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    O-alkylation of pyridine aldo- and ketoximes with dihalohydrins under phase-transfer conditions
    (TAYLOR & FRANCIS INC, 2007) Kocak, Abmet; Kurbanli, Sultan; Malkondu, Sait
    Phase-transfer-catalyzed alkylation of (E)-pyridine aldo- and (E)-ketoximes with dihalohydrins in the benzene (or DMSO)/10% aq. NaOH system in the presence of tetradecylammonium bromide proceeds regiospecifically to afford the corresponding O-halohydrins in good yields. In this study, first O-halohydrin derivatives were converted into glycidyl ether derivatives, and then a new series of amino alcohols were synthesized by the condensation of amines with these glycidyl ethers.