Cutaneous basophil hypersensitivity reaction in immunomodulated broiler chicks
Küçük Resim Yok
Tarih
1999
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A skin test to assess cutaneous basophil hypersensitivity (CBH) was evaluated in the interdigital skin of chickens grouped according to age. A total of 45 broiler Shaver hybrid chicks were used. Cutaneous basophil hypersensitivity was determined in the interdigital skin of 10- and 30- day-old chicks by a single intradermal injection of phytohemagglutinin-P (200 mu g). In order to induce immunosuppersion, dexamethason dosed 3mg/kg body weight was injected IM for 3 days; to stimulate the immune system of the animals, levamisole was applied at 3 mg/kg body weight in the drinking water for 3 days. The effect of immunomodulation on the progress of the skin reaction for CBH was evaluated 12, 24 and 24 hours after injection. The skin reaction, as indicated by a significant (P<0.05) increase in the mean interdigital skin thickness, was detectable the day after injection in both groups. In conclusion, the test can be recommended to assess in vivo cell-mediated immunity even in 10-day-old broiler chicks.
Açıklama
Anahtar Kelimeler
cutenous basophil hypersensitivity, immunosuppression, immunostimulation, broiler
Kaynak
TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
23
Sayı
6
