Yazar "Yilmaz, Mevlut" seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim Yok
    Öğe
    Comparison of the Effect of Unilateral Intravitreal Bevacizumab and Ranibizumab Injection on Diabetic Macular Edema of the Fellow Eye
    (MARY ANN LIEBERT, INC, 2013) Bakbak, Berker; Ozturk, Banu Turgut; Gonul, Saban; Yilmaz, Mevlut; Gedik, Sansal
    Purpose: To find out whether intravitreally administered bevacizumab and ranibizumab affect the contralateral, untreated, eyes of patients with bilateral diabetic macular edema (DME). Methods: A retrospective review of patients with bilateral DME, who were treated with intravitreal bevacizumab or ranibizumab, was performed. All enrolled patients received intravitreal 1.25mg bevacizumab or 0.5mg ranibizumab in the eye with more severe macular edema. As outcome measures, best-corrected visual acuity (BCVA) was assessed with the Early Treatment Diabetic Retinopathy Study chart and central foveal thickness (CFT) measurement was obtained using optical coherence tomography-3 before and at 2 and 4 weeks after injections. Results: The study included 55 eyes of 55 patients who received bevacizumab (group 1) and 32 eyes of 32 patients who received ranibizumab (group 2). The mean age of the 55 patients [35 female (63.6%), 20 male (36.4%)] in group 1 was 54.3112.67 years, and the mean age of the 32 patients [20 female (62.5%), 12 male (37.5%)] in group 2 was 56.01 +/- 13.29 years. The median BCVA in the uninjected eye showed no statistically significant change at any visit after either bevacizumab or ranibizumab injection (P=0.302, P=0.582, respectively). In group 1, the median CFT in the uninjected eye was 417m at baseline; this was reduced to 401m at 2 weeks and 372m at 4 weeks. The change in CFT was found to be statistically significant (P=0.009). No statistically significant change was found in the median CFT of uninjected eyes of patients treated with ranibizumab (399, 403, and 407m before and at 2 and 4 weeks after treatment, respectively). Conclusions: Compared with ranibizumab, intravitreal administration of bevacizumab resulted in a greater decrease in macular thickness in the untreated eye, in patients with bilateral DME.
  • Küçük Resim Yok
    Öğe
    Correlation of Corneal Endothelial Cell Density with Corneal Tomographic Parameters in Eyes with Keratoconus
    (TURKISH OPHTHALMOLOGICAL SOC, 2017) Bozkurt, Banu; Yilmaz, Mevlut; Mesen, Ali; Kamis, Umit; Koktekir, Bengu Ekinci; Okudan, Suleyman
    Objectives: To examine changes in corneal endothelial cell density (ECD) in different stages of keratoconus and evaluate its correlation with corneal tomographic parameters. Materials and Methods: Two hundred six patients with keratoconus were enrolled in the study. Corneal topography was performed by Sirius (CSO, Italy), which has a rotating Scheimpflug camera and a Placido disc topographer. Automatic endothelial analysis was done with the non-contact endothelial microscope (20x probe) of Confoscan-4 (NIDEK, Japan). The eyes were classified into stages based on steepest keratometric value as follows: mild <45 D; moderate 45-52 D; severe >52 D and according to thinnest cornea thickness (TCT) as <400 mu m, 400-450 mu m, and >450 mu m. Tomographic and endothelial cell parameters were compared among the groups using Kruskal-Wallis test and the correlations between them were analyzed using Spearman correlation. Results: The study included 391 eyes of 100 male (24.29 +/- 7.7 years, range 11-47 years) and 106 female (26.26 +/- 7.5 years, range 13-45 years) patients (p=0.07). Mean ECD values were 2628 +/- 262 cells/mm(2), 2541.9 +/- 260.4 cells/mm(2), and 2414.6 +/- 384.3 cells/mm(2) in mild, moderate, and severe keratoconus, respectively (p<0.001) and 2592.3 +/- 277 cells/mm(2), 2502 +/- 307 cells/mm(2) and 2348 +/- 296 cells/mm(2) in corneas with TCT values >450 mu m, 400-450 mu m, and <400 mu m, respectively (p<0.001). ECD showed significant negative correlation with keratometric and elevation parameters and positive correlation with pachymetric parameters (p<0.05). Conclusion: As endothelial cell numbers seem to decrease with the progression of keratoconus, specular/confocal microscopy screening should be carried out, especially in eyes with advanced stages and corneas with TCT <400 mu m.
  • Küçük Resim Yok
    Öğe
    Posterior Corneal Steepening in Posterior Polymorphous Corneal Dystrophy
    (LIPPINCOTT WILLIAMS & WILKINS, 2015) Bozkurt, Banu; Ozkan, Fehmi; Yilmaz, Mevlut; Okudan, Suleyman
    Purpose The aim was to evaluate the anterior and posterior corneal topographic characteristics of three patients with posterior polymorphous corneal dystrophy (PPCD) using a rotating Scheimpflug camera combined with a Placido disc system (Sirius, CSO, Italy). Case Reports Two children with unilateral PPCD and a 53-year-old woman with bilateral PPCD were diagnosed by the presence of vesicles and railroad track lesions at the level of the Descemet membrane with slitlamp biomicroscopy and in vivo confocal microscopy. Anisometropic and/or meridional amblyopia was detected in both children. In the 16-year-old child, there was unilateral anterior corneal steepening with high astigmatism (plano -7.00 x170) in the eye with PPCD. The 5-year-old boy had unilateral axial myopia and against-the-rule corneal astigmatism (-12.00 -2.00 x90). Corneal topography of the woman revealed with-the-rule astigmatism and thin corneas (464 m OD and 445 m OS) in both eyes. Posterior corneal steepening greater than 25 m either in a vertical or in a horizontal pattern changing with the orientation of the railroad track band lesions was detected in all subjects. Conclusions Besides anterior corneal changes, PPCD seems to cause posterior corneal elevation, which necessitates corneal tomographic evaluation. In unilateral or highly asymmetric cases, children with PPCD should be screened for amblyopia.
  • Küçük Resim Yok
    Öğe
    Quantitative Assessment of Anterior Chamber Inflammation in Patients with Retained Presumed Intraocular Cotton Fiber after Phacoemulsification
    (TAYLOR & FRANCIS INC, 2013) Bakbak, Berker; Gedik, Sansal; Ozturk, Banu Turgut; Koktekir, Bengu Ekinci; Gonul, Saban; Yilmaz, Mevlut
    Purpose: To evaluate anterior chamber inflammation in eyes with retained presumed intraocular cotton fibers after small-incision cataract surgery. Methods: Fourteen patients with retained presumed intraocular cotton fibers after phacoemulsification were evaluated for anterior chamber inflammation. The control group consisted of 15 patients with no postoperative intraocular cotton fibers. An aqueous flare meter was used to evaluate anterior chamber reaction 1 day, 1 week, and 1 month postoperatively. Results: Retained cotton fibers were detected in the anterior chamber in 6 cases, and in the corneal incision site, extending into the anterior chamber, in 8 cases. The mean flare values at each postoperative visit were statistically similar between two groups. Conclusions: Following cataract surgery, retained presumed intraocular cotton fibers did not cause any additional inflammation in the eye within the short term. In contrast to other intraocular foreign bodies, which may cause severe inflammation, retained intraocular cotton fibers seem to be well tolerated following cataract surgery.