Lateral Lomber Kanal Stenozuna Bağlı Ağrının Tedavisinde Karbamazepin'in Etkinliği
Küçük Resim Yok
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Bu çalışmada, birçok nöropati ve nevralji'de analjezik amaçlı kullanılan karbamazepin'in, lateral lomber kanal stenozlu hastalarda ağrı üzerine etkinliğinin olup, olmadığı araştırıldı. Çalışmaya yaşları 32 ile 74 arası ve 7'si kadın toplam 14 lateral kanal stenozlu hasta alındı. Bu hastaların en az 6 ay süreli bel ve/veya bacak ağrısı ana yakınması vardı ve steroid olmayan antienflamatuar ve basit analjezik ilaçlarla ağrıları geçmiyordu. Bu hastalara toplam 6 hafta süreyle karbamazepin verildi. 400 mg/ gün dozunda başlanan tedaviye iki hafta sonra cevap alınamayanlarda 800 mg/gün ile devam edildi. Hastaların tedavi öncesi ve sonrası ağrı semptomları, bacak ağrısı şiddeti ve fonksiyonel bozukluk skoru ile değerlendirildi. Hastaların ağrıları tedavi sonrası anlamlı derecede azaldı (p0.01,X2:10) Sonuç olarak lateral kanal stenozunda ağrıyı gidermek amacıyla karbamazepin'i yeni bir alternatif olarak önermekteyiz.
In this study, we investigated whether carbamazepine which usually is used in many diseases characterized by neuropathy or neuralgia to reduce pain, has an an¬algesic effect in patients with lateral canal stenosis. 14 patients (7 women, 7 men) with lateral canal steno¬sis whose age ranged between 32 and 74 were included in the study. These patients had low back pain and/or sciatica at least for six months and they didn't respond to other medical drugs including nonsteroidal antiin-flammatory drugs and analgesics. They were adminis¬tered 400 mg/bid oral carbamazepine as initial dose for two weeks. When they didn't respond to that dose, it was increased to 800 mg/bid for four weeks. The patients pain were evaluated by the leg pain severity and overall func¬tional disability score before and after treatment. After treatment, the pain was significiantly reduced in these patients (p<0.01, K-.IO). In conclusion, we propose carbamazepine in the treat¬ment of lateral canal stenosis as a new alternative drug.
In this study, we investigated whether carbamazepine which usually is used in many diseases characterized by neuropathy or neuralgia to reduce pain, has an an¬algesic effect in patients with lateral canal stenosis. 14 patients (7 women, 7 men) with lateral canal steno¬sis whose age ranged between 32 and 74 were included in the study. These patients had low back pain and/or sciatica at least for six months and they didn't respond to other medical drugs including nonsteroidal antiin-flammatory drugs and analgesics. They were adminis¬tered 400 mg/bid oral carbamazepine as initial dose for two weeks. When they didn't respond to that dose, it was increased to 800 mg/bid for four weeks. The patients pain were evaluated by the leg pain severity and overall func¬tional disability score before and after treatment. After treatment, the pain was significiantly reduced in these patients (p<0.01, K-.IO). In conclusion, we propose carbamazepine in the treat¬ment of lateral canal stenosis as a new alternative drug.
Açıklama
Anahtar Kelimeler
Rehabilitasyon, Romatoloji
Kaynak
Romatoloji ve Tıbbi Rehabilitasyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
3
Künye
Üstün, M. E., Özerbil, Önder M., Güney, Ö., Kocaoğullar, Y., (1997). Lateral Lomber Kanal Stenozuna Bağlı Ağrının Tedavisinde Karbamazepin'in Etkinliği. 8(3), 269-272.
