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Öğe Activity of Essential Oils and Individual Components against Acetyl-and Butyrylcholinesterase(2008) Orhan I.; Şener B.; Kartal M.; Kan Y.We have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fully-mature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical fertilizers), two from Mentha piperita L. and M. spicata L. (organic fertilizer), two from Lavandula officinalis Chaix ex Villars (cultivated using organic and chemical fertilizers), two from Ocimum basilicum L. (green and purple-leaf varieties cultivated using only organic fertilizer), four from Origanum onites L., O. vulgare L., O. munitiflorum Hausskn., and O. majorana L. (cultivated using organic fertilizer), two from Salvia sclarea L. (organic and chemical fertilizers), one from S. officinalis L. (organic fertil-izer), and one from Satureja cuneifolia Ten. (organic fertilizer) by a spectrophotometric method of Ellman using ELISA microplate-reader at 1 mg/ml concentration. In addition, a number of single components widely encountered in most of the essential oils [y-terpinene, 4-allyl anisole, (-)-carvone, dihydrocarvone, (-)-phencone, cuminyl alcohol, cumol, 4-isopro-pyl benzaldehyde, trans-anethole, camphene, iso-borneol, (-)-borneol, L-bornyl acetate, 2-decanol, 2-heptanol, methyl-heptanol, farnesol, nerol, iso-pulegol, 1,8-cineole, citral, citronel-lal, citronellol, geraniol, linalool, ?-pinene, ?-pinene, piperitone, iso-menthone, menthofu-rane, linalyl oxide, linalyl ester, geranyl ester, carvacrol, thymol, menthol, vanilline, and eu-genol] was also screened for the same activity in the same manner. Almost all of the essential oils showed a very high inhibitory activity (over 80%) against both enzymes, whereas the single components were not as active as the essential oils. © 2008, Verlag der Zeitschrift für Naturforschung. All rights reserved.Öğe Comparison of essential oil compositions of some natural and cultivated endemic sideritis species(2011) Gümüşçü A.; Tugay O.; Kan Y.In this study, some yield components and essential compositions of some endemic Sideritis species were investigated. These species are very important for its economical value and utilization for human health. This study carried out at the experimental fields of Cumra High Educational High College and laboratories of Department of Field crops, Faculty of Agriculture, in 2008 and 2009 years. Some characteristics of natural and cultivated plants were determined and essential oil compositions were given comparatively. The collected and cultivating species were Sideritis congesta P.H. Davis and Sideritis condensata Boiss. & Heldr. Essential oil ratio of the cultivated plants were for S. congesta and S. condensata, 0.11%, 0.016%, respectively and natural plants were 0.027%, 0.020%, respectively. According to analyses, the most important components were (3-pinene (28.43%), a-pinene (20.14%), cubebol (16.98%) for cultivated S. congesta; caryophyllene (23.96%), germacrene (23.91%) for cultivated S. condensata. The other components of natural plants were (3-pinene (19.83%), a-pinene (14.61%) for natural S. congesta; caryophyllene (0.67%), germacrene (0.62%) for natural S. condensata.Öğe Composition of essential oil of Cuminum cyminum L. according to harvesting times(2007) Kan Y.; Kartal M.; Özek T.; Aslan S.; Başer K.H.C.The cumin (Cuminum cyminum L.) is an annual plant of Apiaceae. It is generally used as a food additive for increasing the flavour of different food preparations. The fruits (often called seed )are rich in essential oil with the main constituents at different harvesting time being cumin aldehyde (19.9-23.6%), p-mentha-1,3-dien-7-al (11.4-17.5 %) and p-mentha-1,4-dien-7-al (13.9-16.9). The results of GC and GC/MS analysis showed that the fruits should be harvested at the ripe stage for ideal volatile oil yield and composition. The effect of different harvesting times on the yield and ratio of main components of the essential oil are evaluated.Öğe Composition of essential oil of fennel fruits cultivated at different conditions [Farkli koşullarda yeti?sti?ri?len rezene meyveleri?ni?n uçucu ya? bi?lesenleri?](2006) Kan Y.; Kartal M.; Aslan S.; Yildirim N.The fennel (Foenicilum vulgare Miller subsp. vulgare var. dulce (Miller) is an annual plant of Apiaceae. It is widely used as flavouring agent in foodstuffs. It also is used commonly a as stimulation of gastrointestinal in folk medicine. The fruits are rich in essential oil and the main constituents at different cultivated conditions were found to be trans-anethole 60.6-87.0 %, anisaldehyde 6.1-21.3 %, estragole 3.2-11.7%, ?-fenchone 0.7-3.2 %, limonene 0.3-2.5 %, carvone 0.3-1.0 % and cis-anetol 0.2-0.9 %. The results of GC and GC/MS analysis showed that the fruits should be cultivated at nitrogenous conditions for volatile oil yield and composition. The effect of different fertilizers and doses on the yield and ratio of main components of the volatile oil are evaluated.Öğe Determination of antiviral activity and cytotoxicity of selected sage (Salvia L.) species(2011) Özçelik B.; Erdo?an Orhan I.; Kan Y.The objective of this study was to examine antiviral property and cytotoxicity of the extracts prepared from the selected Salvia species (Lamiaceae) growing in Turkey. The chloroform and methanol extracts from 14 Salvia species (S. albimaculata, S. aucheri var. canescens, S. candidissima subsp. occidentalis, S. ceratophylla, S. cryptantha, S. cyanescens, S. frigida, S. forskahlei, S. halophila, S. migrostegia, S. multicaulis, S. sclarea, S. syriaca, and S. verticillata subsp. amasiaca) were tested against Herpes simplex (type-1, HSV-1) and Parainfluenza (type-3, PI-3) using Madin-Darby Bovine Kidney and Vero cell lines. Cytotoxicity of the extracts was determined as maximum non-toxic concentrations (MNTCs). The chloroform extracts of S. cyanescens and S. microstegia were found to inhibit both HSV-1 and PI-3 effectively. Therefore, these species could proceed to further evaluation for their possible antiviral components.Öğe Medicinal plants with antiaging effect cultivated in our country [Ülkemizde kültürü yapılan antiaging etkili tıbbi bitkiler](Turkiye Klinikleri, 2008) Kan Y.Since ancient times the herbal drugs have been used in Turkey for different purposes, such as food, drug, perfumery, and cosmetics. For herbal products, it is necessary to establish good agriculture practice to ensure appropriate and consistent quality of medicinal plant. Because medicinal plants have physiologically strong effects as on human organism, all the steps from plant to drug must be controlled until they reach at consumer. Cultivation conditions such as climate, soil, fertilizer, and irrigation influence the effective compounds such as essential oil, flavonoid, alkaloid, glycoside, and vitamin. In this study, in our country, properties of the medicinal plants cultivated in our country and used for antiaging effects have been investigated. © 2008 by Türkiye Klinikleri.
