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Öğe Comparison of semen profile and frequency of chromosome aneuploidies in sperm nuclei of patients with varicocele before and after varicocelectomy(WILEY, 2009) Acar, H.; Kilinc, M.; Guven, S.; Yurdakul, T.; Celik, R.Semen profile and meiotic segregation products are important for assessing aneuploidy risk and risk of resulting infertility. To determine the effect of varicocelectomy on semen profile and aneuploidy frequency, we investigated semen profile and aneuploidy frequency of selected chromosomes in patients with varicocele before and after varicocelectomy. Chromosomal aneuploidy for selected chromosomes was evaluated using chromosome-specific DNA fluorescence in situ hybridisation (FISH) probes. There was a significant difference in the level of normal sperm morphology before and after varicocelectomy (P > 0.007). There were no significant differences in aneuploidy frequency of chromosomes 1, 16, 17 and 18 in sperm nuclei obtained from patients before varicocelectomy compared with 6-7 months after varicocelectomy (P > 0.05), although FISH analysis with chromosomes 17 and 18 combination showed a higher aneuploidy frequency before varicocelectomy than after varicocelectomy (7.81 +/- 9.67 versus 4.03 +/- 1.46 respectively). In conclusion, varicocele seems to affect the semen profile but minimally affects aneuploidy frequency. Varicocelectomy demonstrates a repairing effect on the semen profile and contributes to a slight decrease in aneuploidy frequency in some but not all chromosomes.Öğe Epididimoorchitis as a Complication of Brucellosis(KARGER, 1995) Yurdakul, T.; Sert, U.; Acar, A.; Karalezli, G.; Akçetin, Z.A study of 84 patients who were diagnosed with epididymo-orchitis between July 1987 and September 1993 is presented, Brucellosis was a complication in 14 cases (17%), All 14 cases had elevated agglutination titers. Brucella blood culture was found to be positive in 4 of 14 cases (28.5%). Standard therapy regime (streptomycin plus tetracycline) was effective in 13 of 14 (93%) cases.Öğe Lack of significant association between chromosome Y microdeletion and varicocele in Turkish patients(MEDECINE ET HYGIENE, 2006) Acar, Hasan; Kılınç, Mehmet; Yurdakul, T.; Güven, Selçuk[Abstract not Available]Öğe Massive Retroperitoneal Hemorrhage Due to Bilateral Renal Angiomyolipoma in a Patient With Tuberous Sclerosis(2009) Kılıç, Ö.; Yurdakul, T.; Kaynar, M.; Özbek, O.; Baba, F.Renal angiomyolipoma (AML) is one of the most common urological manifestations of tuberous sclerosis complex (TS). These lesions may cause significant morbidity, mostly related to complications from bleeding. Here, we present a patient with bilateral multiple renal AML associated with TS who underwent bilateral renal surgery. The case is discussed in the light of clinical findings and treatment modalities.