Neonatal septicemia in tertiary hospitals in Konya, Turkey

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dc.contributor.authorTarakci, Nuriye
dc.contributor.authorKonak, Murat
dc.date.accessioned2020-03-26T19:54:46Z
dc.date.available2020-03-26T19:54:46Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: Neonatal sepsis is one of the leading causes of mortality and morbidity in the developing world. The present study aims to determine the incidence and risk factors of neonatal sepsis in a single center over a four-year period. Material and Method: This is a retrospective study of all cases of culture-proven neonatal sepsis admitted in the neonatal intensive care unit of a single center between January 2013 and December 2016. Clinical features, risk factors, microbiological and biochemical results, and mortality rates were recorded. Associations between risk factors and mortality were investigated. Results: The prevalence rate of neonatal sepsis was 2.7 per 1000 live births (94/30545) and 9.3 per 1000 neonatal admissions (94/10133). Low birth weight (<= 2500g) was recorded in 79 (84%) neonates with sepsis. There was at least one risk factor in all cases. Gram-negative bacteria were more frequently isolated than gram-positive bacteria (63.8% (60/94) vs. 29.7% (28/94)). Klebsiella pneumonia was predominant in both early-onset sepsis and late-onset sepsis (53% (16/30), 29.7% (19/64) respectively). Late-onset sepsis episodes attributed to Klebsiella pneumonia were associated with the highest sepsis-related mortality (41.7%). Discussion: Klebsiella pneumonia was found to be the most common agent in neonatal sepsis and responsible for sepsis-related mortality in this study. Prevalence of neonatal sepsis, its pathogens and risk factors differ in different parts of the world. Region-specific strategies to prevent new infections should be encouraged.en_US
dc.identifier.doi10.4328/JCAM.5774en_US
dc.identifier.endpage191en_US
dc.identifier.issn1309-0720en_US
dc.identifier.issn1309-2014en_US
dc.identifier.issue3en_US
dc.identifier.pmid#YOKen_US
dc.identifier.startpage187en_US
dc.identifier.urihttps://dx.doi.org/10.4328/JCAM.5774
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36794
dc.identifier.volume9en_US
dc.identifier.wosWOS:000429961400002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDERMAN MEDICAL PUBLen_US
dc.relation.ispartofJOURNAL OF CLINICAL AND ANALYTICAL MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectNeonatal Sepsisen_US
dc.subjectNeonatal Intensive Care Uniten_US
dc.titleNeonatal septicemia in tertiary hospitals in Konya, Turkeyen_US
dc.typeArticleen_US

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