IL-2, and IFN-gamma were significantly higher in the two zinc-supplemented groups compared to those that did not receive supplementation, regardless of the activity status (p < 0.01).Öğe Elements in Sera of Elite Taekwondo Athletes: Effects of Vitamin E Supplementation(HUMANA PRESS INC, 2011) Patlar, Süleyman; Boyalı, Ekrem; Baltacı, Abdülkerim Kasım; Moğulkoç, Rasim; Günay, MehmetMany researchers have emphasized the relation between nutrition and development and sustaining performance. Two methods are commonly employed to identify the interaction between physical activity and nutrition. The first consists of administering food with a variety of contents to people engaged in physical activity and observing their performance responses, and the other is concerned with determining the effects of physical activity on nutrition. Therefore, it can be said that there has been a growing interest in the explorations into the relation between exercise and vitamins, minerals, and elements. The present study reports the effects of 6 weeks administration of 300 mg/day vitamin E on the distribution of serum elements in elite taekwondo athletes. Seven male athletes, mean ages 22.1 +/- 0.5 years weighing on average 66.4 +/- 2.4 kg were included in the study. The athletes had been practicing taekwondo for 10-12 years. Resting blood samples were collected in duplicate before and after supplementation for determination of serum levels of cobalt, boron, cadmium, chromium, nickel, manganese, sulfur, copper, iron, zinc, phosphorus, sodium, potassium, and calcium. Supplementation resulted in significant increases of all elements relative to values before supplementation (p < 0.001), with the exception of boron and sulfur, which remained without change. The results of the present study demonstrate that vitamin E supplementation crucially influences the element and mineral metabolism in elite athletes.Öğe Examination on the anthropometric features and somatotypes of the male children at the age of 16(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2011) Polat, Yahya; Biçer, Mürsel; Patlar, Süleyman; Akil, Mustafa; Günay, Mehmet; Çelenk, ÇağrıObjectives.-The aim of the study is to examine the anthropometric values and the somatotypes of male children from different branches in physical education lessons and regular movement training. Methods.-Two hundred and eighteen volunteer subjects at the age of 16, namely, 68 soccer players, 89 persons practising fitness and 70 sedentary have participated in the study. In the research, sitting height, crawl length, body width parameters, body environment and sonnatotypic parameters of the subjects are measured. In this work, the highest humeral width value is achieved by the soccer group, where it is found to be no different from the fitness group (P > 0.05) and to be significantly higher than the sedentary group (P < 0.05). When femur width parameter is examined, it is determined that the soccer group is higher than the other two groups and that the fitness group is significantly higher than the sedentary group. In the study, while the highest endomorph value is obtained from sedentary group, it is found to be significantly higher than the other two groups (P < 0.05). While the highest mesomorph value is achieved from soccer group and the lowest value is achieved from sedentary group, it is determined that each of these three groups is significantly different from one another (P < 0.05). While the highest ectomorph value is achieved from fitness group (P < 0.05), it is found to be significantly higher than the other two groups (P < 0.05). Conclusions.-Consequently, it can be said that the soccer players have more optimal dimension, environment and somatotypical structure when compared to those practising fitness and the sedentary group (P < 0.05). (C) 2010 Elsevier Masson SAS. All rights reserved.Öğe Ödünç iş ilişkisi(Selçuk Üniversitesi Sosyal Bilimler Enstitüsü, 2007) Günay, Mehmet; Uşan, M. FatihKüresellesme, gün geçtikçe artan uluslararası rekabet ve teknolojideki hızlı gelismeler, hayatın diger alanlarında oldugu gibi çalısma hayatında da bir takım yenilikleri ve degisiklikleri beraberinde getirmistir. Küresellesme, uluslar arası rekabet ve yeni teknolojik gelismeler, isgücüne gereksinimi azaltmıs ayrıca isverenler ve isçiler arasında normal tipteki is iliskilerinden farklı esneklik temeline dayanan yeni tipte is iliskileri ortaya çıkmıstır. Esneklik temeline dayanarak ortaya çıkan yeni tipteki is iliskilerinden bir tanesi de ödünç is iliskisidir. Ödünç is iliskisi; bir isverenin kendisine hizmet sözlesmesiyle baglı isçisini, onun da rızasını almak kosuluyla belirli ve geçici bir süreligine is görme edimini yerine getirmek üzere baska bir isverenin emrine vermesiyle olusan is iliskisidir. Bu tezde 4857 sayılı is Kanunu hükümleri çerçevesinde ?Ödünç iş iliskisi? kavramı ele alınacak ve bu iliskinin kurulması, hüküm ve sonuçlarıyla birlikte açıklanacaktır.Öğe Protective effect of melatonin on lipid peroxidation in various tissues of diabetic rats subjected to an acute swimming exercise(COMENIUS UNIV, 2012) Biçer, Mürsel; Akil, Mustafa; Baltacı, Abdulkerim Kasım; Moğulkoç, Rasim; Sivrikaya, Abdullah; Günay, Mehmet; Akkuş, HasanBackground: The present study aimed to explore the effect of melatonin administration on lipid peroxidation in various tissues of rats with streptozocin induced diabetes and subjected to an acute swimming exercise. Methods: The study used 80 adult male rats, which were equally allocated to 8 groups: Group 1, general control; Group 2, melatonin-administered control; Group 3, melatonin-administered diabetic control; Group 4, swimming control; Group 5, melatonin-administered swimming; Group 6, melatonin-administered diabetic swimming; Group 7, diabetic swimming; Group 8, diabetic control. Diabetic rats were administered 3 mg/kg/day ip melatonin for 4 weeks. At the end of the study, the animals were decapitated to collect samples from liver, lung and spleen tissues, which were then analyzed to determine levels of liver MDA (nmol/gram/protein) and GSH (mg/g/protein). Results: The highest MDA values in liver, lung and spleen tissues were obtained in the Group 7. The values in the Group 8 were lower than those in the Group 7, but higher than in all other groups. The Group 5 and 6 had the highest liver, lung and spleen GSH values. Conclusion: Results obtained from the study indicate that the increase in free radical production and the inhibition of antioxidant activity in diabetes and acute exercise are both prevented by melatonin administration (Tab. 2, Ref. 30). Full Text in PDF www.elis.sk.Öğe Yaşlıların fiziksel performans test skoruna göre fiziksel uygunluk düzeylerinin belirlenmesi(2008) Günay, Mehmet; Şenel, Ömer; Karacan, Selma; Çolakoğlu, Filiz; Cicioğlu, İbrahim; Güzel, Atalay NevinGiriş: Bu çalışmanın amacı; Ankara ilindeki devlete bağlı huzur ve bakım evlerinde yaşayan 60 ve üzeri yaşlardaki bireylerin Fiziksel Performans Test (FPT) protokolü ile fiziksel uygunluk düzeylerinin belirlenmesidir. Gereç ve Yöntem: Araştırmaya, test protokolünün uygulamasını engelleyecek veya kısıtlayabilecek sağlık problemi olmayan, 57'si kadın 50'si erkek olmak üzere toplam 107 kişi gönüllü olarak katılmıştır. Katılımcıların yaş grupları 60-69, 70-79 ve 80 ve üzeri olarak belirlenerek üç grup oluşturulmuştur. Araştırmaya katılan gruplara bazı fiziksel uygunluk testleri ile FPT uygulanmıştır. Bulgular: Verilerin analizi sonucunda; yaşlanma ile birlikte özellikle kadınlarda fiziksel uygunluk değerlerinde anlamlı düşüşlerin olduğu, aynı yaş gurubundaki erkek-kadın karşılaştırılması sonucunda, kan basınçları ile istirahat kalp atım sayıları dışındaki diğer parametrelerde 0.05 anlamlılık düzeyinde genellikle erkek grupların daha iyi olduğu, 70-79 yaş grubu kadınların esneklik değerlerinin ise aynı yaş grubundaki erkeklere göre anlamlı düzeyde yüksek olduğu tespit edilmiştir (p0.05). 80 ve üzeri yaşlardaki kadınlarda toplam FPT puanının diğer yaş gruplarına göre anlamlı derecede düşük olduğu belirlenmiştir (p0.05). Sonuç: Yaş ilerledikçe fiziksel uygunluğa ait yetilerin azaldığı ve bu kayıpların kadınlarda erkeklerden daha fazla olduğu gözlenmiştir.
