Serum Levels of Neopterin In Gestational Diabetes Mellitus: The Relationship With Apgar Scores
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER HEIDELBERG
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose This study was designed to evaluate neopterin levels and low Apgar scores in pregnancies with gestational diabetes mellitus (GDM) vs. normal control pregnancies. Methods We carried out a cross-sectional study by enrolling 81 pregnant women with GDM and 38 pregnant women without GDM. Results Maternal and cord blood neopterin levels were higher in women with GDM. There was a significant positive association between fasting blood glucose levels and maternal serum neopterin levels. The results of 50-g oral glucose challenge tests revealed a correlation between maternal and cord neopterin levels. Pregnancies complicated by GDM exhibited lower fetal Apgar scores than those of control subjects. The levels of cord blood neopterin were inversely correlated with an fetal Apgar score of 1 min in patients with GDM. Conclusions Patients with GDM had higher maternal and cord blood neopterin levels, and the cord blood neopterin levels are inversely associated with lower Apgar scores in women with GDM. The neopterin levels might be potential predictors of low fetal Apgar scores in women with GDM.
Açıklama
Anahtar Kelimeler
Neopterin, Inflammation, Gestational Diabetes Mellitus, Apgar Score
Kaynak
Archieves of Gynecology And Obstetrics
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
292
Sayı
1
Künye
İpekci, S. H., Kebapcılar, A. G., Yılmaz, S. A., İlhan, T. T., Pekin, A. T., Abuşoğlu, S., Ünlü, A., Çelik, Ç., Annagur, A., (2015). Serum Levels of Neopterin In Gestational Diabetes Mellitus: The Relationship With Apgar Scores. Archieves of Gynecology And Obstetrics, 292(1), 103-109.
DOI 10.1007/s00404-015-3615-3
