O-alkylation of pyridine aldo- and ketoximes with dihalohydrins under phase-transfer conditions
Küçük Resim Yok
Tarih
2007
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TAYLOR & FRANCIS INC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Phase-transfer-catalyzed alkylation of (E)-pyridine aldo- and (E)-ketoximes with dihalohydrins in the benzene (or DMSO)/10% aq. NaOH system in the presence of tetradecylammonium bromide proceeds regiospecifically to afford the corresponding O-halohydrins in good yields. In this study, first O-halohydrin derivatives were converted into glycidyl ether derivatives, and then a new series of amino alcohols were synthesized by the condensation of amines with these glycidyl ethers.
Açıklama
Anahtar Kelimeler
amino alcohols, condensation, dihalohydrins, epoxides, pyridine aldo- and ketoximes
Kaynak
SYNTHETIC COMMUNICATIONS
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
37
Sayı
07.09.2020
