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Öğe Does "cerebellar liponeurocytoma" always reflect an expected site? An unusual case with a review of the literature(TERMEDIA PUBLISHING HOUSE LTD, 2014) Karabagli, Pinar; Sav, Aydin; Pamir, NecmettinA rare tumour, cerebellar liponeurocytoma, is classified into glioneuronal tumours under the 2000 World Health Organization (WHO) classification of tumours of the central nervous system. The current 2007 WHO classification, therefore, assigns grade II to the cerebellar liponeurocytoma. Tumours are predominantly localized in cerebellar hemispheres, and the second most common location is the vermis. To date, approximately 40 reported cases of cerebellar and 10 cases of supratentorial introventricular liponeurocytoma have been reported. In this report, an unusual case of cerebellar liponeurocytoma was presented with extracerebellar location. In the future tumour classification, it should be considered that liponeurocytomas are not restricted only to the cerebellum, but they are located in supratentorial areas as well.Öğe Does "Cerebellar Liponeurocytoma" Always Reflect an Indolent Biological Behaviour?: An Unusual Case With Review of The Literature(JOURNAL NEUROLOGICAL SCIENCES, 2012) Sav, Aydin; Karabagli, Pinar; Deda, HalukA rare tumor, cerebellar liponeurocytoma is classified into glioneuronal tumors under the 2000 World Health Organization (WHO) classification of tumors of the central nervous system. The current 2007 WHO classification assigns grade II to the cerebellar liponeurocytoma. Tumors are predominantly localized in cerebellar hemispheres, and the second most common location is the vermis. In the report, an unusual case of cerebellar liponeurocytoma was presented with clinically and histologically aggresive features. In future tumor classification, it should be considered that its biologic behavior is not as indolent as suggested by current literature. This tumor should be regarded as an uncertain malignant potential lesion when mitoses are present and the MIB-1 positive cells are more than 10%.Öğe Does Cerebellar Liponeurocytoma Always Reflect an Indolent Biological Behaviour?: An Unusual Case With Review of The Literature(2012) Sav, Aydin; Karabaglı, Pinar; Deda, HalukNadir bir tümör olarak serebellar liponörositoma, santral sinir sistemi tümörlerinin 2000 Dünya Sağlık Örgütü (DSÖ) sınıflamasında glionöronal tümörler başlığı altında sınıflandırılmıştır. Son 2007 DSÖ sınıflamasında ise serebellar liponörositoma, derece II olarak tanımlanmıştır. Bu tumor başlıca serebellar hemisferlerde, 2. sıklıkta ise vermiste yerleşim gösterirler. Makalede klinik ve histolojik olarak agresif özellikler göstermesi nedeniyle farklılık gösteren bir serebellar liponörositoma olgusunu sunduk. Gelecek tümör sınıflamasında bu tümörlerin biyolojik davranışının literatürde iddia edildiği kadar masum olmadığı gözönüne alınmalıdır. Bu tumor MIB-1 pozitif hücreler %10'dan fazla olduğunda ve mitozların varlığında malignite potansiyeli kesin olmayan bir lezyon olarak algılanmalıdır.Öğe Giant Cell Ependymoma of The Lumbar Spine: Case Report and Review of The Literature(JOURNAL NEUROLOGICAL SCIENCES, 2011) Karabagli, Pinar; Deda, Haluk; Sav, AydinGiant cell ependymoma (GCE), is a extremely rare subtype of ependymoma. To date 14 cases have been documented in the literature. Here we present a case of GCE occuring in a 32-year-old patient with a 3-month history of progressively increasing pain in low back and right leg. Magnetic Resonance Imaging demonstrated a well circumscribed and enhancing intramedullar mass extending from L1 to L3. Tumor was totally resected. Histological and immunohistochemical findings were consistent with low grade giant cell ependymoma. This case is the first GCE of a lumbar spinal cord. All literature related to GCE was reviewed, and the clinic, radiologic, prognostic and histopathologic characteristics associated with such lesions are discussed, based on the presented case.
