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    Effects of Coenzyme Q10 Supplementation on Doxorubicin Treatment-induced Cognitive Dysfunction in Rats
    (WILEY-BLACKWELL, 2016) Okudan, Nilsel; Belviranli, Muaz; Sezer, Tugba
    [Abstract not Available]
  • Küçük Resim
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    Quantitative assessment of the effect of acute anaerobic exercise on macular perfusion via swept-source optical coherence tomography angiography in young football players
    (SPRINGER, 2019) Karakucuk, Yalcin; Okudan, Nilsel; Bozkurt, Banu; Belviranli, Muaz; Sezer, Tugba; Gorcuyeva, Sona
    Aim To evaluate the effect of acute anaerobic exercise on macular perfusion measured by swept-source optical coherence tomography angiography (SS-OCTA) in young football players. Materials and methods Football players with ages between 18 and 20 years were included into the study. After a detailed ophthalmological examination, physiological parameters including height (cm), body weight (kg), body fat percentage (%), systemic blood pressure (BP) (mmHg), hematocrit values (%), oxygen saturation pO(2) (%) and heart rate (bpm) were recorded. Intraocular pressure (IOP) (mmHg) and SS-OCTA using DRI OCT Triton (Topcon, Tokyo, Japan) were measured immediately before and after Wingate test. Results Out of 20, 16 participants completed the study. All participants were males with a mean age of 18.12 +/- .34 years. Systolic BP, hematocrit and heart rate increased, while pO(2) and IOP decreased remarkably after Wingate test (p < .01). After anaerobic exercise, there was an increase in mean FAZ area in superficial capillary plexus (FAZs) which was not significant (p = .13), while decrease in FAZ area in deep capillary plexus (FAZd) (mm(2)) was remarkable (p = .04). No changes were observed in mean vessel density (VD) (%) in superficial capillary plexus (VDs), deep capillary plexus (VDd), choriocapillaris (VDcc), central macular thickness (CMT) (mu m) and subfoveal choroidal thickness (SFCT) (mu m) after Wingate test (p > .05). FAZd and some of the VD parameters showed a significant correlation with BP (p < .05). Conclusion Acute anaerobic exercise seems not to alter either mean VD in retina and choroid or CMT and SFCT. Among OCTA parameters, only FAZd decreased remarkably.