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Öğe Pyometranın nadir nedeni: Apendiksin Karsinoid Tümörü(2016) Yılmaz, Setenay Arzu; Acar, Fahrettin; Kerimoğlu, Özlem Seçilmiş; Pekin, Aybike Tazegül; İncesu, Feyza; Çelik, ÇetinPiyometra uterin kavite içerisinde enfekte pürülan materyalin birikmesidir ve uterusun doğal drenajının bozulduğu durumlarda görülmektedir. En yaygın nedeni jinekolojik kanserlerdir. Apendiksin karsinoid tümörlerinde teşhis genellikle genç hastalarda akut apandisit tanısı ile yapılan apendektomilerde konulur. Biz bu olguda tuba uterinaya fistülize apendiksin karsinoid tümörü sonucu gelişen piyometra olgusunu sunmayı amaçladıkÖğe The relationship between Polycystic ovary syndrome and vitamin D levels(GALENOS YAYINCILIK, 2015) Yılmaz, Setenay Arzu; Altınkaya, Sündüz Özlem; Kebabcılar, Ayşe Gül; Kerimoğlu, Özlem Seçilmiş; Pekin, Aybike Tazegül; Abuşoğlu, Sedat; Çelik, ÇetinObjective: The main aim of this study was to determine the association of serum 25-hydroxyvitamin D (25-OH D) levels with hormonal, clinical and metabolic profile in patients with and without Polycystic ovary syndrome (PCOS). Materials and Methods: Forty-eight normal-weight (body mass index (BMI) of 19-24.99 kg/m(2)) women with PCOS, 36 overweight (BMI of 25-29.9 kg/m(2)) women with PCOS and 56 normal-weight controls participated in the study. Blood samples were collected in the early follicular phase (between day 2 and day 5 of the menstrual cycle) at 9: 00 am after an overnight fast. Circulating concentrations of 25-OH D, luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, TSH, free testosterone, dehydroepiandrosterone sulphate (DHEA-SO4), 17-hydroxyprogesterone, sex hormone-binding globulin (SHBG), fasting insulin, fasting glucose, and lipid profile were assessed. Results: Normal weight (BMI 19-24.99 kg/m(2)) and overweight (BMI 25-29.99 kg/m(2)) women with PCOS were compared with normal-weight controls and lower 25-OH D levels were found in both PCOS groups (p<0.05 and p<0.01, respectively 25-OH D significantly negatively correlated with waist circumference (WC), waist-to-hip ratio (WHR), free testosterone and modified Ferriman-Gallwey scores, however, there was a positive correlation between 25-OH D and SHBG levels (p<0.05). Conclusion: Our findings suggest that PCOS is associated with hypovitaminosisÖğe Serum Levels of Neopterin In Gestational Diabetes Mellitus: The Relationship With Apgar Scores(SPRINGER HEIDELBERG, 2015) İpekci, Süleyman Hilmi; Kebapcılar, Ayşe Gül; Yılmaz, Setenay Arzu; İlhan, Tolgay Tuyan; Pekin, Aybike Tazegül; Abuşoğlu, Sedat; Ünlü, Ali; Çelik, Çetin; Annagur, AliPurpose This study was designed to evaluate neopterin levels and low Apgar scores in pregnancies with gestational diabetes mellitus (GDM) vs. normal control pregnancies. Methods We carried out a cross-sectional study by enrolling 81 pregnant women with GDM and 38 pregnant women without GDM. Results Maternal and cord blood neopterin levels were higher in women with GDM. There was a significant positive association between fasting blood glucose levels and maternal serum neopterin levels. The results of 50-g oral glucose challenge tests revealed a correlation between maternal and cord neopterin levels. Pregnancies complicated by GDM exhibited lower fetal Apgar scores than those of control subjects. The levels of cord blood neopterin were inversely correlated with an fetal Apgar score of 1 min in patients with GDM. Conclusions Patients with GDM had higher maternal and cord blood neopterin levels, and the cord blood neopterin levels are inversely associated with lower Apgar scores in women with GDM. The neopterin levels might be potential predictors of low fetal Apgar scores in women with GDM.